全文获取类型
收费全文 | 367篇 |
免费 | 10篇 |
专业分类
电工技术 | 2篇 |
化学工业 | 135篇 |
金属工艺 | 24篇 |
机械仪表 | 5篇 |
建筑科学 | 2篇 |
矿业工程 | 1篇 |
能源动力 | 2篇 |
轻工业 | 19篇 |
石油天然气 | 28篇 |
无线电 | 41篇 |
一般工业技术 | 68篇 |
冶金工业 | 29篇 |
原子能技术 | 2篇 |
自动化技术 | 19篇 |
出版年
2023年 | 7篇 |
2022年 | 14篇 |
2021年 | 33篇 |
2020年 | 14篇 |
2019年 | 9篇 |
2018年 | 15篇 |
2017年 | 13篇 |
2016年 | 15篇 |
2015年 | 4篇 |
2014年 | 16篇 |
2013年 | 9篇 |
2012年 | 12篇 |
2011年 | 10篇 |
2010年 | 8篇 |
2009年 | 20篇 |
2008年 | 18篇 |
2007年 | 15篇 |
2006年 | 8篇 |
2005年 | 7篇 |
2004年 | 4篇 |
2003年 | 10篇 |
2002年 | 4篇 |
2001年 | 4篇 |
2000年 | 5篇 |
1999年 | 3篇 |
1998年 | 3篇 |
1997年 | 2篇 |
1996年 | 7篇 |
1994年 | 3篇 |
1993年 | 3篇 |
1992年 | 4篇 |
1991年 | 2篇 |
1990年 | 5篇 |
1989年 | 2篇 |
1986年 | 3篇 |
1985年 | 2篇 |
1984年 | 4篇 |
1983年 | 5篇 |
1981年 | 3篇 |
1979年 | 2篇 |
1978年 | 4篇 |
1977年 | 2篇 |
1976年 | 6篇 |
1975年 | 5篇 |
1974年 | 2篇 |
1973年 | 7篇 |
1971年 | 3篇 |
1970年 | 3篇 |
1969年 | 3篇 |
1968年 | 6篇 |
排序方式: 共有377条查询结果,搜索用时 16 毫秒
1.
EA Kalinina 《Canadian Metallurgical Quarterly》1993,(6):41-43
Major clinical characteristics of ovarian hyperstimulation syndrome are described and criteria of predicting the course of this disease and measures to prevent it presented. Statistical data on the presence of this syndrome in various forms during various schemes of superovulation stimulation are offered. Optimal schemes for the treatment of the condition are suggested. 相似文献
2.
Conclusions It has been found experimentally that to increase the uniformity of linear density of yarn spun from an aggressive spinning solution of 40–50 Pa·sec viscosity, it is necessary to use metering pumps of high output and to maintain a positive pressure difference of up to 1 MPa between the spinning solution pressure at intake and that at discharge from the pump.A new candle filter construction has been proposed for maintaining a positive difference between the spinning solution pressure at intake and at discharge.Translated from Khimicheskie Volokna, No. 1, pp. 40–41, January–February, 1986. 相似文献
3.
L. B. Pavlovich N. N. Nazarov V. P. Dolgopolov A. V. Kalinina T. A. Bulis D. V. Bal’tser V. P. Konstantinov 《Coke and Chemistry》2008,51(7):277-282
The use of biochemically purified water in place of industrial-grade water for the exhaust-gas scrubbers in the drying department of the coal-enrichment shop and for irrigation of the cyclone washers in the coke shops at OAO ZSMK is considered. It is found that biochemically purified water may be used for 100% of the water needs in coke production. Using biochemically purified water in the dust-trapping equipment, the coaland coke-dust content of the atmospheric emissions may be reduced by 24.5%. Additional purification of wastewater by adsorption on coke and coal dust is possible. 相似文献
4.
