New ring-opening polymerization via a π-allylpalladium complex

Summary A binary system of a palladium complex as catalyst and zinc alkoxide as initiator conducted a novel ring-opening polymerization of cyclic carbonate, i. e., 5,5-dimethyl-4-ethenyl-1,3-dioxan-2-one. The polymerization proceeded along with releasing carbon dioxide to produce the corresponding polyether. The -allylpalladium complex generated from the monomer with the catalyst is the key intermediate for this new polymerization. The propagating end is zinc alkoxide, which nucleophilically attacks the monomer activated as the -allylpalladium complex in the propagation.     

数据库财务管理系统中的后台监督

本文借鉴某些大型机上的系统日记的思想,为自己的财务系统建立一个后台监督系统,以解决凭证数据库的数据修改问题以及由此引起的完整性和安全性问题。     

Electrical conductivity and domain structure in ferroelastic Tl2SeO4

We have carried out the optical observation, electrical conductivity and ²⁰⁵Tl NMR measurements, and subsequently investigated the origin of the large conductivity above ferroelastic phase transition temperature T_c (=661 K) on the basis of the domain structure and the crystal structure. Electrical conductivity exhibits the discontinuous increase around T_c with increasing temperature and becomes approximately 5 × 10⁻³ S m⁻¹ above T_c. Moreover, from the ²⁰⁵Tl NMR measurements, it is found that mobile Tl ions exist above T_c. Furthermore, from the analysis of the domain structure based on the crystal structure in the low-temperature ferroelastic phase, it is also found that the anomalously large fluctuations of SeO₄ tetrahedrons exist above T_c. It is deduced from these results that the high electrical conductivity above T_c is caused by the mobile Tl ions closely related to the anomalously large fluctuations of SeO₄ tetrahedrons accompanied by the ferroelastic phase transition.     

Mutated KIT Tyrosine Kinase as a Novel Molecular Target in Acute Myeloid Leukemia

KIT is a type-III receptor tyrosine kinase that contributes to cell signaling in various cells. Since KIT is activated by overexpression or mutation and plays an important role in the development of some cancers, such as gastrointestinal stromal tumors and mast cell disease, molecular therapies targeting KIT mutations are being developed. In acute myeloid leukemia (AML), genome profiling via next-generation sequencing has shown that several genes that are mutated in patients with AML impact patients’ prognosis. Moreover, it was suggested that precision-medicine-based treatment using genomic data will improve treatment outcomes for AML patients. This paper presents (1) previous studies regarding the role of KIT mutations in AML, (2) the data in AML with KIT mutations from the HM-SCREEN-Japan-01 study, a genome profiling study for patients newly diagnosed with AML who are unsuitable for the standard first-line treatment (unfit) or have relapsed/refractory AML, and (3) new therapies targeting KIT mutations, such as tyrosine kinase inhibitors and heat shock protein 90 inhibitors. In this era when genome profiling via next-generation sequencing is becoming more common, KIT mutations are attractive novel molecular targets in AML.     

Integrated reproduction of human motion components by motion copying system

Currently, the development of leading‐edge technology for recording and loading human motion on the basis of haptic information is required in the fields of manufacturing and human support. Human movement is an assembly of motion components. Since human movements should be supported by a robot in real time, it is necessary to integrate the motion components that were saved earlier. Once such motion integration is realized, future technology for use in daily human life can be developed. This paper proposes the integrated reproduction of the decomposed components of human motion by using a motion copying system. This system is the key technology for the realization of the acquisition, saving, and reproduction of real‐world haptic information. By using the proposed method, it is possible not only to achieve expert skill acquisition, skill transfer to robots, and power assist for each motion component, but also to open up new areas of applications. © 2012 Wiley Periodicals, Inc. Electr Eng Jpn, 181(1): 28–35, 2012; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/eej.21263     

An analysis of the length of hospital stay for cataract patients in Japan using the discrete-type proportional hazard model

We analyze the length of hospital stays of patients hospitalized for cataract and related diseases (Diagnosis Related Groups (DRG) 2041) in Japan, utilizing the data pertaining to 3436 patients on whom one-eye lens operations are performed. We use the discrete-type proportional hazard model to analyze variables that may affect the length of stay.     

