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排序方式: 共有191条查询结果,搜索用时 15 毫秒
1.
B Ljunggren 《Canadian Metallurgical Quarterly》1993,78(1):142-149
Herbert Olivecrona (1891-1980) singlehandedly founded Swedish neurosurgery. At the International Congress in Neurology in Bern in August, 1931, Harvey Cushing invited the cream of the world's medical society to a private banquet. Among the 28 specially invited guests was Herbert Olivecrona. At 40 years old, Olivecrona took his seat with pioneers such as Otfrid Foerster, Percival Bailey, Hugh Cairns, Geoffrey Jefferson, and Sir Charles Sherrington. This suggests that Cushing was impressed by the Swedish aristocrat's didactic deeds when he visited the Serafimer Hospital in Stockholm 2 years earlier. During the mid-1920's, the radiologist Erik Lysholm greatly improved the technique of ventriculography and, challenged by Olivecrona, his diagnostic neuroradiology became of superior quality. In the early 1930's, utilizing technical innovations of his own, Lysholm became a master at demonstrating and localizing posterior fossa tumors, which Olivecrona then operated on. Olivecrona's clinic became the mecca to which many scholars, thirsting for more knowledge, went on a pilgrimage. The international reputation of the clinic was founded, not on epoch-making discoveries, but by the resolute and practical application of methods already launched elsewhere and the exemplary organization that Olivecrona had established in collaboration with Lysholm. In spite of hardships and primitive working conditions, the clinic at the Serafimer Hospital gradually developed into the ideal prototype for a modern neurosurgical department. Olivecrona trained many colorful personalities who later were to lay the foundation for neurosurgery in their home countries; these included Wilhelm T?nnis of Germany, Edvard Busch of Denmark, and Aarno Snellman of Finland. Olivecrona was a true pioneer who made major contributions in practically all fields of conventional neurosurgery. 相似文献
2.
E Persson M Ljunggren J la Cour Jansen R Strube L J?nsson 《Water science and technology》2006,53(12):139-147
A Discfilter with 10 and 18 microm filter openings, respectively, was placed in parallel to a flotation plant for separation of biological flocs from a post-denitrifying Kaldnes Moving Bed Process, the last treatment step at the municipal wastewater treatment plant at Sj?unda, Malm?, Sweden. The effluent concentrations from the 10 and 18 microm filter were 2-5 and 2-8 mg SS L(-1), respectively, which is comparable to, or better than, the flotation plant. Comparison with experiences from activated sludge plants shows that the Discfilter works especially well after the Kaldnes process. Particle size distribution (PSD) studies show that particles larger than the filter openings of 10 and 18 microm are separated with approximately 90% efficiency, whereas most of the smaller particles pass the filter. This fact indicates that the major particle separation mechanism is physical blocking. These findings point to the possibility of improving the prediction of the separation efficiency by combining measurements of turbidity and suspended solids with particle size analysis. 相似文献
3.
4.
Sten Kaiser 《International Journal of Fracture》1985,29(2):85-99
The stability of a cracked, nonlinear component connected to an elastic structure and subjected to an arbitrary number of
controlled loads or displacements, is discussed. First this is done with a general instability criterion expressed in terms
of loads and displacements of the cracked part. Then general expressions for the tearing modulus are given for different loading
situations. Finally the given equations are applied to SEN specimens under bending and tension.
Résumé On discute de la stabilité d'un composant fissuré et non linéaire assemblé à une structure élastique et soumis à un monbre quelconque de charges ou de déplacements, appliqués dans des conditions connues. Ceci est réalisé en faisant appel, en premier lieu, à un critère général d'instabilité exprimé en termes the sollicitation et de déplacement de la portion fissurée. Ensuite, on fournit des expressions générales pour le module d'arrachement, correspondant à diverses situations de mise en charge. Enfin, les équations obtenues sont appliquées à des éprouvettes à entaille latérale simple soumises à flexion et traction.相似文献
5.
Katarzyna Jasieniecka-Gazarkiewicz Kamil Demski Satinder K. Gidda Sylwia Kliska Janusz Niedojado Ida Lager Anders S. Carlsson Elena A. Minina Robert T. Mullen Peter V. Bozhkov Sten Stymne Antoni Bana 《International journal of molecular sciences》2021,22(6)
Arabidopsis thaliana possesses two acyl-CoA:lysophosphatidylethanolamine acyltransferases, LPEAT1 and LPEAT2, which are encoded by At1g80950 and At2g45670 genes, respectively. Both single lpeat2 mutant and double lpeat1 lpeat2 mutant plants exhibit a variety of conspicuous phenotypes, including dwarfed growth. Confocal microscopic analysis of tobacco suspension-cultured cells transiently transformed with green fluorescent protein-tagged versions of LPEAT1 or LPEAT2 revealed that LPEAT1 is localized to the endoplasmic reticulum (ER), whereas LPEAT2 is localized to both Golgi and late endosomes. Considering that the primary product of the reaction catalyzed by LPEATs is phosphatidylethanolamine, which is known to be covalently conjugated with autophagy-related protein ATG8 during a key step of the formation of autophagosomes, we investigated the requirements for LPEATs to engage in autophagic activity in Arabidopsis. Knocking out of either or both LPEAT genes led to enhanced accumulation of the autophagic adaptor protein NBR1 and decreased levels of both ATG8a mRNA and total ATG8 protein. Moreover, we detected significantly fewer membrane objects in the vacuoles of lpeat1 lpeat2 double mutant mesophyll cells than in vacuoles of control plants. However, contrary to what has been reported on autophagy deficient plants, the lpeat mutants displayed a prolonged life span compared to wild type, including delayed senescence. 相似文献
6.
