Inhibiting effects of serotonin and serotonin antagonists on the migration of mononuclear leucocytes

The effect of serotonin and the serotonin antagonists ketanserin, methiotepine and ICS-205-930 on the migration of leucocytes was studied by using the sealed capillary migration technique. The migration of mononuclear leucocytes was inhibited by serotonin at 10(-4) and 10(-6)-10(-10)mol/l. An inhibition of the mononuclear leucocyte migration was also caused by ICS-205-930 at 10(-4)mol/l, ketanserin at 10(-4) and 10(-8)-10(-10)mol/l and methiotepine at 10(-4) and 10(-6)-10(-8)mol/l. No inhibiting effects of serotonin or the serotonin antagonists were found on the migration of polymorphonuclear leucocytes. Thus, both serotonin and serotonin antagonists may inhibit mononuclear leucocyte migration.     

Condition based replacement policies—a counting process approach

This paper presents a general framework for analysing condition based replacement policies for stochastically failing units. The framework is based on the theory of counting processes. A replacement policy minimizing the long run expected cost is determined. The paper discusses both non-repairable and repairable units. Two examples are analysed in detail: shock models and monotone (coherent) systems.     

The use of non-proven therapy among patients treated in Norwegian oncological departments. A cross-sectional national multicentre study

A national multicentre study was performed to investigate the prevalent use of "alternative medicine", here called "non-proven therapies (NPT)", applied among Norwegian cancer patients. Of 911 patients invited to take part in the study, 642 were included in the analysis. Demographic characteristics were collected for all patients. The participating physicians gave information about the patients' clinical characteristics. Among 630 evaluable patients, 20% had been or were present users of NPTs for their oncological disease. The preferred methods were healing by hand and faith healing. Herbs, vitamins, diets and Iscador were other popular methods. As many as 40% of the users of NPTs had used NPTs earlier for non-malignant diseases. Elderly patients were less likely to use NPTs. Use was high in the northern part of Norway.     

Policy-based Awareness Management (PAM): Case study of a wireless communication system at a hospital

The present paper evaluates the use of software agents to identify relevance of information, called awareness. This evaluation is based on existing policies and scenarios in the context of wireless communication of a hospital in Norway. The study is to address the lack of literature for experimental studies on a method to employ software agents for awareness identification. Research in computer supported cooperative work indicates the significant contributions of software agents to assist individuals. There are bodies of work that show awareness provides the means for software agents in which effective cooperation can take place. In addition, the role of the methods to identify awareness is emphasized in the literature of both computer supported cooperative work and software agents. This paper explains a step-wise process, called Policy-based Awareness Management, which allows agents to use policies as a source to identify awareness and thus change their behaviors accordingly. The contribution of this method is based on the concepts proposed by the logic of general awareness. The present study applies Directory Enabled Networks-next generation as the policy structure for the method. The paper evaluates the process via its application to identify the relevance of information in wireless communication scenarios in a hospital. The present study conducts observations, interviews and discussions on the wireless communication system of the hospital to identify the different scenarios happening in the system. The paper presents a set of simulations on these scenarios and concludes that the method is effective and cost-efficient.     

High temperature Seebeck coefficient and resistance measurement system for thermoelectric materials in the thin disk geometry

A versatile apparatus to measure the cross-plane Seebeck coefficient and the resistivity of bulk samples shaped as disks or thin plates, over a temperature range of 300 K-620 K with possible extension to higher temperatures, is presented. It is constructed from readily available equipment and instrumentation with parts that are easily manufactured. The Seebeck coefficient is measured over an average region of the sample under steady-state conditions. The sample resistance is measured using a four-point alternating current method and scaled to room temperature measurements with known geometry to calculate resistivity. A variety of sample shapes are supported. Most importantly, the support of the thin disk geometry allows for the very same samples to be used in a laser flash instrument. The design allows for rough vacuum, high vacuum, or purging with inert gases in the sample chamber. Measurements on thermoelectric ZnSb and a Ni reference material are presented.     

