Urea briquette applicator for transplanted rice

A plunger-type, completely hand-operated applicator prototype, made of polyvinyl chloride (PVC), for deep placement of urea briquettes (UB), i.e., pillow-shaped urea supergranules with edges, in line transplanted rice has been developed for use by small-scale rice farmers. The field evaluation of the applicator was conducted in the Philippines during the 1989 dry season. The applicator consistently placed UB at proper depth (7 to 8 cm), which resulted in low concentrations of urea N (<7 ppm) in about 4 cm of floodwater 1 day after placement. These findings indicated that the prototype worked properly. Average work output of the applicator was 0.20 ha workday^–1 and may increase with practice. The yields of irrigated transplanted rice in the field trials show that agronomic efficiencies of hand-placed UB and applicator-placed UB were equal and were superior to those of split-applied prilled urea.     

Application of the Isolated Perfused Rat Kidney Model to Assess Gender Effects on Drug Excretion

ABSTRACT

Purpose. To study the effect of gender on the renal disposition of two organic anions, p-aminohippuric acid (PAH) and furosemide (FSM) in the isolated perfused rat kidney (IPK). Methods. IPK experiments (3–4 per treatment group) were conducted using kidneys from male and female Sprague Dawley rats. PAH was administered as a continuous infusion (with loading dose, targeted steady-state concentration 10 ug/mL). FSM was added as a bolus dose (2.65 mg, targeted concentration 33 ug/mL). Urine was collected in 10-min. intervals and perfusate was sampled at the midpoint of each collection period. Control (drug naïve) perfusions were performed for both genders. PAH and FSM were measured by HPLC. Kidney viability (GFR [estimated using inulin clearance], sodium reabsorption, glucose reabsorption) was monitored continuously during each perfusion experiment (2-h duration). Results. Good kidney function was maintained across all study groups, and lower GFR estimates in female kidneys were due to differences in kidney weight. For PAH, kidney weight corrected renal clearance (0.88 ± 0.37 mL/min/g vs. 0.59 ± 0.19 mL/min/g) and excretion ratio (3.8 ± 1.7 vs. 2.2 ± 0.72) were significantly higher in male kidneys. For FSM, renal clearance was significantly lower in female (0.10 ± 0.05 mL/min/g) compared to male kidneys (0.15 ± 0.07 mL/min/g). Mass balance analysis showed that FSM cumulative urinary excretion was significantly higher and kidney accumulation was significantly lower in experiments with male kidneys. Conclusions. The study demonstrates that the IPK is a useful model to assess gender effects on renal drug disposition. The renal excretion of organic anions is reduced in female rats, possibly due to gender differences in expression and/or activity of membrane transporters (both basolateral and luminal) in the kidney.     

Effect of amounts and sequence of additions of urea and water on hydrolysis of surface-applied granular urea in unsaturated soils

The hydrolysis of surface-applied granular urea ( 15 mg of urea/particle) in 14 unsaturated soils as influenced by the amounts and the sequence of additions of urea and water and studied using open and covered soil column systems was in the following order: well-mixed surface-applied surface-applied surface-applied urea, granular urea, granular urea, granular urea, water added > water added > water added water added before, after, before, before, no drying no drying no drying drying The retarded hydrolysis' of surface-applied granular urea is attributed to retarded soil urease activity. Under the nondrying and drying conditions, the positive effect of increasing amounts of added water on the hydrolysis was less apparent when water was added 24–48 hours before than when it was added immediately after surface application of granular urea. When an increasing number of urea granules were evenly placed on a finite surface of unsaturated soil, the rate of urea application (quantity factor) increased but the percentage of urea hydrolyzed remained practically unchanged. These results suggest that it is necessary to consider effective urea concentration and effective urease activity for adequate understanding of in situ hydrolysis of broadcast fertilizer urea in unsaturated soil.     

Application of the isolated perfused rat kidney model to assess gender effects on drug excretion

PURPOSE: To study the effect of gender on the renal disposition of two organic anions, p-aminohippuric acid (PAH) and furosemide (FSM) in the isolated perfused rat kidney (IPK). METHODS: IPK experiments (3-4 per treatment group) were conducted using kidneys from male and female Sprague Dawley rats. PAH was administered as a continuous infusion (with loading dose, targeted steady-state concentration 10 ug/mL). FSM was added as a bolus dose (2.65 mg, targeted concentration 33 ug/mL). Urine was collected in 10-min. intervals and perfusate was sampled at the midpoint of each collection period. Control (drug na?ve) perfusions were performed for both genders. PAH and FSM were measured by HPLC. Kidney viability (GFR [estimated using inulin clearance], sodium reabsorption, glucose reabsorption) was monitored continuously during each perfusion experiment (2-h duration). RESULTS: Good kidney function was maintained across all study groups, and lower GFR estimates in female kidneys were due to differences in kidney weight. For PAH, kidney weight corrected renal clearance (0.88 +/- 0.37 mL/min/g vs. 0.59 +/- 0.19 mL/min/g) and excretion ratio (3.8 +/- 1.7 vs. 2.2 +/- 0.72) were significantly higher in male kidneys. For FSM, renal clearance was significantly lower in female (0.10 +/- 0.05 mL/min/g) compared to male kidneys (0.15 +/- 0.07 mL/min/g). Mass balance analysis showed that FSM cumulative urinary excretion was significantly higher and kidney accumulation was significantly lower in experiments with male kidneys. CONCLUSIONS: The study demonstrates that the IPK is a useful model to assess gender effects on renal drug disposition. The renal excretion of organic anions is reduced in female rats, possibly due to gender differences in expression and/or activity of membrane transporters (both basolateral and luminal) in the kidney.     

