Design and performance study of phase‐locked loop using fractional‐order loop filter

The present work reports the realization of an analog fractional‐order phase‐locked loop (FPLL) using a fractional capacitor. The expressions for bandwidth, capture range, and lock range of the FPLL have been derived analytically and then compared with the experimental observations using LM565 IC. It has been observed that bandwidth and capture range can be extended by using FPLL. It has also been found that FPLL can provide faster response and lower phase error at the time of switching compared to its integer‐order counterpart. Copyright © 2014 John Wiley & Sons, Ltd.     

A review on the synthesis of in situ aluminum based composites by thermal,mechanical and mechanical–thermal activation of chemical reactions

The aim of the present paper is to review the recent progress in the synthesis of in situ particle reinforced aluminum composites using thermal, mechanical and combined mechanical-thermal activation of aluminothermic reduction reactions. The combination of combustion synthesis (CS) and mechanosynthesis (MS) is the most recent development in the processing of advanced materials like micro and nano aluminum based composites. The combined mechanical thermal synthesis (MTS) has widened the possibilities for both CS and MS. MTS holds great potential for commercial viability and offers exciting processing route for the synthesis of advanced materials. Enhanced reaction kinetics and extended concentration limits in MTS are demonstrated by illustrating the synthesis of aluminum based nanocomposite involving Al–CeO₂.     

The Radical Versus Non-radical Reactive Intermediates in the Iron(III) Porphyrin Catalyzed Oxidation Reactions by Hydroperoxides, Hydrogen Peroxide and Iodosylarene

In the catalytic reaction of an iron(III) porphyrin with t-BuOOH, CumOOH, H₂O₂ and C₆F₅IO, cyclohexene was used as a probe substrate. The selective hydroxylation of cyclohexene by hydroperoxides proceeds through radical path and this has been utilized for successful dioxygen activation/autooxidation. For other oxidants epoxide was the major product and the reactions proceed through non-radical path.     

Mössbauer Study of the Influence of Fe-Si-N Liquid in the Synthesis of β-Si3N4 from Silica

Mössbauer spectra of the products obtained by carbothermal reduction and distribution of silica in the presence of iron in the temperatures range 1200^o to 1540^o were studied. The preponderance of β- Si₃N₄ over the α form at a higher reaction temperature were assumed to be related to the formation of an Fe-Si-N liquid. The liquid did not alter its composition with the variation of reduction-temprature, Iron had no effect on the reaction mechanism below 1300^oC.     

Favorable influence of ssDNA-functionalized SWCNT on the navigation pattern of C. elegans

Microsystem Technologies - Single-Walled Carbon Nanotubes (SWCNTs) are widely used as potential carriers in drug delivery systems. The objective of this work was to observe the effects of pristine,...     

Modulation of Tubular pH by Acetazolamide in a Ca2+ Transport Deficient Mice Facilitates Calcium Nephrolithiasis

Proximal tubular (PT) acidosis, which alkalinizes the urinary filtrate, together with Ca²⁺ supersaturation in PT can induce luminal calcium phosphate (CaP) crystal formation. While such CaP crystals are known to act as a nidus for CaP/calcium oxalate (CaOx) mixed stone formation, the regulation of PT luminal Ca²⁺ concentration ([Ca²⁺]) under elevated pH and/or high [Ca²⁺] conditions are unknown. Since we found that transient receptor potential canonical 3 (TRPC3) knockout (KO; -/-) mice could produce mild hypercalciuria with CaP urine crystals, we alkalinized the tubular pH in TRPC3-/- mice by oral acetazolamide (0.08%) to develop mixed urinary crystals akin to clinical signs of calcium nephrolithiasis (CaNL). Our ratiometric (λ340/380) intracellular [Ca²⁺] measurements reveal that such alkalization not only upsurges Ca²⁺ influx into PT cells, but the mode of Ca²⁺ entry switches from receptor-operated to store-operated pathway. Electrophysiological experiments show enhanced bicarbonate related current activity in treated PT cells which may determine the stone-forming phenotypes (CaP or CaP/CaOx). Moreover, such alkalization promotes reactive oxygen species generation, and upregulation of calcification, inflammation, fibrosis, and apoptosis in PT cells, which were exacerbated in absence of TRPC3. Altogether, the pH-induced alteration of the Ca²⁺ signaling signature in PT cells from TRPC3 ablated mice exacerbated the pathophysiology of mixed urinary stone formation, which may aid in uncovering the downstream mechanism of CaNL.