Microsomes of developing soya bean cotyledons transfer oleate from oleoyl-CoA to phosphatidylcholine (PC) by two different
mechanisms: one in which oleate transfer is accompanied by the release of free CoA and another which results in the exchange
of oleate from oleoyl-CoA for unsaturated 18-carbon fatty acids of PC. The acyl exchange can be demonstrated only when bovine
serum albumin is present in the incubation medium. ATP-dependent acyl-CoA synthetase is not involved in the exchange process,
which apparently does not require any cofactors. In light of this exchange process, the oleate desaturase system was reinvestigated
in order to determine what the actual substrate for this system is. Upon incubation of microsomes with high concentrations
of [14C] oleoyl-CoA, bovine serum albumin and NADH, it could be conclusively demonstrated that most oleic acid is desaturated while
part of the PC molecule. The amounts of [14C] linoleoyl-CoA formed could be explained entirely by the acyl exchange. The physiological significance of the acyl exchange
system is discussed. A new method for separation of acyl-CoA from other lipids and free CoA using reversed phase column chromatography
also is described. 相似文献
7.
Maureen Bafor Allan Keith Stobart Sten Stymne 《Journal of the American Oil Chemists' Society》1990,67(4):217-225
Microsomal membrane preparations from the developing seeds of safflower (Carthamus tinctorius, var. Gila) and turnip-rape (Brassica campestris, var. Bele) catalyzed the assembly of triacylglycerols (triglycerides) from sn-glycerol 3-phosphate and acyl-CoA. The membrane
preparations were used to assess the acyl specificity properties of the initial acylating enzymes—glycerol 3-phosphate acyltransferase
(GPAT) and 1-acylglycerol 3-phosphate acyltransferase (lysophosphatidic acid acyltransferase, LPAAT)—that are responsible
for the fatty acids at positions sn-1 and sn-2 of the sn-triacylglycerol, respectively. In spectrophotometric assays it was
possible to evaluate, to some extent, how these enzymes will utilize unusual and foreign fatty acids that are not normally
found in these particular plant species. The acylating enzymes from both plants used, to varying extents, a comprehensive
range of acyl-CoA donor species and some kinetic properties of the substrates involved are presented. The enzymes from safflower,
however, were generally the more selective, whereas the turnip-rape was less particular and could utilize a range of acyl
substrates. The enzymes from both plants hardly utilized erucate (C22∶1), and the significance of this is discussed in terms
of mechanisms which have evolved in order to exclude certain, perhaps detrimental, fatty acids from structural membrane lipids
and dedicate them to storage lipid assembly.
The ability of the microsomal preparations, from the developing seeds of both plants, to synthesize cocoabutter type fats
was investigated. Microsomal membranes were incubated with glycerol 3-phosphate and equimolar amounts of palmitate, oleate
and stearate. Safflower preparations catalyzed the construction of sn-triacylglycerol with largely palmitate, oleate and stearate
in positions sn-1, 2 and 3, respectively. The selectivity for acyl species in rape was less pronounced, however, substantial
saturated-unsaturated-saturated oils were still produced. The results are discussed in terms of the acyl selectivity properties
of the glycerol acylating enzymes. It is evident that given the correct composition of fatty acids, the plant can produce
cocoabutter or other exotic fats. 相似文献
8.
Björn Sten Mark Kretzschmar Paul Bergelt Daniel Göhler Fabian Firmbach Ronny Köcher Andreas Heft 《Aerosol science and technology》2020,54(10):1124-1134
Abstract For the purpose of silica surface layer modulation, a pneumatic-controlled two-substance atomizer with inertia-based coarse droplet separation was operated at different system pressures for tetraethyl orthosilicate precursor aerosol supply during combustion chemical vapor deposition. A comprehensive testing study was performed to characterize the atomizer’s performance characteristics, initial precursor aerosols at the atomizer’s outlet, transformed aerosols before combustion, combustion aerosols and formed layers. Laser diffraction spectrometry, differential electrical mobility analyses and condensation particle counting were used for aerosol characterization with regard to particle size and particle production quantities. Layers were characterized by scanning electron microscopy, atomic force microscopy, spectral ellipsometry, water contact angle measurements and light transmission concerning geometric properties (thickness, surface structure and roughness) and physical behaviors (i.e., optical behaviors, hydrophobicity). Results show a quasi-linear relationship of the ejection mass flow of the pneumatic-controlled atomizer and geometric layer properties which again show a direct relationship to the physical properties. No correlation was found between the aerosols before combustion and the combustion aerosols since the majority of combustion aerosol particles are synthesized solely from the gas phase based on evaporated precursor material. Copyright © 2020 American Association for Aerosol Research 相似文献
9.
10.
Bernt M. kesson John Bagterp Jrgensen Niels Kjlstad Poulsen Sten Bay Jrgensen 《Journal of Process Control》2008,18(7-8):769-779
This paper discusses a method for estimating noise covariances from process data. In linear stochastic state-space representations the true noise covariances are generally unknown in practical applications. Using estimated covariances a Kalman filter can be tuned in order to increase the accuracy of the state estimates. There is a linear relationship between covariances and autocovariance. Therefore, the covariance estimation problem can be stated as a least-squares problem, which can be solved as a symmetric semidefinite least-squares problem. This problem is convex and can be solved efficiently by interior-point methods. A numerical algorithm for solving the symmetric is able to handle systems with mutually correlated process noise and measurement noise. 相似文献