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1.
The response of turbulent pipe flow to sudden changes in wall roughness and flow cross-sectional area has been studied experimentally and numerically. Changes typical of those encountered by the gas phase in annular gas-liquid flow have been considered. The results show that the flow field and the pressure field can be significantly distorted at these transitions. Good agreement has been obtained between the measured results and those calculated using the Harwell-FLOW3D computational fluid dynamics (CFD) code. 相似文献
2.
Suresh C. Tyagi Sathnur Pushpakumar Utpal Sen Sri Prakash L. Mokshagundam Dinesh K. Kalra Mohamed A. Saad Mahavir Singh 《International journal of molecular sciences》2023,24(1)
Although progressive wasting and weakness of respiratory muscles are the prominent hallmarks of Duchenne muscular dystrophy (DMD) and long-COVID (also referred as the post-acute sequelae of COVID-19 syndrome); however, the underlying mechanism(s) leading to respiratory failure in both conditions remain unclear. We put together the latest relevant literature to further understand the plausible mechanism(s) behind diaphragm malfunctioning in COVID-19 and DMD conditions. Previously, we have shown the role of matrix metalloproteinase-9 (MMP9) in skeletal muscle fibrosis via a substantial increase in the levels of tumor necrosis factor-α (TNF-α) employing a DMD mouse model that was crossed-bred with MMP9-knockout (MMP9-KO or MMP9-/-) strain. Interestingly, recent observations from clinical studies show a robust increase in neopterin (NPT) levels during COVID-19 which is often observed in patients having DMD. What seems to be common in both (DMD and COVID-19) is the involvement of neopterin (NPT). We know that NPT is generated by activated white blood cells (WBCs) especially the M1 macrophages in response to inducible nitric oxide synthase (iNOS), tetrahydrobiopterin (BH4), and tetrahydrofolate (FH4) pathways, i.e., folate one-carbon metabolism (FOCM) in conjunction with epigenetics underpinning as an immune surveillance protection. Studies from our laboratory, and others researching DMD and the genetically engineered humanized (hACE2) mice that were administered with the spike protein (SP) of SARS-CoV-2 revealed an increase in the levels of NPT, TNF-α, HDAC, IL-1β, CD147, and MMP9 in the lung tissue of the animals that were subsequently accompanied by fibrosis of the diaphragm depicting a decreased oscillation phenotype. Therefore, it is of interest to understand how regulatory processes such as epigenetics involvement affect DNMT, HDAC, MTHFS, and iNOS that help generate NPT in the long-COVID patients. 相似文献
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K. Sri Bala Kameswari Chitra Kalyanaraman S. Porselvam K. Thanasekaran 《Clean Technologies and Environmental Policy》2012,14(2):241-250
The inoculum to substrate (I/S) ratio is an important factor which influences the anaerobic digestion process. In this study, the effect of different I/S ratios on the performance of co-digestion of fleshings along with mixture of sludge generated during treatment of tannery
wastewater was investigated. The parameters studied were biogas generation, volatile solids reduction, volatile fatty acid
(VFA) production, and the stability of the digestion process based on VFA to alkalinity ratio was evaluated for various I/S ratios. Economical significance of I/S ratio as related to the volume of the anaerobic digester and the potential benefit of bio-energy generated are discussed
in detail. 相似文献
6.
Effect of ozonation and ultrasonication pretreatment processes on co-digestion of tannery solid wastes 总被引:1,自引:1,他引:0
K. Sri Bala Kameswari Chitra Kalyanaraman K. Thanasekaran 《Clean Technologies and Environmental Policy》2011,13(3):517-525
Studies were carried out by the application of ozonation and ultrasonication as pretreatment processes on primary and secondary
sludge generated during treatment of tannery wastewater to enhance the soluble chemical oxygen demand (SCOD). Further, co-digestion
(simultaneous digestion of two or more substrates) studies were carried out in batch reactors using the fleshings (a solid
waste generated during the processing of raw hides or skins into finished leather) along with the primary and the secondary
sludge wherein biogas generation was compared with and without pre-treated sludge using ozone and ultrasonication processes,
respectively. It was found that, application of pretreatment processes enhanced biogas generation by 45% in the case of ozone
pre-treated sludge and 53% by ultrasonication processes, respectively, in conjunction with the fleshings. However, considering
the optimum contact time required, application of ultrasonication as a pretreatment process was found to be the most appropriate
and viable process to enhance the SCOD. This pretreatment process has the potential for implementation in tanneries using
the shortest possible ultrasonication time to minimize energy cost when compared with ozonation time. 相似文献
7.
