Effects of dietary casein and soy protein on metabolism of radiolabelled low density apolipoprotein B in rabbits

Rabbits fed semipurified diets containing casein have elevated plasma cholesterol levels compared to those fed soy protein. As part of continuing studies on the mechanism of casein-induced hypercholesterolemia, two groups of six rabbits were fed these diets for 14 to 16 weeks. Animals fed the casein diet were found to have significantly higher plasma concentrations of protein, cholesterol, triacylglycerol, phospholipid and apolipoprotein B (apo B) associated with low density lipoprotein (LDL) than those fed the soy protein diet. Kinetic studies showed that the fractional catabolic rate of LDL-apo B was significantly lower in animals fed casein than in those fed soy protein regardless of whether the tracer LDL was obtained from donors fed casein or soy protein. The production rate of LDL-apo B was higher in casein-fed animals but this was not statistically significant. These results show that the efficiency of removal of LDL is significantly reduced in animals fed casein compared to those fed soy protein, and that the source of LDL did not affect the efficiency of its subsequent removal. The acumulation of LDL in casein-fed animals is consistent with down-regulation of the LDL receptor.     

Changes in zooplankton populations in the White Volta with particular reference to the effect of Abate

The 24‐hour LC 50 of the nauplii of Thermocyclops hyalinus using Abate CE 200 solution was 0.23 ppm., while the 24‐hour LC 50 of both the copepodite and adult stages was 0.2 ppm.

The numbers of drifting zooplanktonic Microcrustacea in the White Volta increased in numbers during the months of March, April, May, June and July in the dry season. The increase in numbers in the post‐sunset samples related to the vertical migration of the zoqplankton in the reservoir upstream. The aerial weekly application of Abate CE 200 solutions at very high lethal concentrations did not seem to affect the Microcrustacea population probably because (a) Microcrustacea drifting into the reservoir from upstream sustained populations in the reservoir; (b) Microcrustacea living at the banks of the reservoir escaped the abate effect flowing downstream; and (c) spraying was done around noon, when the majority of the zooplankton population had migrated to the bottom of the reservoir.     

Effect of vegetarian diets on zinc status: a systematic review and meta‐analysis of studies in humans

Plant‐based diets contain less saturated fat and cholesterol and more folate, fibre and phytochemicals than omnivorous diets, but some micronutrients, especially zinc, are poorly bioavailable. The findings of studies exploring the zinc intake and zinc status in populations that habitually consume vegetarian diets are inconsistent. This study aims to investigate the effects of plant‐based diets on dietary zinc intake and status in humans using systematic review and meta‐analysis techniques. Thirty‐four studies were included in the systematic review. Of these, 26 studies (reporting 48 comparisons) compared males and/or females consuming vegetarian diets with non‐vegetarian groups and were included in meta‐analyses. Dietary zinc intakes and serum zinc concentrations were significantly lower (?0.88 ± 0.15 mg day^?1, P < 0.001 and ?0.93 ± 0.27 µmol L^?1, P = 0.001 respectively; mean ± standard error) in populations that followed habitual vegetarian diets compared with non‐vegetarians. Secondary analyses showed greater impact of vegetarian diets on the zinc intake and status of females, vegetarians from developing countries and vegans. Populations that habitually consume vegetarian diets have low zinc intakes and status. Not all vegetarian categories impact zinc status to the same extent, but a lack of consistency in defining vegetarian diets for research purposes makes dietary assessment difficult. Dietary practices that increase zinc bioavailability, the consumption of foods fortified with zinc or low‐dose supplementation are strategies that should be considered for improving the zinc status of vegetarians with low zinc intakes or serum zinc concentrations at the lower end of the reference range. © 2013 Society of Chemical Industry     

Steel ratios for cost optimum reinforced concrete beams

The amount of main-reinforcement steel in reinforced concrete beams is limited by maximum and minimum steel ratios. No guidance is given by design codes as how to choose the ratios within the permissible range. Using systematic direct search, the influence of various factors on the optimal steel ratio for single-reinforced concrete beams is studied. Using the design code of the American Concrete Institute, it is found that the most influential factors in selection of steel ratios are support conditions and material costs. Applied loads and yield strength of steel are shown to have some influence.     

The role of boron in nutrition and metabolism

A large number of responses to dietary boron occur when the boron content of the diet is manipulated. Numerous studies suggest that boron interacts with other nutrients and plays a regulatory role in the metabolism of minerals, such as calcium, and subsequently bone metabolism. Although the mechanism of action has not been defined, it may be mediated by increasing the concentration of steroid hormones such as testosterone and beta-oestradiol. Boron is obtained from a diet rich in fruits, vegetables, nuts and legumes. The daily intake has been estimated to range from 0.3-41 mg per day. The wide range is due to the variation of the analytical methods used and differences in the soil content of boron. Based on a limited number of studies, increasing dietary boron results in increases in the boron concentration of all tissues. Large amounts of boron are well tolerated while consistent signs of deficiency include depressed growth and a reduction in some blood indices, particularly steroid hormone concentrations. Via its effect on steroid hormones and interaction with mineral metabolism, boron may be involved in a number of clinical conditions such as arthritis. Further research is required before boron is accepted as an essential nutrient for humans.     

LATINFOODS,the Latin American network on food composition

This paper summarizes the history and evolution of the Latin American network on food composition, “LATINFOODS”, and provides information about its main outcomes regarding food composition data in Latin America.     

Three-dimensional virtual-reality surgical planning and soft-tissueprediction for orthognathic surgery

Complex maxillofacial malformations continue to present challenges in analysis and correction beyond modern technology. The purpose of this paper is to present a virtual reality workbench for surgeons to perform virtual orthognathic surgical planning and soft-tissue prediction in three dimensions. A resulting surgical planning system, i.e., three-dimensional virtual reality surgical planning and soft-tissue prediction for orthognathic surgery, consists of four major stages: computed tomography (CT) data post-processing and reconstruction, three-dimensional (3-D) color facial soft-tissue model generation, virtual surgical planning and simulation, soft-tissue-change preoperative prediction. The surgical planning and simulation are based on a 3D CT reconstructed bone model, whereas the soft-tissue prediction is based on color texture-mapped and individualized facial soft-tissue model. Our approach is able to provide a quantitative osteotomy-simulated bone model and prediction of postoperative appearance with photorealistic quality. The prediction appearance can be visualized from any arbitrary viewing point using a low-cost personal computer-based system. This cost-effective solution can be easily adopted in any hospital for daily use     

Preparative gel permeation chromatography of Athabasca asphaltene and the relative polymer-forming propensity of the fractions

Athabasca asphaltene has been separated according to molecular weight on Bio-Beads SX-1 gel. The number-average molecular weights of the five arbitrary fractions obtained by this fractionation range from 1200 to 17000. The chemical, spectral and thermal properties of the fractions are all similar but their polymer-forming propensities are markedly different. The significance of this latter property, which is defined in terms of the amount of CH₂Cl₂-insoluble material produced upon thermolysis at 300 °C, increases rapidly with increasing molecular weight of the fraction. In contrast the whole asphaltene does not form polymer at 300 °C under the same conditions and it is concluded that the chain propagating steps are terminated by a variety of inhibitors that are contained in the asphaltene agglomerate. During gel permeation chromatography separation the clay present in the asphaltene concentrates in the higher-molecular-weight fractions. This affinity to attract the clay is thought to be related to the physical, and not the chemical, properties of these higher-molecular-weight materials. The clay also exerts a catalytic effect on the polymerization of the asphaltene fractions which is most pronounced in the highest-molecular-weight fraction and gradually decreases with decreasing molecular weight.