Synthesis and characterisation of copolyesters from poly(ethylene terephthalate) and poly(hexamethylene terephthalate)

Copolyesters containing poly(ethylene terephthalate) and poly(hexamethylene terephthalate) (PHT) were prepared by a melt condensation reaction. The copolymers were characterised by infrared spectroscopy and intrinsic viscosity measurements. The density of the copolyesters decreased with increasing percentage of PHT segments in the backbone. Glass transition temperatures (T_g). melting points (T_m) and crystallisation temperatures (T_c) were determined by differential scanning calorimetry. An increase in the percentage of PHT resulted in decrease in T_g, T_m and T_c. The as-prepared copolyesters were crystalline in nature and no exotherm indicative of cold crystallisation was observed. The relative thermal stability of the polymers was evaluated by dynamic thermogravimetry in a nitrogen atmosphere. An increase in percentage of PHT resulted in a decrease in initial decomposition temperature. The rate of crystallisation of the copolymers was studied by small angle light scattering. An increase in percentage of PHT resulted in an increase in the rate of crystallisation.     

Cumin Prevents 17β-Estradiol-Associated Breast Cancer in ACI Rats

Breast cancer (BC) is a leading cause of cancer deaths in women in less developed countries and the second leading cause of cancer death in women in the U.S. In this study, we report the inhibition of E2-mediated mammary tumorigenesis by Cuminum cyminum (cumin) administered via the diet as cumin powder, as well as dried ethanolic extract. Groups of female ACI rats were given either an AIN-93M diet or a diet supplemented with cumin powder (5% and 7.5%, w/w) or dried ethanolic cumin extract (1%, w/w), and then challenged with subcutaneous E2 silastic implants (1.2 cm; 9 mg). The first appearance of a palpable mammary tumor was significantly delayed by both the cumin powder and extract. At the end of the study, the tumor incidence was 96% in the control group, whereas only 55% and 45% animals had palpable tumors in the cumin powder and extract groups, respectively. Significant reductions in tumor volume (660 ± 122 vs. 138 ± 49 and 75 ± 46 mm³) and tumor multiplicity (4.21 ± 0.43 vs. 1.16 ± 0.26 and 0.9 ± 0.29 tumors/animal) were also observed by the cumin powder and cumin extract groups, respectively. The cumin powder diet intervention dose- and time-dependently offset E2-related pituitary growth, and reduced the levels of circulating prolactin and the levels of PCNA in the mammary tissues. Mechanistically, the cumin powder diet resulted in a significant reversal of E2-associated modulation in ERα, CYP1A1 and CYP1B1. Further, the cumin powder diet reversed the expression levels of miRNAs (miR-182, miR-375, miR-127 and miR-206) that were highly modulated by E2 treatment. We analyzed the composition of the extract by GC/MS and established cymene and cuminaldehyde as major components, and further detected no signs of gross or systemic toxicity. Thus, cumin bioactives can significantly delay and prevent E2-mediated mammary tumorigenesis in a safe and effective manner, and warrant continued efforts to develop these clinically translatable spice bioactives as chemopreventives and therapeutics against BC.     

Characterization of acidic groups in oxycelluloses III. Effect of cation freeing and blocking on estimation of carboxyl groups and lactones by the idometric method

A differentiation between free carboxyl and various lactone groups in different types of oxycelluloses was carried out based on the variation in their reaction rate with KI/KIO₃ solution. For oxycelluloses prepared under acidic conditions, a large proportion of carboxyl groups are present in free form. Each oxycellulose was also studied after cation freeing as well as after blocking the free carboxyl groups by treatment with sodium chloride. Cation freeing was found to cause considerable lactonization of carboxyl groups; sodium chloride treatment blocked them only partially.     

Electronic Contracts

As service-oriented computing increases, so does the role of e-contracts in helping business partners automate contractual agreements and relationships. The key challenge is to translate traditional contracts into executable e-contracts in a way that facilitates runtime monitoring and management. As research in this area progresses, organizations will have different approaches for modeling, implementing, and managing e-contracts. For now, developers must contend with several key research issues and challenges.     