Pamidighantam Prabhakara Rao Galla Narsing Rao Tummala Jyothirmayi Akula Satyanarayana Mallampalli Sri Lakshmi Karuna Rachapudi Badari Narayana Prasad 《Journal of the American Oil Chemists' Society》2015,92(10):1483-1490
Bixa orellana L. seeds possess a resinous lipid (6.3 %), which has a pungent and spicy odour. The seed is known for its medicinal properties such as anti‐inflammatory, antipyretic activity and as a cure for tonsilitis. Trachyspermum copticum L. seed is a well known digestive aid and relief from colic pain. T. copticum possesses essential oil rich in thymol (>50 %) and lipid (15.6 %). The present study was aimed to quantify lipid classes of these two species by silicic acid chromatography and analyze their fatty acid composition by gas chromatography (GC) and gas chromatography–mass spectrometry (GC–MS). It was observed that the seed lipids are rich in neutral lipids with 98.1 and 95.2 % and lower quantities of glycolipids of 1.5 and 3.8 % and phospholipids of 0.36 and 1.0 % in B. orellana and T. copticum, respectively. The fatty acid composition of B. orellana seed lipid showed major quantities of palmitic (26.9 %), linoleic (26.1 %), oleic (17.5 %), linolenic (15.1 %), stearic acid (10.8 %) and small quantities of eicosanoic acid (3.6 %). In T. copticum seed lipids, petroselinic acid (68.3 %) and linoleic acid (25.3 %) together constituted 93 % of the total lipid. The results revealed that the lipids after recovery of the essential components namely, bixin and volatile oil from B. orellana and T. copticum, respectively can be further explored for industrial applications. 相似文献
8.
Ilham Alimuddin Luhur Bayuaji Rohaya Langkoke Josaphat Tetuko Sri Sumantyo Hiroaki Kuze 《土木工程与建筑:英文版》2013,(10):1287-1294
Urban growth has been a major issue in environmental monitoring and changes occurred on land surfaces have been monitored by applying remote sensing as well as ground measurement. Most major cities in the world have experienced land subsidence phenomena on some parts of them due to the load of development and modernization. Excessive extraction of groundwater for the needs of industry has led to the condition where the water table drops, and this can possibly trigger subsidence, as observed in Indonesian cities. In this study the authors have shown that the application of DInSAR (differential interferometric synthetic aperture radar) technique using Japanese Earth Resources Satellite-I Synthetic Aperture Radar JERS-I SAR data can reveal subsidence conditions in the studied Makassar city area. Landsat TM (thematic mapper) images were used to evaluate the change of land cover during the observation period of 1994-1999. Makassar is fiat, covered mainly by alluvium deposit that is vulnerable to the load of constructions, and volcanic formations which is porous and will easily be degraded by groundwater extraction. It is found that mostly the subsidence has occurred in the western part of the city, including the industrial district, reclamation area, trading center area and the seaport area. The ground survey has indicated that high human activity exists in every point of subsidence. It is likely that various human activities such as ground water pumping and construction work should have affected the local subsidence phenomena in Makassar, as in the case of other large-scale cities in Indonesia. 相似文献
9.
Gobinath V. K. Rajasekar R. Santhosh S. Moganapriya C. Sri A. Manju Jaganathan S. K. 《SILICON》2022,14(15):9773-9788
Silicon - Antireflection coatings (ARCs) have become one of the key techniques for mass production of Si solar cells. They are generally performed by vacuum processes such as thermal evaporation,... 相似文献
10.
The asymptotic behavior of coupled nonlinear dynamical systems in the presence of noise is studied using the method of stochastic averaging. It is shown that, for systems with rapidly oscillating and decaying components, the stochastic averaging technique yields a set of equations of considerably smaller dimension, and the resulting equations are simpler. General results of this method are applied to stochastically perturbed nonlinear nonconservative systems in R4. It is shown that in such systems the contribution of the stochastic components in the damped modes to the drift term of the critical mode may be beneficial in terms of stability in certain cases. 相似文献