Olga V. Kovaleva Madina A. Rashidova Daria V. Samoilova Polina A. Podlesnaya Rasul M. Tabiev Valeria V. Mochalnikova Alexei Gratchev 《International journal of molecular sciences》2021,22(1)
There is an urgent need for identification of new prognostic markers and therapeutic targets for non-small cell lung cancer (NSCLC). In this study, we evaluated immune cells markers in 100 NSCLC specimens. Immunohistochemical analysis revealed no prognostic value for the markers studied, except CD163 and CD206. At the same time, macrophage markers iNOS and CHID1 were found to be expressed in tumor cells and associated with prognosis. We showed that high iNOS expression is a marker of favorable prognosis for squamous cell lung carcinoma (SCC), and NSCLC in general. Similarly, high CHID1 expression is a marker of good prognosis in adenocarcinoma and in NSCLC in general. Analysis of prognostic significance of a high CHID1/iNOS expression combination showed favorable prognosis with 20 months overall survival of patients from the low CHID1/iNOS expression group. For the first time, we demonstrated that CHID1 can be expressed by NSCLC cells and its high expression is a marker of good prognosis for adenocarcinoma and NSCLC in general. At the same time, high expression of iNOS in tumor cells is a marker of good prognosis in SCC. When used in combination, CHID1 and iNOS show a very good prognostic capacity for NSCLC. We suggest that in the case of lung cancer, tumor-associated macrophages are likely ineffective as a therapeutic target. At the same time, macrophage markers expressed by tumor cells may be considered as targets for anti-tumor therapy or, as in the case of CHID1, as potential anti-tumor agents. 相似文献
5.
Andreas Brodehl Alexey Meshkov Roman Myasnikov Anna Kiseleva Olga Kulikova Brbel Klauke Evgeniia Sotnikova Caroline Stanasiuk Mikhail Divashuk Greta Marie Pohl Maria Kudryavtseva Karin Klingel Brenda Gerull Anastasia Zharikova Jan Gummert Sergey Koretskiy Stephan Schubert Elena Mershina Anna Grtner Polina Pilus Kai Thorsten Laser Valentin Sinitsyn Sergey Boytsov Oxana Drapkina Hendrik Milting 《International journal of molecular sciences》2021,22(7)
About 50% of patients with arrhythmogenic cardiomyopathy (ACM) carry a pathogenic or likely pathogenic mutation in the desmosomal genes. However, there is a significant number of patients without positive familial anamnesis. Therefore, the molecular reasons for ACM in these patients are frequently unknown and a genetic contribution might be underestimated. Here, we used a next-generation sequencing (NGS) approach and in addition single nucleotide polymor-phism (SNP) arrays for the genetic analysis of two independent index patients without familial medical history. Of note, this genetic strategy revealed a homozygous splice site mutation (DSG2–c.378+1G>T) in the first patient and a nonsense mutation (DSG2–p.L772X) in combination with a large deletion in DSG2 in the second one. In conclusion, a recessive inheritance pattern is likely for both cases, which might contribute to the hidden medical history in both families. This is the first report about these novel loss-of-function mutations in DSG2 that have not been previously identi-fied. Therefore, we suggest performing deep genetic analyses using NGS in combination with SNP arrays also for ACM index patients without obvious familial medical history. In the future, this finding might has relevance for the genetic counseling of similar cases. 相似文献
6.
Sviatlana Kalinina Christian Freymueller Nilanjon Naskar Bjoern von Einem Kirsten Reess Ronald Sroka Angelika Rueck 《International journal of molecular sciences》2021,22(11)
Metabolic FLIM (fluorescence lifetime imaging) is used to image bioenergetic status in cells and tissue. Whereas an attribution of the fluorescence lifetime of coenzymes as an indicator for cell metabolism is mainly accepted, it is debated whether this is valid for the redox state of cells. In this regard, an innovative algorithm using the lifetime characteristics of nicotinamide adenine dinucleotide (phosphate) (NAD(P)H) and flavin adenine dinucleotide (FAD) to calculate the fluorescence lifetime induced redox ratio (FLIRR) has been reported so far. We extended the FLIRR approach and present new results, which includes FLIM data of the various enzymes, such as NAD(P)H, FAD, as well as flavin mononucleotide (FMN). Our algorithm uses a two-exponential fitting procedure for the NAD(P)H autofluorescence and a three-exponential fit of the flavin signal. By extending the FLIRR approach, we introduced FLIRR1 as protein-bound NAD(P)H related to protein-bound FAD, FLIRR2 as protein-bound NAD(P)H related to free (unbound) FAD and FLIRR3 as protein-bound NAD(P)H related to protein-bound FMN. We compared the significance of extended FLIRR to the metabolic index, defined as the ratio of protein-bound NAD(P)H to free NAD(P)H. The statistically significant difference for tumor and normal cells was found to be highest for FLIRR1. 相似文献
7.
