Heart transplantation in Finland 1985-1995

BACKGROUND: Clearance of large molecules from the interstitial space is an important function of lymphatics and is affected by local pathologic changes. OBJECTIVE: To determine if the clearance rate of interstitially injected albumin is correlated to tumour characteristics and outcome in women with invasive breast cancer. METHOD: In a consecutive series of women coming to biopsy for suspected breast cancer, technetium-tagged albumin was injected into the tissue adjacent to the palpable mass. The isotope disappearance rate was measured over two hours. Also assessed were the maximum vessel density (MVD-using Factor VIII polyclonal antisera), the proliferation rate (using Ki-67 antisera), node status, tumour size, histologic and nuclear grade, mitotic rate, and p53 and c-erbB-2 oncoproteins. All patients were followed until relapse and for a minimum of 10 years. RESULTS: In multivariate analysis, an association between relapse-free survival and isotope clearance rate was suggested (p = 0.024). The best outcome was seen in patients with the least isotope clearance. Node status, size, histologic and nuclear grade, and mitotic rate correlated with survival. MVD did not correlate with survival and was inversely related to the isotope clearance rate. Tumour proliferation rate, and the c-erbB-2 and p53 oncoproteins did not relate to outcome. CONCLUSION: The role of lymphatics in breast cancer is difficult to study. Measurement of interstitial clearance may be a useful technique and could be a prognostic factor.     

Heat and Mass Transfer Analogy Studies of Binary Liquid Mixture in Comparison with Eteanol-n-Heptane Evaporating to Air

An expenmental and theoretical study of heat and mass transfer analogy and a comparison of that to a binary liquid mixture evaporation is presented. Common organic solvents, ethanol and n-heptane, were used to form an alcohol - hydrocarbon mixture. Studies were carried out in a horizontal rectangular channel having air flow velocities of 0.2 - 0.9 m/s. Heat transfer coefficients were measured with a copper plate resistor and mass transfer coefficients with a square pool. The heat and mass transfer analogy is presented for a system having two evaporating compounds with a fixed value of air flow and verified by measuring and comparing mass transfer coefficients for distilled water with air flow velocities of 0.2 - 0.9 mls. An illustrative example of the use of the theory for industrial ventilation is presented.     

Estimating areal means and variances of forest attributes using the k-Nearest Neighbors technique and satellite imagery

The k-Nearest Neighbor (k-NN) technique has become extremely popular for a variety of forest inventory mapping and estimation applications. Much of this popularity may be attributed to the non-parametric, multivariate features of the technique, its intuitiveness, and its ease of use. When used with satellite imagery and forest inventory plot data, the technique has been shown to produce useful estimates of many forest attributes including forest/non-forest, volume, and basal area. However, variance estimators for quantifying the uncertainty of means or sums of k-NN pixel-level predictions for areas of interest (AOI) consisting of multiple pixels have not been reported. The primary objectives of the study were to derive variance estimators for AOI estimates obtained from k-NN predictions and to compare precision estimates resulting from different approaches to k-NN prediction and different interpretations of those predictions. The approaches were illustrated by estimating proportion forest area, tree volume per unit area, tree basal area per unit area, and tree density per unit area for 10-km AOIs. Estimates obtained using k-NN approaches and traditional inventory approaches were compared and found to be similar. Further, variance estimates based on different interpretations of k-NN predictions were similar. The results facilitate small area estimation and simultaneous and consistent mapping and estimation of multiple forest attributes.     

NMR imaging and differential scanning calorimetry study on drying of pine,birch, and reed pulps and their mixtures

Drying, water fractions, and water distribution were investigated for pine, birch, and reed pulps and pine–birch, pine–reed, and pine–birch–reed pulp mixtures. Gravimetrically determined drying times showed that the drying rates of the pulps decreased at two to four inflection points. Characterizations of the dried pulps by differential scanning calorimetry (DSC) showed a faster removal of free water than freezing and nonfreezing bound waters; all decreased simultaneously, however. DSC also revealed the critical water contents at which the free water and freezing bound water disappeared. The gravimetrically determined inflection points of the drying curves corresponded with the critical points determined by DSC. NMR line widths and images produced by ¹H‐NMR imaging revealed the nature and regions of the pulp drying. The constant growth rate of the NMR line widths with decreasing water content appeared to change at two inflection points, which fell approximately in the same water content regions as the inflection points of the drying curves. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 937–945, 2006     

