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1.
Giulia Andreani Enea Ferlizza Riccardo Cabbri Micaela Fabbri Elisa Bellei Gloria Isani 《International journal of molecular sciences》2021,22(1)
The recent introduction of the Asian yellow-legged hornet, Vespa velutina, into Europe has raised concern regarding the threat to honeybees and the competition with the European hornet, Vespa crabro. The aim of this study was to investigated essential (Mg, Fe, Zn, Cu) and non-essential (Cd and Pb) elements in these two species. Element concentrations were determined in the whole body and separately in the head, thorax and abdomen using atomic absorption spectrometry (AAS). The changes in essential element concentration and speciation during metamorphosis were also studied using size exclusion chromatography followed by AAS and proteomic analysis. In both species, the essential elements were more concentrated in the abdomen due to the presence of fat bodies. Magnesium, Fe and Zn concentrations were significantly higher in V. crabro than in V. velutina and could have been related to the higher aerobic energy demand of the former species required to sustain foraging flight. Low concentrations of Cd and Pb were indicative of low environmental exposure. The concentration and speciation of essential elements, particularly Fe, varied among the developmental stages, indicating a modification of ligand preferences during metamorphosis. Overall, the results in the present study provide a better understanding of the hornet metal metabolism and a foundation for additional studies. 相似文献
2.
Virginia Veronica Visconti Ida Cariati Simona Fittipaldi Riccardo Iundusi Elena Gasbarra Umberto Tarantino Annalisa Botta 《International journal of molecular sciences》2021,22(8)
DNA methylation is one of the most studied epigenetic mechanisms that play a pivotal role in regulating gene expression. The epigenetic component is strongly involved in aging-bone diseases, such as osteoporosis and osteoarthritis. Both are complex multi-factorial late-onset disorders that represent a globally widespread health problem, highlighting a crucial point of investigations in many scientific studies. In recent years, new findings on the role of DNA methylation in the pathogenesis of aging-bone diseases have emerged. The aim of this systematic review is to update knowledge in the field of DNA methylation associated with osteoporosis and osteoarthritis, focusing on the specific tissues involved in both pathological conditions. 相似文献
3.
Ilaria Fraudentali Renato A. Rodrigues-Pousada Riccardo Angelini Sandip A. Ghuge Alessandra Cona 《International journal of molecular sciences》2021,22(10)
Polyamines are ubiquitous, low-molecular-weight aliphatic compounds, present in living organisms and essential for cell growth and differentiation. Copper amine oxidases (CuAOs) oxidize polyamines to aminoaldehydes releasing ammonium and hydrogen peroxide, which participates in the complex network of reactive oxygen species acting as signaling molecules involved in responses to biotic and abiotic stresses. CuAOs have been identified and characterized in different plant species, but the most extensive study on a CuAO gene family has been carried out in Arabidopsis thaliana. Growing attention has been devoted in the last years to the investigation of the CuAO expression pattern during development and in response to an array of stress and stress-related hormones, events in which recent studies have highlighted CuAOs to play a key role by modulation of a multilevel phenotypic plasticity expression. In this review, the attention will be focused on the involvement of different AtCuAOs in the IAA/JA/ABA signal transduction pathways which mediate stress-induced phenotypic plasticity events. 相似文献
4.
Simone Grassi Oscar Campuzano Mnica Coll Francesca Cazzato Georgia Sarquella-Brugada Riccardo Rossi Vincenzo Arena Josep Brugada Ramon Brugada Antonio Oliva 《International journal of molecular sciences》2021,22(8)
Inherited cardiomyopathies are frequent causes of sudden cardiac death (SCD), especially in young patients. Despite at the autopsy they usually have distinctive microscopic and/or macroscopic diagnostic features, their phenotypes may be mild or ambiguous, possibly leading to misdiagnoses or missed diagnoses. In this review, the main differential diagnoses of hypertrophic cardiomyopathy (e.g., athlete’s heart, idiopathic left ventricular hypertrophy), arrhythmogenic cardiomyopathy (e.g., adipositas cordis, myocarditis) and dilated cardiomyopathy (e.g., acquired forms of dilated cardiomyopathy, left ventricular noncompaction) are discussed. Moreover, the diagnostic issues in SCD victims affected by phenotype-negative hypertrophic cardiomyopathy and the relationship between myocardial bridging and hypertrophic cardiomyopathy are analyzed. Finally, the applications/limits of virtopsy and post-mortem genetic testing in this field are discussed, with particular attention to the issues related to the assessment of the significance of the genetic variants. 相似文献
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6.
