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Do T. Hue Rebel Skirving Tong Chen John L. Williams Cynthia D.K. Bottema Kiro Petrovski 《Journal of dairy science》2021,104(7):8164-8176
Colostrum is essential for good neonate health; however, it is not known whether different calves absorb the nutrients from colostrum equally well. In this study, the absorption of protein, IgG, and γ-glutamyl transferase was compared in newborn dairy bull calves for 1 wk after feeding colostrum from different sources. Thirty-five Holstein-Friesian bull calves were randomly allocated into 3 groups and fed colostrum within 4 h after birth. Group A calves (n = 12) were bottle fed colostrum from their own dam for 3 d. Colostrum from these group A cows was also used as foster cow colostrum for the group B calves (n = 12), such that each group A and B calf pair received identical colostrum from each milking of the respective group A dam (10% of birth weight per day). The group C calves (n = 11) were fed 1 bottle (2 L) of pooled colostrum and transition milk (referred to as pooled colostrum), as was the standard practice on the dairy farm. The pooled colostrum was collected from the other dairy cows on the farm 0 to 4 d postpartum and stored at 4°C for less than 12 h. Blood was sampled from calves before the first feeding and at 1, 2, 3, and 7 d after birth. Levels of total solids, total protein, and IgG were higher in the dam colostrum than in the pooled colostrum. At birth, there were no differences between the calf groups for any measurements, and all calves had very low IgG levels. After receiving colostrum, the glucose, plasma γ-glutamyl transferase, serum total protein, and IgG concentrations increased significantly in all calves. There were no differences in any blood measurements at any time point between the pairs of group A and group B calves that received colostrum from the same cow except for the IgG concentration 2 d after birth. However, the group A calves had a higher total serum protein level and IgG concentration than the group C calves for all the time points after the first feeding. The group B calves had a higher IgG concentration than the group C calves on d 1, 2, and 7 after birth. Compared with groups A and B, there was no difference in the proportion of calves in group C that failed to have passive immunity transferred adequately based on the IgG threshold (<10 g/L). Thus, the calves receiving identical colostrum from the same cow had the same levels of IgG, and even the pooled colostrum provided sufficient transfer of IgG as the calves were fed within 4 h after birth. 相似文献
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C Lenz A Rebel K van Ackern W Kuschinsky KF Waschke 《Canadian Metallurgical Quarterly》1998,89(6):1480-1488
Antepartum plasma hepatitis C virus (HCV) RNA was quantified in 155 mothers coinfected with HCV and human immunodeficiency virus type 1 (HIV-1), and HCV RNA was serially assessed in their infants. Of 155 singleton infants born to HCV antibody-positive mothers, 13 (8.4%) were HCV infected. The risk of HCV infection was 3.2-fold greater in HIV-1-infected infants compared with HIV-1-uninfected infants (17.1% of 41 vs. 5.4% of 112, P = .04). The median concentration of plasma HCV RNA was higher among the 13 mothers with HCV-infected infants (2.0 x 10(6) copies/mL) than among the 142 mothers with HCV-negative infants (3.5 x 10(5) copies/mL; P < .001), and there were no instances of HCV transmission from 40 mothers with HCV RNA concentrations of < 10(5) copies/mL. Women dually infected with HIV-1 and HCV but with little or no detectable HCV RNA should be reassured that the risk of perinatal transmission of HCV is exceedingly low. 相似文献
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Embryonic hamster astroblasts (NN strain) grown in continuous line were cultivated in the presence of bromodeoxyuridine (BrdU).
A decrease in the growth rate of the cells and striking changes in their morphology were observed, the morphology of the cells
resembling that of mature astrocytes. Membrane lipids of BrdU-differentiated and standard cells were compared. No modification
of the lipid/protein ratio was observed. Phospholipids and cholesterol were increased in the same proprotions in the cells,
and no modification of the phospholipid distribution was observed. Ganglioside sialic acid remained at the same level, but
the ganglioside distribution was highly modified. Complex gangliosides appeared (GM1 and GD1a), while the proportion of simple gangliosides (GM3 and GD3) decreased. However, neither GT1 nor GQ1 were detected in differentiated cells. The distribution of phosphoglyceride acyl groups was highly modified, the proportion
of arachidonic and docosapentaenoic acids being 2 to 3 times higher in BrdU-treated cells than in proliferating ones. These
results were compared to those obtained with another clonal line of glial cells (C6) which exhibited no morphological differentiation
in the presence of BrdU; the lipids of these cells were not modified by such a treatment. 相似文献
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The lipid composition of plasma membranes isolated from bovine adrenal chromaffin cells has been determined. Choline and ethanolamine
phosphatides were predominant; the level of lyso compounds was very low. The amount of cholesterol and the cholesterol/phospholipid
molar ratio was low compared to those of the other subcellular fractions of chromaffin cells. A complex pattern of neutral
glycolipids was observed in contrast to that of gangliosides. 相似文献
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