Balanced corpus of contemporary written Japanese

The balanced corpus of contemporary written Japanese (BCCWJ) is Japan’s first 100 million words balanced corpus. It consists of three subcorpora (publication subcorpus, library subcorpus, and special-purpose subcorpus) and covers a wide range of text registers including books in general, magazines, newspapers, governmental white papers, best-selling books, an internet bulletin-board, a blog, school textbooks, minutes of the national diet, publicity newsletters of local governments, laws, and poetry verses. A random sampling technique is utilized whenever possible in order to maximize the representativeness of the corpus. The corpus is annotated in terms of dual POS analysis, document structure, and bibliographical information. The BCCWJ is currently accessible in three different ways including Chunagon a web-based interface to the dual POS analysis data. Lastly, results of some pilot evaluation of the corpus with respect to the textual diversity are reported. The analyses include POS distribution, word-class distribution, entropy of orthography, sentence length, and variation of the adjective predicate. High textual diversity is observed in all these analyses.     

Microstructure of ion-implanted region in TiNi alloy

TiNi alloy samples implanted with various fluences of 3 MeV Cu²⁺ ions were characterized by transmission electron microscope (TEM) and X-ray diffractometer. Cross-sectional TEM images of the samples showed that amorphous region was seen at the fluence of 10¹⁴ ions cm^?2 in case of ion implantation at 300 K of the substrate temperature, but in case of ion implantation at 100 K it did not appear even at 10¹⁵ ions cm^?2. These results were also confirmed by X-ray diffraction profiles of the same samples. Consequently, the extent of microstructure change of TiNi alloy by ion implantation was different depending on the substrate temperature.     

In Vitro and in Vivo Characteristics of Fluorapatite-Forming Calcium Phosphate Cements

This study reports for the first time in vitro and in vivo properties of fluorapatite (FA)-forming calcium phosphate cements (CPCs). The experimental cements contained from (0 to 3.1) mass % of F, corresponding to presence of FA at levels of approximately (0 to 87) mass %. The crystallinity of the apatitic cement product increased greatly with the FA content. When implanted subcutaneously in rats, the in vivo resorption rate decreased significantly with increasing FA content. The cement with the highest FA content was not resorbed in soft tissue, making it the first known biocompatible and bioinert CPC. These bioinert CPCs might be useful for applications where slow or no resorption of the implant is required to achieve the desired clinical outcome.     

Dielectric function and the crystal structure of MeV ion implanted LiNbO3

The behavior of the dielectric functions of MeV ion-implanted LiNbO₃ was studied using THz spectroscopy. Single crystal LiNbO₃ specimens were implanted with 3 MeV Au ions at four different levels of ion fluence (1 × 10¹², 1 × 10¹³, 1 × 10¹⁴ and 1 × 10¹⁵ cm^− 2). The optical spectra of the specimens were then measured in two ranged values: (1) reflectance THz range spectra from 40 to 700 cm^− 1 and (2) reflectance ultraviolet, visible, and near-infrared spectra from 250 to 2000 nm. The THz spectra were analyzed by fitting with the dielectric function model proposed by Brendel. The dielectric function model explained well the experimental spectra of the ion-implanted LiNbO₃. The dielectric function shows that the ion-implanted layers were amorphous phase at the fluence of 1 × 10¹⁴ and 1 × 10¹⁵ cm^− 2, whereas the layers at 1 × 10¹² and 1 × 10¹³ cm^− 2 maintained the crystal phase but significantly suppressed the phonon resonances. The volume of ion-implanted layers expanded about 8% with the fluence of 1 × 10¹⁴ and 1 × 10¹⁵ cm^− 2, i.e. after amorphization, These results show that the ion implantation significantly affected the lattice vibration mode and the structure even at very low ion fluence.     