广州新白云国际机场航站楼室外钢结构电焊缝涂装工艺

对于高空涂装的室外钢结构,不可能再对电焊缝部位进行电弧喷铝,而采用“锌加”单组分涂料是最好的选择,文章对涂装工艺作了简介,并论及了“锌加”的诸多优点。     

Control of Thermal Conductance of Peltier Device Using Heat Disturbance Observer

In industry, temperature control and heat flow control are now applied in many thermal devices, including Peltier devices, which facilitates heat transfer by the Peltier effect. Generally, temperature control compensates for heat flowing from the external environment, while heat actively flows into the system during heat flow control. Thus, temperature control and heat flow control differ from each other. However, there have been no detailed discussions of a thermal control process in which the thermal conductance control ranges between 0 and ∞. This paper focuses on thermal conductance control and the construction of a thermal conductance control system for a Peltier device using a heat disturbance observer. When using the thermal conductance controller, the thermal conductance control is altered and the system becomes thermally compliant with the external environment. This paper also presents experimental results that confirm the validity of the proposed control system. © 2013 Wiley Periodicals, Inc. Electr Eng Jpn, 185(4): 44–52, 2013; Published online in Wiley Online Library ( wileyonlinelibrary.com ). DOI 10.1002/eej.22411     

Numerical Modeling of an Earthquake-Induced Landslide Considering the Strain-Softening Characteristics at the Bedding Plane

The damage caused by an earthquake-induced landslide can generally be classified as either a limited deformation or a catastrophic failure. From an engineering point of view, the latter can be much more dangerous because the sliding mass may continue moving until it collides with another object. If a catastrophic failure occurs near a river, the debris may block the river, causing serious damage to the adjacent area. Therefore, examination of the mechanism of such catastrophic slope failures is important with respect to the mitigation of earthquake disasters in mountainous districts, although numerical modeling of such phenomena is rather difficult. In the present study, a new numerical model is developed to simulate an earthquake-induced catastrophic landslide that occured at a typical dip slope, namely, the Yokowatashi Landslide in Japan. In this case, the upper part of the bedrock on the planer tectonic dip surface slid more than 70 m. Only shear-strength degradation at the bedding plane could cause such a long-distance traveling failure. To investigate the strain-softening characteristics of the materials that filled the bedding plane, a series of laboratory tests involving undisturbed block samples was performed. The measured stress-displacement relationships under cyclic loading were numerically modeled as a newly proposed elasto-plastic constitutive model to be used in numerical simulations of landslide, based on the dynamic finite element method. The observed phenomena were appropriately simulated by the proposed method. The mechanism of catastrophic failure is discussed in detail in this paper in order to clarify the relationships between the strain-softening characteristics and the global slope stability. Our newly proposed method to evaluate the possibility of a catastrophic failure was applied to the landslide, and the moment when the slope becomes unstable was able to be predicted. The results confirm that the proposed method can predict the catastrophic failure of a slope.     

Chemical modification of zein by bifunctional polycaprolactone (PCL)

Prepolymer was synthesized by use of PCL and hexamethylene diisocyanate (HDI), and then used to prepare modified zein-based polymers (ZPs). Solid-state ¹³C NMR results showed that at least four amino acids (Glu, Gln, Tyr and His) reacted with the prepolymer, and urea-urethane links were prominent. Thermal analysis indicated that micro-phase separation formed between zein matrix and PCL-HDI (PCLH) component in ZPs. With the increasing PCLH content, the melting point of PCL in ZP decreased, and the T_g of zein reduced due to plasticizer role of PCLH. The breaking elongation of modified zein containing 10% PCLH content, increased about 15 times while its strength at break only reduced by about 2 times than that of commercial zein. In addition, with the increasing PCLH content, the flexibility of modified zein sheet improved dramatically with negligible reduction in strength. This indicates that PCL was an elastic fraction in ZPs. Therefore, it is an effective way to improve the mechanical properties of zein by modification with PCL, showing a potential in the field of biodegradable polymers.