Hydrodynamic behavior of inverse fluidized bed biofilm reactor for phenol biodegradation using Pseudomonas fluorescens

The hydrodynamic characteristic performance of an internal draft tube inverse fluidized bed biofilm reactor was studied for the aerobic biodegradation of phenol (1,200 mg/l) using Pseudomonas fluorescens for various ratios of settled bed volume to reactor working volume (V _b /V _r ) under batchwise condition with respect to liquid phase. The operating parameters, such as superficial gas velocity, phase hold ups, aspect ratio and bed height, were analyzed for different ratios of (V _b /V _r ). The effect of biodegradation on synthetic phenolic effluent was determined from the reduction in chemical oxygen demand and phenol removal efficiency. The optimum value of (V _b /V _r ) _m was 0.20 for the optimal superficial gas velocity, U _gm =0.220 m/s with the COD reduction efficiency of 98.5% in 48 hours. The biomass and biofilm characteristics of P. fluorescens were determined for optimal hydrodynamic operating parameters by evaluating its biofilm dry density and thickness, bioparticle density, suspended and attached biomass concentration.     

Design of a Compressive Sensing Based Fall detection System for Elderly Using WSN

Wireless Personal Communications - Recent researches have pointed out that one third persons are aged 65 and above requires special health care. As the number of elderly person is increasing, home...     

Dynamic connectivity and path formation time in Poisson networks

The connectivity of wireless networks is commonly analyzed using static geometric graphs. However, with half-duplex radios and due to interference, static or instantaneous connectivity cannot be achieved. It is not necessary, either, since packets take multiple time slots to propagate through the network. For example, if a packet traverses a link in one time slot, it is irrelevant if the next link is available in that time slot also, but it is relevant if the next hop exists in the next time slot. To account for half-duplex constraints and the dynamic changes in the transmitting set of nodes due to MAC scheduling and traffic loads, we introduce a random multi-digraph that captures the evolution of the network connectivity in a dynamic fashion. To obtain concrete results, we focus on Poisson networks, where transmitters form a Poisson point process on the plane at all time instants. We first provide analytical results for the degree distribution of the graph and derive the distributional properties of the end-to-end connection delay using techniques from first-passage percolation and epidemic processes. Next, we prove that under some assumptions, the delay scales linearly with the source–destination distance even in the presence of interference. We also provide simulation results in support of the theoretical results.     

Comparison of Conventional and Cross-Layer Multimedia Transport Schemes for Wireless Networks

Three competing schemes have been proposed for multimedia transport over broadband wireless channels: (a) traditional UDP (Postel, The User Datagram Protocol, 1980 [1]), (b) semi-cross-layer UDP-Lite (The Lightweight User Datagram Protocol, 2004 [2]), and (c) cross-layer header estimation (Khayam et al., IEEE Transactions on Multimedia 9(2):377–385, 2007 [3]; Khayam and Radha, IEEE Transactions on Wireless Communications 6(11):3946–3954, 2007 [4]). In all these schemes, corrupted and lost packets are recovered using FEC at the application layer. In this paper, we analytically and experimentally compare the performances of these broadband wireless multimedia schemes. First, we derive lower bounds on the excepted FEC redundancy required by ideal cross-layer header estimation, UDP and UDP-Lite over an arbitrary-order Markov wireless channel. We show that under realistic wireless channel conditions, the cross-layer header estimation scheme always requires lesser redundancy than UDP and UDP-Lite. We then propose a practical minimum distance decoding (MDD) header estimation scheme, which is receiver-based, low complexity and highly accurate. Trace-driven multimedia experiments over wireless LANs demonstrate that MDD header estimation requires significantly lesser FEC redundancy and renders better video quality than existing schemes.     

Header Detection to Improve Multimedia Quality Over Wireless Networks

Wireless multimedia studies have revealed that forward error correction (FEC) on corrupted packets yields better bandwidth utilization and lower delay than retransmissions. To facilitate FEC-based recovery, corrupted packets should not be dropped so that maximum number of packets is relayed to a wireless receiver's FEC decoder. Previous studies proposed to mitigate wireless packet drops by a partial checksum that ignored payload errors. Such schemes require modifications to both transmitters and receivers, and incur packet-losses due to header errors. In this paper, we introduce a receiver-based scheme which uses the history of active multimedia sessions to detect transmitted values of corrupted packet headers, thereby improving wireless multimedia throughput. Header detection is posed as the decision-theoretic problem of multihypothesis detection of known parameters in noise. Performance of the proposed scheme is evaluated using trace-driven video simulations on an 802.11b local area network. We show that header detection with application layer FEC provides significant throughput and video quality improvements over the conventional UDP/IP/802.11 protocol stack