Maintaining awareness using policies; Enabling agents to identify relevance of information

The field of computer supported cooperative work aims at providing information technology models, methods, and tools that assist individuals to cooperate. The presented paper is based on three main observations from literature. First, one of the problems in utilizing information technology for cooperation is to identify the relevance of information, called awareness. Second, research in computer supported cooperative work proposes the use of agent technologies to aid individuals to maintain their awareness. Third, literature lacks the formalized methods on how software agents can identify awareness. This paper addresses the problem of awareness identification. The main contribution of this paper is to propose and evaluate a formalized structure, called Policy-based Awareness Management (PAM). PAM extends the logic of general awareness in order to identify relevance of information. PAM formalizes existing policies into Directory Enabled Networks-next generation structure and uses them as a source for awareness identification. The formalism is demonstrated by applying PAM to the space shuttle Columbia disaster occurred in 2003. The paper also argues that efficacy and cost-efficiency of the logic of general awareness will be increased by PAM. This is evaluated by simulation of hypothetical scenarios as well as a case study.     

Glazed spaces in Nordic climates

A semi-climatized zone in the shape of a glazed space is heated to some degree by solar radiation and to some degree by excess heat or heat loss from the main and fully insulated part of the building. Such a space will not offer full thermal comfort for permanent occupancy during the winter season, but it is useful for secondary functions such as circulation, storage, physical activities, etc. During the summer season glazed spaces will also be very attractive for ordinary occupancy.

A condition for energy conservation is that these spaces are not heated directly but utilize heat loss and possibly excess heat from the adjoining buildings. If they are properly positioned and constructed, they will also function as solar collectors.

The energy reduction potential will vary greatly with the relative size of the spaces, with the system installed, and with possibilities for long term storage. If the glazed space covers relatively large parts of the adjoining buildings, the reduced heat loss from these may be considerable. If in addition a certain minimum temperature can be kept in the glazed space, the need for heating in the adjoining buildings may be minimal.

Abroad such spaces are often used consciously as architectural elements due to their special spatial character. In countries like Norway they may in addition serve several needs resulting from the special climatic conditions.

SINTEF has developed energy conservation systems based on this concept and has tested them in experimental buildings. One example is the three solar energy houses in the Heimdal low energy dwellings project which totals 14 houses. Another example is a day care centre now under development for the local student union.     

Wax Ester Rich Oil From The Marine Crustacean,Calanus finmarchicus,is a Bioavailable Source of EPA and DHA for Human Consumption

Oil from the marine copepod, Calanus finmarchicus, which contains >86 % of fatty acids present as wax esters, is a novel source of n‐3 fatty acids for human consumption. In a randomized, two‐period crossover study, 18 healthy adults consumed 8 capsules providing 4 g of Calanus^® Oil supplying a total of 260 mg EPA and 156 mg DHA primarily as wax esters, or 1 capsule of Lovaza^® providing 465 mg EPA and 375 mg DHA as ethyl esters, each with an EPA‐ and DHA‐free breakfast. Plasma EPA and DHA were measured over a 72 h period (t = 1, 2, 4, 6, 8, 10, 12, 24, 48, and 72 h). The positive incremental area under the curve over the 72 h test period (iAUC_{0‐72 h}) for both EPA and DHA was significantly different from zero (p < 0.0001) in both test conditions, with similar findings for the iAUC_{0–24 h} and iAUC_{0–48 h}, indicating the fatty acids were absorbed. There was no difference in the plasma iAUC_{0–72 h} for EPA + DHA, or DHA individually, in response to Calanus Oil vs the ethyl ester condition; however, the iAUC_{0–48 h} and iAUC_{0–72 h} for plasma EPA in response to Calanus Oil were both significantly increased relative to the ethyl ester condition (iAUC_{0–48 h}: 381 ± 31 vs 259 ± 39 μg*h/mL, p = 0.026; iAUC_{0‐72 h}: 514 ± 47 vs 313 ± 49 μg*h/mL, p = 0.009). These data demonstrate a novel wax ester rich marine oil is a suitable alternative source of EPA and DHA for human consumption.     

Familiarizing Food: Frozen Food Chains,Technology, and Consumer Trust,Norway 1940–1970

This article investigates the relationship between food chains and the production of consumer trust through cases drawn from the introduction of frozen fish fillets in Norway. Specifically, it will discuss how the frozen fish industry worked to create consumer trust in this new food product despite initial skepticism. Conventional ways of building trust such as quality control systems, branding, and marketing are investigated, but in addition to these mechanisms, the article discusses how the frozen fish industry utilized a range of more mundane technologies as trust-producing technologies. By investigating this effort, the article argues that technology is a valuable lens for understanding how consumers are familiarized with new foods.