Analysis of cracks in aging aircraft structures,with and without composite-patch repairs

In this paper, the problems of composite-patch repair of (i) center and edge-cracked panels loaded in the far-field; and (ii) cracks emanating from pin-loaded fastener holes, are examined in thorough detail. The effects of various non-dimensional design parameters on the reduction in the stress-intensity factors near the crack-tip are determined, and are presented in the form of design charts. Both analytical and numerical methods are employed in this study. In the analytical method, the cracked metallic plate was considered to be infinitely large, and the composite patch was modeled as a long orthotropic strip of finite height (in the direction perpendicular to the crack axis). Next, by using the Finite Element Alternating Method (FEAM), a more general analysis capability that can treat arbitrary shapes of the cracked metallic sheet, as well as of the composite patches, is developed. This general FEAM is applied to: (i) composite patch repairs of cracks emanating from loaded fastener holes (the MSD problem); (ii) composite patch repairs of semi-elliptical surface flaws in thick plates; and (iii) composite patch repairs of quarter-elliptical surface flaws emanating from fastener holes. Problem (i) is two-dimensional in nature while problems (ii) and (iii) are fully three-dimensional. In all these cases, the effects of various design parameters on the crack-tip (front) stress-intensity factors are fully discussed.     

Curvature-based residual stress measurement for ion-implanted stainless-steel sheet

Residual stress in ion-implanted stainless-steel sheet and the effects of ion species and implantation dose on the residual stress were investigated by using curvature technique based on the Stoney equation. Six species of ions of Au, Ag, Fe, Ni, Ti and Si were implanted into the stainless steel sheet with an energy of at the dose of 1.0×10¹⁶ to . The depth profile of the ion implantation in the ion-implanted layer was examined by using transmission electron microscopy equipped with an energy-dispersive X-ray spectroscopy. The level of the residual stress evaluated by the Stoney equation was compared with the results of X-ray diffraction.     

A sensitive analytical method for six aflatoxins in rainbow trout muscle and liver

A highly sensitive analysis method for six aflatoxins (aflatoxin B?, B?, G?, G?, M? and aflatoxicol) in rainbow trout muscle and liver was developed. Aflatoxins (AFs) were extracted with acetonitrile-water (9 : 1), purified on an immunoaffinity column, and subjected to HPLC with fluorescence detection after post-column photochemical derivatization. The recoveries of AFs at 0.05 μg/kg spiking levels were 71.4-82.4% in muscle and 80.1-93.0% in liver, and the repeatability relative standard deviations (RSDr) were 0.87-4.6% in muscle and 2.0-6.2% in liver. Limits of quantitation (LOQs) and limits of detection(LODs)of AFs were estimated to be 0.004-0.029 μg/kg, and 0.002-0.012 μg/kg, respectively.     

Enhancement of the oral bioavailability of phenytoin by N-acetylation and absorptive characteristics

To improve the absorbability of phenytoin (DPH), a prodrug, N-acetyl-DPH (EDPH), was synthesized, and the absorptive characteristics and pharmacokinetics of the prodrug were evaluated in rats. EDPH was rapidly hydrolyzed to DPH in the intestinal fluid and the mucosa (rate constant, 0.055 and 0.169 min(-1), respectively). The plasma concentrations of DPH after intravenous dosing of EDPH declined in a biexponential manner, although two different elimination patterns were observed in these rats. When dosed orally (25 mg/kg, DPH equivalent), the plasma levels of DPH converted from the prodrug were significantly higher and more sustained than those after DPH alone, giving bioavailability 11.4 (rapid decay) and 9.1 times (slow decay) as high, respectively, as that after DPH alone. The concentrations of DPH distributed into the mucosa of the duodenum and jejunum 1 and 5 h after oral dosing of EDPH were significantly higher than those after DPH alone. The prodrug and DPH converted from the prodrug dissolved 2-4 fold more than DPH alone in bile salt solution and bile salt-oleic acid mixed micelles, indicating the increased solubility of the prodrug in the intestinal fluid. It is concluded from the data that such high solubility of EDPH enhanced the intestinal absorption of the prodrug, part of which would be absorbed in the amide form, and thus gave the high bioavailability.