Efficient Implicit Finite-Element Hydrodynamic Model for Dam and Levee Breach

This technical paper presents the development and application of a pseudo-transient continuation (PTC)– inspired flow model for the simulation of dam and levee failure. The unstructured, implicit, Petrov-Galerkin finite-element model relies on computed residuals to automatically adjust the time-step size. The implicit time integration, together with the automatic time-step size selection through PTC, makes the model computationally efficient. The model is verified and applied to several analytic and real-world test cases that exercise model behavior and accuracy for several critical, transcritical, and subcritical flows. The result is an efficient and accurate prediction of both the speed and depth of shock waves as the dam-break flow passes over initially dry and wet land.     

Mutual injection locking: a new architecture for high-power solid-state laser arrays

In this paper, bidirectional (mutual) injection locking is demonstrated with solid-state lasers, producing significant improvements over traditional single-direction injection locking. Each laser element shares part of its output with other elements in bidirectional locking, distinct from single-direction (traditional) injection locking where one master laser provides the locking signal for a number of slaves. In a phase-locked array, the individual laser outputs add coherently, and the brightness of the entire array scales with the square of the number of elements, as if the active material diameter were increasing. Benefits of bidirectional locking, when compared to traditional injection locking, include reduced laser threshold, better output beam quality, and improved scaling capability. Experiments using two Nd:YVO/sub 4/ lasers confirmed that mutual injection locking reduced lasing threshold by a factor of at least two and increased the output beam quality significantly. The injection-locking effects began with 0.03% coupling between lasers and full-phase locking for coupling exceeding 0.5%. The 0.5% requirement for full-phase locking is significantly lower than the requirement for traditional injection locking. The large coupling requirement limits traditional injection-locked arrays to fewer than 20 elements, whereas mutually injection-locked arrays have no such limit. Mutual injection locking of an array of lasers can lead to a new architecture for high-power laser systems.     

Application of Methanobrevibacter acididurans in anaerobic digestion.

To operate anaerobic digesters successfully under acidic conditions, hydrogen utilizing methanogens which can grow efficiently at low pH and tolerate high volatile fatty acids (VFA) are desirable. An acid tolerant hydrogenotrophic methanogen viz. Methanobrevibacter acididurans isolated from slurry of an anaerobic digester running on alcohol distillery wastewater has been described earlier by this lab. This organism could grow optimally at pH 6.0. In the experiments reported herein, M. acididurans showed better methanogenesis under acidic conditions with high VFA, particularly acetate, than Methanobacterium bryantii, a common hydrogenotrophic inhabitant of anaerobic digesters. Addition of M. acididurans culture to digesting slurry of acidogenic as well as methanogenic digesters running on distillery wastewater showed increase in methane production and decrease in accumulation of volatile fatty acids. The results proved the feasibility of application of M. acididurans in anaerobic digesters.     

Urea briquettes containing diammonium phosphate: a potential new NP fertilizer for transplanted rice

The rapid rise in fertilizer prices over the past 2 years coupled with the notoriously low nutrient recovery of fertilizer by lowland rice as managed by farmers of most developing countries has prompted a re-examination of urea briquette agrotechnology that improves fertilizer use efficiency.Urea briquettes containing diammonium phosphate (UB-DAP) can be cost effectively produced using a portable fertilizer briquetter on a small scale (200 kg^-1 h^-1) at the village level and at a price affordable by small rice farmers. Their improved management consists of hand placement of properly sized (weight) UB-DAP (N:P = 4:1) per briquette for every four rice hills, and at 7–10 cm soil depth, on the day of or the day after transplanting using modified 20 × 20 cm spacing (25 hills m^-2). This management is simple to adopt, saves up to 50% of the labor normally required for its conventional hand placement, and helps to reduce the lag period of spatial nonavailability of DAP-P to the rice plants. Results of several farmer-managed field trials conducted during the 1990–95 wet seasons in India demonstrate that the UB-DAP management makes the fertilizer agronomically more efficient, economically more attractive with less risk, and reduced losses of nutrients as compared with conventional use of prilled urea and single superphosphate. The fertilizer use offers women farmers a unique opportunity to play an important role in increasing rice productivity. The management of UB-DAP can be integrated with plant nutrient recycling and limited Gliricidia green manuring (an agroforestry approach). This integrated use of UB-DAP has the potential to increase rice production of small resource-poor rice farmers with less fertilizer and in sustainable manner in rainfed as well as irrigated transplanted rice ecoregions of developing countries, while protecting the environment. Therefore, the UB-DAP fertilizer can be an important NP source for transplanted rice in the 21^st century.     

Agronomic performance of urea briquette applicator in transplanted rice

Field trials were conducted in the Philippines and India during 1989 and 1990 seasons to study comparative yield responses of transplanted rice (Oryza sativa L.) to pillow-shaped urea briquettes (UB) deep placed by an applicator (prototype developed by IFDC) and by hand immediately after transplanting. The applicator-placed UB consistently increased grain yields over the split-applied prilled urea, and the additional yields ranged from 0.23 to 1.48t ha^–1 (5 to 83%) for 25 to 63 kg N ha^–1. Agronomic responses of transplanted rice to the UB placed by the applicator and by hand were statistically equal. Modified rice hill spacing may be considered as a requirement for efficient use of the applicator. The results demonstrate that with the UB applicator it is possible to deep place UB mechanically and achieve the agronomic efficiency that is achieved by hand deep placement of the UB.