Multiscale computation for bioartificial soft tissues with complex geometries

The mechanical function of soft collagenous tissues is inherently multiscale, with the tissue dimension being in the centimeter length scale and the underlying collagen network being in the micrometer length scale. This paper uses a volume averaging multiscale model to predict the collagen gel mechanics. The model is simulated using a multiscale component toolkit that is capable of dealing with any 3D geometries. Each scale in the multiscale model is treated as an independent component that exchanges the deformation and average stress information through a scale-linking operator. An arterial bifurcation was simulated using the multiscale model, and the results demonstrated that the mechanical response of the soft tissues is strongly sensitive to the network orientation and fiber-to-fiber interactions.     

Establishing the relevancy of the bookkeeping libraries to thefunctional testing of computer implementations

We address issues related to the definition of faults, errors and failures and their separability, and attribution to the different development processes of computing systems. In particular, we deal with historical databases, which presumably contain certain data (i.e., test failure data) and describe the methodology that can be used to analyze the database and obtain the pertinent information. The validation method may be of particular importance, especially when information from the database needs to be extrapolated for a purpose other than the one for which the database was developed. Our methodology was used to evaluate the historical data collected during the development of the IBM 4381 and 9370 family of computers, and to extrapolate the faults found during the function testing     

Structure and photocatalytic performance of magnetically separable titania photocatalysts for the degradation of propachlor

A magnetic photocatalyst was prepared by modification of TiO₂ nanoparticles (Degussa P25) with nanocrystalline γ-Fe₂O₃ nanoparticles through a protective lining made up of two oppositely charged polyelectrolytes. As-prepared magnetically separable photocatalysts differing in γ-Fe₂O₃ loading (3, 8, 13, 20 and 30 wt.%) were characterized by XRD, TEM, thermal analysis, Mössbauer and magnetic measurements. The photocatalytic efficiency of the nanocomposite catalysts was evaluated using a chloroacetanilide herbicide (propachlor) in water as model compound. The primary degradation of propachlor followed pseudo-first-order kinetics according to the Langmuir–Hinshelwood model. Generally, all magnetic photocatalysts exhibit good catalytic activity towards organic pollutants, do not suffer from photodissolution and can be reused several times without any decrease in their photocatalytic activity.     

Study of the removal of dichlorvos and dimethoate in a titanium dioxide mediated photocatalytic process through the examination of intermediates and the reaction mechanism

The photocatalytic oxidation of two selected organophosphorous insecticides (dichlorvos and dimethoate) has been investigated. The aim of the study was the identification of the intermediates that are formed during photocatalytic treatment. Intermediate products from the slurry system were identified by means of solid-phase extraction (SPE) coupled to gas chromatography-mass spectroscopy techniques (GC-MS). Nine possible by-products were identified for dimethoate and three for dichlorvos. A proposed degradation pathway for each insecticide is presented, involving mainly oxidation and dealkylation reactions. The results demonstrated that some of the transient intermediates formed (oxon derivatives, disulfide, chlorinated fragments), were more toxic compared to parent compounds whereas most of them are less toxic than the parent compounds.     

Optimum torsion axis to multistorey buildings by using the continuous model of the structure

The present article pertains to the definition and properties of the optimum torsion axis of flexural‐shear multistorey systems, employing the continuous model of the structure. It is known that, in the general case of a multistorey building, it is not possible to define the real vertical elastic axis (as well as the centre of stiffness) of the building. However, in this case it is possible to define the fictitious vertical elastic axis of the building, which plays the same part as the real elastic axis. In the present article, we use the theory of the continuous model of the structure for the definition of the fictitious vertical elastic axis from a closed mathematical equation. The continuous model of the structure surpasses the discrete respective model in the qualitative comprehension of the response of multistorey tall systems. On the contrary, the discrete model surpasses the continuous model in the accuracy of calculations, but in the present article this is of lesser importance than the qualitative comprehension. Consequently, it is proved that the fictitious vertical elastic axis also constitutes the optimum torsion axis of the building, and at the same time the characteristic properties of the axis in question are set off. Copyright © 2004 John Wiley & Sons, Ltd.     

