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排序方式: 共有259条查询结果,搜索用时 468 毫秒
1.
Juana Maria de Lourdes Medina-Contreras Patrick Mailloux-Salinas Juventino III Colado-Velazquez Norma Leticia Gomez Viquez Gómez-Viquez Rodrigo Velázquez-Espejel Ana del Carmen Susunaga-Notario David Julian Arias-Chávez Guadalupe Bravo 《Journal of the science of food and agriculture》2020,100(7):3212-3219
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George Grant Fiona Greer Norma H. McKenzie Arpad Pusztai 《Journal of the science of food and agriculture》1985,36(5):409-414
In a series of 10-day pair feeding experiments it was found that the nutritional value of diets containing beans was essentially the same for rats aged between 30 and 123 days. Thus net protein utilisation (NPU) values of 25–39 on diets containing Processor bean (35 g protein kg?1) + egg albumin (65g protein kg?1) were obtained. As food intakes were considerably reduced when rats were fed diets containing more than 35g protein kg?1 of Processor bean, the measurement of protein utilisation became increasingly more difficult. The severe disruption of the brush borders of duodenal and jejunal enterocytes, originally observed when bean-containing diets were fed to young (30-day-old) rats was also found with rats up to the age of 120 days on similar diets. Similarly, the development of circulating anti-lectin antibodies in the animals showed no age dependence within the age limits investigated. It was also shown that oral immunisation did not protect the rats from the effects of toxicity and that the immune response was a result of continuous absorption of lectin throughout the feeding period. Thus the extent and the mechanism of toxicity of Phaseolus vulgaris bean lectins were found not to be dependent on the age or maturity of the animal. 相似文献
4.
Isabel Vega Emiliano Fernández Carmen Mijangos Norma D'Accorso Daniel López 《应用聚合物科学杂志》2008,110(2):695-700
The authors report on the viscoelastic characterization of guar hydrogels obtained through complexation reactions with borax ions. These gels are compared with hydrogels obtained from poly(vinyl alcohol) of different degree of hydrolysis through complexation reactions with congo red. The effect of the degree of hydrolysis and both, the concentration of PVA and the concentration of congo red, on the viscoelastic properties of the hydrogels is analyzed. The potential use of the PVA‐based hydrogels as hydraulic fracturing liquids is discussed in relation to the commonly used fracturing liquid based on the guar–borax system. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 相似文献
5.
Luis Armando Rosas Rivera Norma F. Hubele PhD Frederick P. Lawrence PhD 《Computers & Industrial Engineering》1995,29(1-4):55-58
Process capability indices (PCIs) are used in industry to assess percentages of nonconforming parts. An underlying assumption is that the output process measurements are distributed as normal random variables. When normal distributions are assumed, but different distributions are present - such as skew, heavy-tailed, and short-tailed distributions - the percentages of nonconforming parts are significantly different than the computed PCIs indicate. Data arising from nonnormal distributions can sometimes be transformed to conform to the normality assumption and the PCI's computed for the transformed data. In this paper, the effect of the transformation on the estimate of nonconforming parts is examined for three examples of nonnormal distributions - gamma, lognormal, and Weibull. The results of this experimental analysis suggest that data transformation can be useful for estimating an interval for Cpk values and the number of nonconforming parts. 相似文献
6.
