Facile fabrication of elongated polymer micro/nano discs and their surface adhesiveness

The key factor of polymer particles using as a drug carrier is the ability to adhere to the surface of the target sites in order to optimize the drug delivery efficiency. To this end, shape of the particles is one of the essential parameters since nonspherical particles such as discs theoretically have more contact surface area than spherical particles. We herein propose a facile method to fabricate elongated polymer micro/nano discs by combining phase separation and a roll-to-roll coating process with a stretching method. By roll-to-roll coating, biodegradable poly(lactide-co-glycolide) (PLGA) discs formed on polyvinyl alcohol (PVA) film can be instantly stretched by uniaxial stretcher. The effect of stretching temperature and percentage of film elongation on the particle morphology was studied. The results showed that the PLGA discs can be elongated and the aspect ratio of 2.3 can be achieved with 600% elongation at 80°C, reflecting the increase of estimated contact surface area by 1.8 times. The adhesion efficiency of these elongated discs was compared with discs before stretching, spheres, and elongated spheres by using the water-dropping test. The elongated discs showed the best result among these particles and their adhesion efficiency are strongly related to estimated contact surface area.     

Adsorption and diffusion of light alkanes on nanoporous faujasite catalysts investigated by molecular dynamics simulations

Molecular dynamics simulations were performed for ethane, propane, and n-butane in siliceous faujasite for different numbers of molecules per unit cell (loadings) at 300 K. Both the adsorbed molecules and the zeolite framework were modeled as flexible entities. A new semiempirical analytical potential function for the systems was constructed. From the mean-square displacement of the molecules, self-diffusion coefficients of 18.7 × 10⁻⁵, 13.3 × 10⁻⁵, and 4.3 × 10⁻⁵ cm²/s were calculated for ethane, propane, and n-butane, respectively at a loading of 8 molecules/unit cell. They compare well with experimental values from pulsed-field gradient NMR measurements (10 × 10⁻⁵, 9 × 10⁻⁵, and 6 × 10⁻⁵ cm²/s, respectively). Besides depending on the size of the hydrocarbon, the heats of adsorption and self-diffusion coefficients also strongly depend on the loading of adsorbate molecules. The results suggest that the new intermolecular force field can reasonably describe the adsorption and diffusion behavior of ethane, propane, and n-butane in faujasite zeolite.     

Influences of the phenolic curative content and blend proportions on the properties of dynamically vulcanized natural rubber/acrylonitrile–butadiene–styrene blends

The vulcanization of natural rubber (NR)‐blended acrylonitrile–butadiene–styrene (ABS) was carried out with a phenolic curing agent by a melt‐mixing process. The NR compound was first prepared before blending with ABS. The effects of the phenolic curative contents (10, 15, and 20 phr) and blend proportions (NR/ABS ratio = 50 : 50, 60 : 40, and 70 : 30) on the mechanical, dynamic, thermal, and morphological properties of the vulcanized NR/ABS blends were investigated. The tensile strength and hardness of the blends increased with increasing ABS content, whereas the elongation at break decreased. The strength property resulting from the thermoplastic component and the vulcanized NR was an essential component for improving the elasticity of the blends. These blends showed a greater elastic response than the neat ABS. The thermal stability of the blends increased with increasing ABS component. Scanning electron micrographs of the blends showed a two‐phase morphology system. The vulcanized 60 : 40 NR/ABS blend with 15‐phr phenolic resin showed a uniform styrene‐co‐acrylonitrile phase dispersed in the vulcanized NR phase; it provided better dispersion between the NR and ABS phases, and this resulted in superior elastic properties. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132, 42520.