The function of the reproductive system in x-ray-irradiated male rats after the transplantation of a culture of testicular cells from newborn piglets

The effect exerted by transplantation of the 5 day culture of testicles from newly born piglets on the hypogonadal state of mature X-ray irradiated (3 Gy) rats was studied. It has been found that a month after transplantation (two months after irradiation) the hypogonadal state disappeared for a while, which is confirmed by normalization of the weight of seminal vesicles, content of testosterone and biologically active lutropine, restoration of the reproductive function of rats. No significant changes in steroidogenesis activity have been found, which proves a substituent character of transplantation. The effect disappears three months later but certain restoration of the content of nucleic acids in the testicles is observed.     

A machine learning system for identifying transmembrane domains from amino acid sequences

We present our machine learning system, that uses inductive logic programming techniques to learn how to identify transmembrane domains from amino acid sequences. Our system facilitates the use of operators such as ‘contains’, that act on entire sequences, rather than on individual elements of a sequence. The prediction accuracy of our new system is around 93%, and this compares favourably with earlier results. This work was carried out with the support of a research grant from ISIS, Fujitsu Laboratories.     

电阻-时间线性转换电路

基于电阻的传感器,如应力规和压阻器件,常用于测量多种物理参数.对于使用数字处理器或微控制器进行数据采集和信号处理的设备来说,传感器的响应必须表现为一种适合于转换成数字格式的形式.把这类传感器的电阻变化转换成一个与之成比例的频率或时间间隔是可取的,所以你就能用一个计数器或定时器来方便地得到数字形式的输出信号.图1所示电路把传感器的电阻RS线性地转换成与之成比例的时间间隔.这一电路实际上是一个张驰振荡器,由一个电流源、一个桥式放大器、一个比较器和一个触发器组成.电流IS分成两路,分别通过R1和R2,就如同这两个电阻并联在一起一样.假定运算放大器是理想放大器,则当RX(R4+RS)大于R1R3/R2时,该电路就起一个振荡器的作用.     

Fine needle aspiration cytologic findings in malignant small cell tumor of the thoracopulmonary region (Askin tumor)

From 1980 to 1992, five cases of Askin tumor were diagnosed by fine needle aspiration cytology at the Shiraz University Hospitals, Namazi, Faghihi and Beheshti, Iran. All patients were female, their ages ranging between 15 and 22 years. Three of them had a mass on the right side and two on the left side of the chest. Chest roentgenography revealed no bone involvement. Two tumors involved the lungs and pleura. Urinary catecholamine levels were within normal limits. The fine needle aspiration smears revealed many small, round malignant cells with indistinct cytoplasm, a high nuclear/cytoplasmic ratio and prominent, multiple nucleoli. Homer-Wright rosettes were seen frequently. The cells were often arranged in rows simulating rouleaux formation. They were positively stained by periodic acid-Schiff stain. The histologic sections confirmed the cytologic diagnosis of Askin tumor. Four of the patients died within 7-11 months after treatment began.