This article examines the popular claim of Content Management Systems (CMSs) that providing a rich toolset and leaving the use under learner control is beneficial to learning. By means of a literature review, the current contribution examines whether all students are capable of using CMS tools so that their learning is enhanced. In contrast to what is assumed, the study conceptualizes tool use as a complex self-regulation strategy that cannot be taken for granted. Specifically, the article reviews empirical studies in relation to three topics: (a) personal agency in tool use, (b) performance effects of tool use and (c) influencing tool use variables. Findings reveal that not every student profited from the CMS learning opportunities; in multiple studies students differed in their tool use, and these differences had significant performance effects. Hence, these findings suggest that the pedagogical claim CMSs make is problematic. Besides this accumulated corpus of knowledge, the review revealed serious limitations in the retrieved studies which could hamper our findings. As a consequence, the review establishes a need for further research into students’ CMS tool use from an instructional design perspective. In addition to the theoretical framework, several directions for future research are given. 相似文献
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Andrea Snchez-Navarro Miguel ngel Martínez-Rojas Adrin Albarrn-Godinez Rosalba Prez-Villalva Johan Auwerx Abigail de la Cruz Lilia G. Noriega Florencia Rosetti Norma A. Bobadilla 《International journal of molecular sciences》2022,23(5)
Acute kidney injury (AKI) is a public health problem worldwide. Sirtuins are a family of seven NAD+-dependent deacylases, Overexpression of Sirtuin 1, 3, and 5 protect against AKI. However, the role of Sirtuin 7 (Sirt7) in AKI is not known. Here, we analyzed how Sirt7 deficient mice (KO-Sirt7) were affected by AKI. As expected, wild-type and Sirt7 heterozygotes mice that underwent renal ischemia/reperfusion (IR) exhibited the characteristic hallmarks of AKI: renal dysfunction, tubular damage, albuminuria, increased oxidative stress, and renal inflammation. In contrast, the KO-Sirt7+IR mice were protected from AKI, exhibiting lesser albuminuria and reduction in urinary biomarkers of tubular damage, despite similar renal dysfunction. The renoprotection in the Sirt7-KO+IR group was associated with reduced kidney weight, minor expression of inflammatory cytokines and less renal infiltration of inflammatory cells. This anti-inflammatory effect was related to diminished p65 expression and in its active phosphorylation, as well as by a reduction in p65 nuclear translocation. Sirt7 deficient mice are protected from AKI, suggesting that this histone deacetylase promotes tubular damage and renal inflammation. Therefore, our findings indicate that Sirt7 inhibitors may be an attractive therapeutic target to reduce NFκB signaling. 相似文献
9.
María L Auad Tara Richardson William J Orts Eliton S Medeiros Luiz HC Mattoso Mirna A Mosiewicki Norma E Marcovich Mirta I Aranguren 《Polymer International》2011,60(5):743-750
Segmented polyurethanes exhibiting shape memory properties were modified by the addition of polyaniline (PANI)‐coated cellulose nanofibrils (CNFs). The two‐phase structure of the polymer is responsible for the material's ability to ‘remember’ and autonomously recover its original shape after being deformed in response to an external thermal stimulus. PANI was grown on the surface of the CNFs via in situ polymerization. Modified nanocrystals were added to the segmented polyurethane in concentrations ranging from 0 to 15 wt%. The changes in the material properties associated with the percolation of the coated fibrils appear at higher concentrations than previously observed for non‐modified CNFs, which suggests that fibril agglomeration is occurring due to the PANI coating. The shape memory behavior of the composites is maintained at about the same level as that of the unfilled polyurethane only up to 4 wt% of fibrils. At higher concentrations, the rigidity of the nanofibrils as well as their interaction with the hard‐segment phase and the increasing difficulty of dispersing them in the polymer collaborate to produce early breakage of the specimens when stretched at temperatures above the melting point of the soft segments. Copyright © 2010 Society of Chemical Industry 相似文献
10.
Tharinger Deborah J.; Lambert Nadine M.; Bricklin Patricia M.; Feshbach Norma; Johnson Neal F.; Oakland Thomas D.; Paster Vera S.; Sanchez William 《Canadian Metallurgical Quarterly》1996,27(1):24
National, state, and local education reform agendas have been on a fast track for more than a decade. Although some psychologists have been active in promoting psychology and psychological services in education reform initiatives, knowledge about their efforts is fragmented. In order to educate psychologists about education reform, this article highlights the impetus for the recent education reform movement, briefly reviews the latest waves of education reform, and discusses the development of the National Education Goals. Then, an argument is made for the integration of education, health, and social reform initiatives; state-level education reform principles and initiatives are highlighted, illustrated by the systemic education reform mandate in Kentucky. Next, progress toward the development and implementation of an APA-sponsored response to the National Education Goals is discussed. Finally, objectives and roles for psychologists in advancing education reform are presented, and guidelines for the education and training of future psychologists are introduced. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献