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Tomoyuki Fujii Keiichiro Tohgo Masafumi Fujioka Muhamad Safwan Bin Muhamad Azmi Kodai Kikushima Yoshinobu Shimamura 《Fatigue & Fracture of Engineering Materials & Structures》2020,43(9):1917-1927
This paper proposes an alternating bending technique for evaluating fatigue life in the low‐to‐high cycle fatigue regime. A method was developed for estimating the stress, elastic strain, and plastic strain ranges of a plastically deformed specimen subjected to alternating bending with consideration of stress and strain distributions. To evaluate its effectiveness, fatigue testing was conducted using a specimen made of a steel used for pressure vessels. The stress, elastic strain, and plastic strain ranges could be obtained during cyclic bending. The elastic strain amplitude life and plastic strain amplitude life curves were linear in a log–log plot in the low‐to‐high cycle fatigue regime. Hence, the fatigue life under alternating bending could be evaluated using the proposed strain‐based approach. However, these curves could not be predicted using equations with parameters obtained from tensile testing, such as the universal slope method, due to the strain gradient in the specimen. 相似文献
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Samir Abu-Rumeileh Peggy Barschke Patrick Oeckl Simone Baiardi Angela Mammana Andrea Mastrangelo Mhd Rami Al Shweiki Petra Steinacker Anna Ladogana Sabina Capellari Markus Otto Piero Parchi 《International journal of molecular sciences》2022,23(4)
Proenkephalin (PENK) and prodynorphin (PDYN) are endogenous opioid peptides mainly produced in the striatum and, to a lesser extent, in the cerebral cortex. Dysregulated metabolism and altered cerebrospinal fluid (CSF) levels of PENK and PDYN have been described in several neurodegenerative diseases. However, no study to date investigated these peptides in the CSF of sporadic Creutzfeldt–Jakob disease (sCJD). Using liquid chromatography-multiple reaction monitoring mass spectrometry, we evaluated the CSF PDYN- and PENK-derived peptide levels in 25 controls and 63 patients with sCJD belonging to the most prevalent molecular subtypes (MM(V)1, VV2 and MV2K). One of the PENK-derived peptides was significantly decreased in each sCJD subtype compared to the controls without a difference among subtypes. Conversely, PDYN-derived peptides were selectively decreased in the CSF of sCJD MV2K, a subtype with a more widespread overall pathology compared to the sCJD MM(V)1 and the VV2 subtypes, which we confirmed by semiquantitative analysis of cortical and striatal neuronal loss and astrocytosis. In sCJD CSF PENK and PDYN were associated with CSF biomarkers of neurodegeneration but not with clinical variables and showed a poor diagnostic performance. CSF PDYN and PENK-derived peptides had no significant diagnostic and prognostic values in sCJD; however, the distinct marker levels between molecular subtypes might help to better understand the basis of phenotypic heterogeneity determined by divergent neuronal targeting. 相似文献
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Albadr Musatafa Abbas Abbood Tiun Sabrina Ayob Masri AL-Dhief Fahad Taha Omar Khairuddin Maen Mhd Khaled 《Multimedia Tools and Applications》2022,81(17):23963-23989
Multimedia Tools and Applications - Automatic Emotion Speech Recognition (ESR) is considered as an active research field in the Human-Computer Interface (HCI). Typically, the ESR system is... 相似文献
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Elham Sobhanzadeh Nor Kartini Abu Bakar Mhd Radzi Bin Abas Keivan Nemati 《European Journal of Lipid Science and Technology》2011,113(7):862-869
This work reports a simple, rapid, and effective extraction method based on liquid–liquid extraction (LLE) followed by matrix solid‐phase dispersion‐sonication for detection, identification and quantification of multiclass pesticides in virgin olive oil using liquid chromatography mass spectrometry (LC‐QTOF‐MS). LLE to extract pesticide residues in virgin olive oil was performed in order to study the centrifugation efficiency to obtain high recovery yield and low co‐extract fat residue in the final extract. Different suitable parameters of MSPD procedure were evaluated, such as nature of dispersing phase, clean‐up adsorbent, and volume of eluting solvent (acetonitrile) in different extraction conditions, with or without sonication. The best results were obtained using 5 g of virgin olive oil, 2 g of PSA as dispersant sorbent, 2 g of Florisil/GCB (70:30 w/w) as clean‐up sorbent, and 15 mL of acetonitrile as eluting solvent under conditions of 15 min ultrasonic bath at RT. Method validation was performed in order to study sensitivity, linearity, precision, and accuracy. Average recoveries ranged between 73.7 and 104.2% with relative SDs 5.3–13.4% at three concentration levels (25, 50, and 100 µg/kg). Detection and quantification limits ranged from 1.5 to 5 µg/kg and 3 to 9 µg/kg, respectively. 相似文献
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Sivakumar P. Nagaraju Regonda Samanta Debabrata Sivaram M. Hindia Mhd. Nour Amiri Iraj Sadegh 《Wireless Networks》2020,26(4):2317-2328
Wireless Networks - Nowadays, the smart grid has demonstrated a great ability to make life easier and more comfortable given recent advances. This paper studies the above issue from the perspective... 相似文献
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Altabbaa Mhd. Tahssin Arsan Taner Panayirci Erdal 《Wireless Personal Communications》2019,108(3):1345-1361
Wireless Personal Communications - Femtocell technology is emerging as a key solution for mobile operators for its advantage in coverage and capacity enhancement along with its cost effectiveness.... 相似文献
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Danielson TL Obeidat S Rayson GD Anderson DM Fredrickson EL Estell RE 《Applied spectroscopy》2006,60(7):800-807
Photoluminescence of plant extract solutions has been investigated for discrimination of plant life forms (grasses, forbs, and shrubs) using principal component analysis (PCA). Clippings from each of six plant species representing three different plant life forms potentially found in the diets of free-ranging herbivores in the Chihuahuan Desert of North America were investigated for possible discernment. These plants included Sporobolus flexuosus (mesa dropseed, a grass), Pleuraphis mutica (tobosa, a grass), Dimorphocarpa wislizenii (spectacle pod, a forb), Sphaeralcea incana (pale globemallow, a forb), Flourensia cernua leaves (tarbush, a shrub), and Atriplex canescens leaves and stems (fourwing saltbush, a shrub). Emission spectra (370-600 nm) from phosphate buffered saline (PBS) extract solutions (pH 2.2, 7.5 and 12.5) were recorded for each plant with excitation at 365 nm. Use of PBS minimized chlorophyll interference. Discernment among plant life forms within these plant species was achieved. 相似文献