Aleksandra A. Ageeva Ilya M. Magin Alexander B. Doktorov Victor F. Plyusnin Polina S. Kuznetsova Alexander A. Stepanov Alexander A. Alekseev Nikolay E. Polyakov Tatyana V. Leshina 《International journal of molecular sciences》2021,22(12)
The study of the L- and D-amino acid properties in proteins and peptides has attracted considerable attention in recent years, as the replacement of even one L-amino acid by its D-analogue due to aging of the body is resulted in a number of pathological conditions, including Alzheimer’s and Parkinson’s diseases. A recent trend is using short model systems to study the peculiarities of proteins with D-amino acids. In this report, the comparison of the excited states quenching of L- and D-tryptophan (Trp) in a model donor–acceptor dyad with (R)- and (S)-ketoprofen (KP-Trp) was carried out by photochemically induced dynamic nuclear polarization (CIDNP) and fluorescence spectroscopy. Quenching of the Trp excited states, which occurs via two mechanisms: prevailing resonance energy transfer (RET) and electron transfer (ET), indeed demonstrates some peculiarities for all three studied configurations of the dyad: (R,S)-, (S,R)-, and (S,S)-. Thus, the ET efficiency is identical for (S,R)- and (R,S)-enantiomers, while RET differs by 1.6 times. For (S,S)-, the CIDNP coefficient is almost an order of magnitude greater than for (R,S)- and (S,R)-. To understand the source of this difference, hyperpolarization of (S,S)-and (R,S)- has been calculated using theory involving the electron dipole–dipole interaction in the secular equation. 相似文献
8.
Irina A. Stenina Polina A. Yurova Tatyana S. Titova Marina A. Polovkova Oleg V. Korchagin Vera A. Bogdanovskaya Andrey B. Yaroslavtsev 《应用聚合物科学杂志》2021,138(27):50644
Nafion-117/PEDOT composite membranes were synthesized by in situ chemical polymerization of 3,4-ethylenedioxythiophene (EDOT) using ammonium persulfate as an oxidant. The polymerization of EDOT in Nafion membranes for various EDOT/oxidant treatment sequences was studied for the first time. PEDOT introduction leads to a slight decrease in both the ion-exchange capacity and water uptake of the composite membranes, as well as to an increase in cationic transport. Membranes initially treated with an oxidant exhibit better conductivity and lower hydrogen permeability. The effect of both modification of Nafion-117 membranes by PEDOT and hot-pressing of hydrogen-oxygen membrane-electrode assemblies (MEAs) on the performance of proton-exchange membrane fuel cells was studied. The maximum power density of the fabricated MEAs increases 1.5-fold: from 510 (for a pristine Nafion-117 membrane) to 810 mW cm−2 (for a membrane modified by PEDOT). The current density at a voltage of 0.4 V reaches 1248 and 2246 mA cm−2, respectively. 相似文献
9.
10.
V. B. Glushkova M. V. Kalinina P. A. Tikhonov N. S. Andreeva 《Glass Physics and Chemistry》2002,28(5):338-340
Complex cuprates of the compositions Bi1.6Pb0.4Sr1.8Ca2Cu3O
y
and Bi1.7Pb0.2Sb0.1Sr2Ca2Cu3O
y
are synthesized. The electrical properties of the superconductors prepared are investigated. Thin films based on the bismuth cuprates studied are produced. It is demonstrated that the thin films prepared can be used as electrodes being in contact with a solid electrolyte for designing oxygen partial pressure gauges. 相似文献