Usability study of ME2.0

Mobile context-aware applications execute in the background of hosts mobile devices. The applications source process and aggregate hosts’ contextual and personal information. This information is disclosed to ubiquitously pervasive services that adapt their offerings to individual preferences. Unfortunately, many developers continue to ignore the user perspective in context-aware application designs as they complicate their overall task and generate exponential requirements. The additional incorporation of privacy mechanisms in context-aware applications to safeguard context and personal information disclosures also complicates users’ tasks resulting to misconfigured or completely abandoned applications. Misconfigured applications give end-users a false assurance of privacy exposing them to comprising services. We present a usability study on Mobile Electronic Personality Version 2 a privacy enhanced context-aware mobile application for personalising ubiquitous services and adapting pervasive smart-spaces. We draw conclusions on key issues related to user needs, based on user interviews, surveys, prototypes and field evaluations. Users’ needs are evaluated against five themes, learn-ability, efficiency, memorability, errors, satisfaction and privacy contention. In addition, design layout preferences, privacy manageability and consensus design comprehension are also evaluated. Clarity of priorities in context-aware mobile applications shaped by usability studies effectively increases the acceptance of levels of potential users.     

Preparation and characterisation of α-methylstyrene–butadiene latexes for paper coating applications

The purpose of this work is to demonstrate how α-methylstyrene (AMS) can replace styrene in preparing styrene–butadiene (SB) type latexes and to compare the properties of the paper coating of the prepared α-methylstyrene–butadiene emulsion with the commercial styrene–butadiene latex reference sample. A lot of work is nowadays being conducted on different biorefinery concepts replacing fossil oil with biomass based raw materials due to the expected rise of the fossil oil cost. Aromatics can in principle be produced from renewable raw materials, such as lignin, sugars and terpenes for example. The potential methods include thermochemical conversions, catalytic fast pyrolysis, metabolic engineering, catalytic aromatisation and dehydrogenation among others. Terpenes, such as α-limonene and pinene, are possible sources of aromatics, and they can indeed be catalytically converted to p-cymene. Industrial hydrodealkylation and disproportionation processes developed by major petrochemical companies can further convert p-cymene to BTX aromatics or simultaneously dehydrogenate the alkyl chain of p-cymene to styrenic monomers such as α-methylstyrene. Based on the measured paper properties for uncalendered and calendered coated samples, AMS proved to be adequate to replace the oil based styrene in commercial reference SB latexes. Even though the emulsion polymerisation for the α-methylstyrene–butadiene latex was not optimised, almost all tested properties were at least equally good as in the commercial reference sample. α-Methylstyrene containing coating colours had slightly higher viscosity than the other coating colours. Coating colours containing α-methylstyrene seems to have an improved water retention compared to the commercial reference styrene–butadiene latex coating colour and the laboratory prepared styrene–butadiene coating colour. The paper coated with the commercial reference latex containing coating colour was less porous than the other coated papers. Despite of that, both dry and wet surface strength were at least equally good as in the case of the commercial reference latex. The results are promising when thinking of the future development of the bio-based latexes.     

A non‐repudiable negotiation protocol for security service level agreements

Security service level agreements (SSLAs) provide a systematic way for end users at home or in the office to guarantee sufficient security level when doing business or exchanging sensitive personal or organizational data with an online service. In this paper, we propose an SSLA negotiation protocol that implements non‐repudiation with cryptographic identities and digital signatures and includes features that make it resistant to denial of service attacks. The basic version of the protocol does not rely on the use of a trusted third party, and it can be used for all kinds of simple negotiations. For the negotiation about SSLAs, the protocol provides an option to use an external knowledge base that may help the user in the selection of suitable security measures. We have implemented a prototype of the system, which uses JSON Web Signature for the message exchange and made some performance tests with it. The results show that the computational effort required by the cryptographic operations of the negotiation protocol remains at a reasonable level. Copyright © 2014 John Wiley & Sons, Ltd.