Structure and photocatalytic performance of TiO2/clay nanocomposites for the degradation of dimethachlor

In the present study TiO₂/clay composites were synthesized by dispersion of TiO₂ on the surfaces of a natural montmorillonite and a synthetic hectorite in order to increase the sorption ability of TiO₂ and therefore its photocatalytic action. Six materials with different loading in TiO₂ (15, 30 and 55 wt%) were prepared and characterized by several analytical techniques including XRD, BET and SEM analysis. The synthetic procedure allows the development of delaminated layers for hectorite–TiO₂ samples, while in the case of montmorillonite–TiO₂ composites we have the formation of a more lamellar-like aggregation. It was found that, the greater the percentage of TiO₂, the greater the pore volume and the specific surface area of the montmorillonite–TiO₂ samples. On the contrary, in the case of hectorite–TiO₂ samples, as the content of TiO₂ increases, the surface area and pore volume decreases. The photocatalytic efficiency of the nanocomposite catalysts was evaluated using a chloroacetanilide herbicide (dimethachlor) in water as model compound. The primary degradation of dimethachlor followed pseudo-first-order kinetics according to the Langmuir–Hinshelwood model. All supported catalysts exhibit good photodegradation efficiency and their overall removal efficiency per mass of TiO₂ was better than that of bare TiO₂ produced by the sol–gel method. In conclusion, together with their good sedimentation ability the composite materials could be considered as a promising alternative for the removal of organic water contaminants.     

A fuzzy reasoning database question answering system

Describes a question-answering system based on fuzzy logic. The proposed system provides the capability to assess whether a database contains information pertinent to a subject of interest by evaluating each comment in the database via a fuzzy evaluator that attributes a fuzzy membership value indicating its relationship to the subject. An assessment is provided for the database as a whole regarding its pertinence to the subject of interest, and consequently comments that are considered irrelevant to the subject may be discarded. The system has been developed for the examination of databases that were created during the development of the IBM 4381 computer systems, for bookkeeping purposes, to assess whether such databases contain information pertinent to the functional changes that occurred during the development cycle. The system, however, can be applied with minimal changes to a variety of circumstances, provided that the fundamental assumptions for the development of the membership functions are respected in the new application. Its applicability, without modifications, assuming the same subject of interest, is granted for databases comprising similar characteristics to that of the original database for which the system has been developed     

Multivariate experimental design for the photocatalytic degradation of imipramine: Determination of the reaction pathway and identification of intermediate products

Multivariate experimental design was applied to the degradation of imipramine solutions under simulated solar irradiation. The efficiency of photocatalytic degradation was determined from the analysis of the following parameters: H₂O₂, Fe^(II) and TiO₂ concentrations. Experimental data were then fitted using artificial neural networks (ANNs). The findings indicate that ANN provided excellent predictive performance while the influence of each parameter on the variable studied was assessed, TiO₂ being the most significant factor, followed by H₂O₂ and Fe^(II).TOC profile shows an initial sharp decrease within 4 h of irradiation (almost 75% of the organic carbon was mineralized) and until 24h complete mineralization is achieved. Nitrogen is mainly transformed into ammonium ions (almost 90% of the stoichiometric amount) and in a negligible extent into nitrate ions.GC/MS and LC/MS were brought to bear in assessing the temporal course of the photocatalyzed process. A first pathway involves the hydroxylation, that is confined to the dibenzodiazepine moiety or the methyl groups. Another route proceeds through the oxidation of the dibenz[azepine] moiety, with the formation of the ketoderivative. Afterwards, the detachment of the aminoalkylic chain occurs. A parallel transformation involves aminoalkylic chain, with the partial or total detachment of the propylic chain.Microtox bioassay (Vibrio fischeri) was also employed in evaluating the ecotoxicity of solutions treated by photocatalysis. Results clearly demonstrate the efficiency of the photocatalytic process in the detoxification of the irradiated solution.     

Continuous ethanol production from carob pod extract by immobilized Saccharomyces cerevisiae in a packed-bed reactor

The continuous production of ethanol from carob pod extract by immobilized Saccharomyces cerevisiae in a packed-bed reactor has been investigated. At a substrate concentration of 150 g dm^?3, maximum ethanol productivity of 16 g dm^?3 h^?1 was obtained at D = 0·4 h^?1 with 62·3% of theoretical yield and 83·6% sugars′ utilization. At a dilution rate of 0·1 h^?1, optimal ethanol productivity was achieved in the pH range 3·5–5·5, temperature range 30–35·C and initial sugar concentration of 200 g dm^?3. Maximum ethanol productivity of 24·5 g dm^?3 h^?1 was obtained at D = 0·5 h^?1 with 58·8% of theoretical yield and 85% sugars′ utilization when non-sterilized carob pod extract containing 200 g dm^?3 total sugars was used as feed material. The bioreactor system was operated at a constant dilution rate of 0·5 h^?1 for 30 days without loss of the original immobilized yeast activity. In this case, the average ethanol productivity, ethanol yield (% of theoretical) and sugars′ utilization were 25 g dm^?3 h^?1, 58·8% and 85·5%, respectively.