Commercial poly(styrene-b-butadiene) copolymers (SBS) can act as effective compatibilizers in blends between high-impact polystyrene (HIPS) and polyethylene (PE), allowing a fine dispersion of PE in the polystyrene matrix, with a good balance of stiffness and impact strength. However, when processed under more severe conditions (e.g. in multiple extrusions, which simulate customer's product scrap recovery), the above blends show rather poor stability and their useful properties are rapidly lost. That undesirable effect is mainly due to cross-linking of SBS, which thus looses its compatibilizing activity. A correlation has been found between the time-to-cross-linking of SBS rubber in a Brabender mixer and the rapid decay of mechanical properties. The analysis of the mixing process and the morphology examinations of the final blend sample by TEM seem to support the above hypothesis. A significant reduction of block copolymer degradation has been achieved by means of a suitable stabilization. 相似文献
7.
Compatibilization of poly(2,6-dimethyl (PPE) with 1,4 phenylene-ether) PA6 has been achieved in two steps: first, (PPE) was functionalized with N-methyl-4-nitro-phthalimide; then, functionalized PPE was allowed to react, by melt blending, with the amine end group of PA6, giving a trans-imidation product. The reaction path was followed by torque measurements in a Brabender apparatus and the products characterized by infrared (i.r.) and nuclear magnetic resonance (NMR) spectroscopy. The above PPE/PA6 blends, modified with a suitable rubbery component (Kraton G), showed a remarkable Izod impact strength value, compared to the uncompatibilized mixture (170 versus 30 Jm–1). The maximum impact values were obtained with 1.65% functionalized PPE. 相似文献
8.
In this work, a possible way for partial CO2 emissions reduction from gas turbine exhausts by co-firing with biomass is investigated. The basic principle is the recirculation of a fraction of the exhausts (still rich in oxygen) to a gasifier, in order to produce syngas to mix with natural gas fuel. As biomass is a CO2 neutral fuel, the fraction of replaced natural gas is a measure of CO2 removal potential of the powerplant. 相似文献
9.
10.
D. Ghidoni G. C. Fasulo D. Cecchele M. Merlotti G. Sterzi R. Nocci 《Journal of Materials Science》1993,28(15):4119-4128
Polyblends of Nylon 6 and AES were prepared and their mechanical properties and phase morphology examined. Two compatibilization techniques were evaluated: addition of a suitable block copolymer: poly(styrene-co-maleic anhydride) (SMA); AES functionalization with maleic anhydride (MA) through reactive extrusion. As a preliminary test for the compatibilizing efficiency, SMAs and PA6 were compounded in a Brabender mixer, recording the torque during the operations and evaluating, by solvent extraction, the amount of SMA grafted to PA6. However, when moving to the ternary blends AES/SMA/PA6, the highest value of notched lzod impact strength (290 J m–1 versus 20 J m–1) was found for an SMA sample containing 24% MA, which did not show the highest reactivity with PA6 in the preliminary test run. This finding suggests that not only the reactivity towards PA6, but also the miscibility with AES phase (the highest for the SMA product with 24% MA) must be taken into account when designing the best performing compatibilizer. On the other hand, AES functionalization with MA and DCP proved to be more successful and the resulting 50/50 blend with PA6 exhibited an outstanding value of notched Izod impact strength (1050 J m–1) 相似文献