The solutions of the spherically symmetric, linear, isothermal, and transient viscoelasticity problems via reciprocity theorem have been investigated for a specific material. The integral form of stress–strain relations has been used. The Laplace transform of a viscoelastic state, which is necessary for the integral equation arising as a result of reciprocity theorem, has been derived. This integral equation has been solved by Laplace transform. A sample problem has been solved to test the presented formulation. A numerical application of the analytic solution of this problem has been given. 相似文献
The high-speed response properties of resonant cavity enhanced (RCE) photodetectors have been investigated. The limitations on the high-speed performance of photodiodes and the advantages of RCE-detection are discussed. Transient response of heterojunction photodiodes under pulsed optical illumination has been simulated using the method described in Part I. Results on conventional AlGaAs/GaAs and RCE GaAs/InGaAs heterojunction p-i-n photodiodes are presented. For small area detectors, almost 50% bandwidth improvement along with a two-fold increase in efficiency is predicted for RCE devices over optimized conventional photodiodes. A nearly three-fold enhancement in the bandwidth-efficiency product was shown 相似文献
With the introduction of the Regular Membership Constraint, a new line of research has opened where constraints are based
on formal languages. This paper is taking the next step, namely to investigate constraints based on grammars higher up in
the Chomsky hierarchy. We devise a time- and space-efficient incremental arc-consistency algorithm for context-free grammars,
investigate when logic combinations of grammar constraints are tractable, show how to exploit non-constant size grammars and
reorderings of languages, and study where the boundaries run between regular, context-free, and context-sensitive grammar
filtering. 相似文献
Pigeon Pea (Cajanus cajan (L.) Millsp.) is a common food crop used in many parts of the world for nutritional purposes. One of its chemical constituents is cajanin stilbene acid (CSA), which exerts anticancer activity in vitro and in vivo. In an effort to identify molecular targets of CSA, we performed a kinome-wide approach based on the measurement of the enzymatic activities of 252 human kinases. The serine-threonine kinase WNK3 (also known as protein kinase lysine-deficient 3) was identified as the most promising target of CSA with the strongest enzymatic activity inhibition in vitro and the highest binding affinity in molecular docking in silico. The lowest binding affinity and the predicted binding constant pKi of CSA (−9.65 kcal/mol and 0.084 µM) were comparable or even better than those of the known WNK3 inhibitor PP-121 (−9.42 kcal/mol and 0.123 µM). The statistically significant association between WNK3 mRNA expression and cellular responsiveness to several clinically established anticancer drugs in a panel of 60 tumor cell lines and the prognostic value of WNK3 mRNA expression in sarcoma biopsies for the survival time of 230 patients can be taken as clues that CSA-based inhibition of WNK3 may improve treatment outcomes of cancer patients and that CSA may serve as a valuable supplement to the currently used combination therapy protocols in oncology. 相似文献
The creep behavior of high-density polyethylene has been studied by low compressive creep tests, and empirical results were analyzed and compared with analytically predicted results. The tests are performed upon ASTM standard specimens at various stress levels in the linear region. After these analyses, a mathematical model is derived and used to predict creep strain for long periods of time from the strain-time data obtained at different stresses over a time interval of 24 h. 相似文献
We describe a new method of sensing the linear polarization of light using resonant cavity enhanced (RCE) photodetectors. The RCE detectors are constructed by integrating a thin absorption region into an asymmetric Fabry-Perot cavity. The top reflector is formed by the semiconductor air interface while the bottom mirror is a distributed Bragg reflector (DBR). Quantum efficiency of these RCE devices can be controlled by tuning the cavity length by recessing the top surface of the detector for off-normal incidence of light the reflectivity of the semiconductor-air interface can be significantly different for TE(s) and TM(p) polarizations. A pair of monolithically integrated RCE photodetectors with cavity lengths tuned for resonance and antiresonance provide a large contrast in response to TE and TM polarizations. An alternative polarization sensor can be formed by vertically integrating a conventional and a RCE photodetector. We show that a large contrast in the TE/TM responsivities of the vertical cavity polarization detectors (VCPD) can be achieved, thus combining detection and polarization sensing in a single mesa semiconductor device. These devices alleviate the problems associated with the bulkiness and critical alignment constraints of the conventional sensors based on polarizing filters or splitters and have potential for fabrication of monolithic smart pixels and imaging arrays 相似文献
The shear stress–strain behaviour of two low-modulus structural adhesives has been measured using the butt-torsion test. The Nadai correction for non-linear shear behaviour is explained as it is necessary to understand how this correction can be applied to butt joints. The results for one adhesive were accurately used to predict the strength of a lap joint, and it was shown that the strength of such a joint can approach that of a conventional, modern, structural epoxy. Structural adhesives are usually reckoned to be those with a high strength (50 MPa and upwards) and (these days), a strain to failure of at least 10% in tension, and which usually have a tensile modulus of 2 GPa or so. However, adhesives which are significantly less stiff, less strong, but much more ductile are entering the ‘structural’ arena. In order to evaluate their effectiveness and use in design, it is necessary to be able to measure accurately their stress–strain behaviour. Two such materials are 3M 9245 Structural Bonding Tape (SBT) and 3M 7838 B/A. 相似文献
Resonant cavity enhanced (RCE) photodiodes (PD's) are promising candidates for applications in optical communications and interconnects where high-speed high-efficiency photodetection is desirable. In RCE structures, the electrical properties of the photodetector remain mostly unchanged; however, the presence of the microcavity causes wavelength selectivity accompanied by a drastic increase of the optical field at the resonant wavelengths. The enhanced optical field allows to maintain a high efficiency for faster transit-time limited PD's with thinner absorption regions. The combination of an RCE detection scheme with Schottky PD's allows for the fabrication of high-performance photodetectors with relatively simple material structures and fabrication processes. In top-illuminated RCE Schottky PD's, a semitransparent Schottky contact can also serve as the top reflector of the resonant cavity. We present theoretical and experimental results on spectral and high-speed properties of GaAs-AlAs-InGaAs RCE Schottky PD's designed for 900-nm wavelength 相似文献
Anti-slip control systems are essential for railway vehicle systems with traction. In order to propose an effective anti-slip control system, adhesion information between wheel and rail can be useful. However, direct measurement or observation of adhesion condition for a railway vehicle in operation is quite demanding. Therefore, a proportional–integral controller, which operates simultaneously with a recently proposed swarm intelligence-based adhesion estimation algorithm, is proposed in this study. This approach provides determination of the adhesion optimum on the adhesion-slip curve so that a reference slip value for the controller can be determined according to the adhesion conditions between wheel and rail. To validate the methodology, a tram wheel test stand with an independently rotating wheel, which is a model of some low floor trams produced in Czechia, is considered. Results reveal that this new approach is more effective than a conventional controller without adhesion condition estimation.
[3H]Quinuclidinyl benzilate binding properties of cerebral cortex, hippocampus, hypothalamus and brainstem of rats subjected to transient forebrain ischemia or severe hemorrhagic shock were investigated. Maximal binding capacities (Bmax) were not significantly different from control animals in either model. On the other hand, significant increases in binding affinities at all four brain regions in the ischemia-reperfusion group and at hypothalamic and brainstem membranes in the hemorrhagic shock group were observed. Kd values obtained in cortex and hippocampus of animals in shock were similar to control values. It was concluded that in brain ischemia models, the number of brain muscarinic receptors do not change at early stages, but binding affinities increase most likely due to systemic hypotension rather than reperfusion. The well-developed circle of Willis seems to protect cortical and hippocampal muscarinic receptors from hypoxia-induced changes. 相似文献