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排序方式: 共有314条查询结果,搜索用时 11 毫秒
1.
The enzymatic degradation of poly(N‐isopropyl acrylamide) (PNIPAM) grafted to carboxymethylcellulose (CMC) copolymers with a cellulasic preparation (Trichoderma viride) was studied. The enzymatic activity of the cellulasic preparation against CMC and the grafted copolymers was determined by the Petterson–Porath method, while their reduced viscosity variation in the presence of the same preparation was also followed. It has been shown that the enzymatic degradation behavior depends on the copolymer composition and the reaction temperature. Reducing sugars analysis showed that the experimental values for the grafted copolymers were higher than the calculated ones. At 50°C, the enzymatic reaction is completed in about 20 min for the copolymers, whereas for CMC it takes more than 40 min. It can be concluded that their enzymatic degradation is facilitated by the presence of the PNIPAM grafts. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 87: 1383–1386, 2003 相似文献
2.
The main object of the present paper is to discuss some extensions of certain integral operators and to obtain their order of convexity. Several other closely related results are also considered. 相似文献
3.
Daniela PatrascuAuthor VitaeIulia DavidAuthor Vitae Vasile DavidAuthor VitaeConstantin MihailciucAuthor Vitae Ioan StamatinAuthor VitaeJean CiureaAuthor Vitae Livia NagyAuthor VitaeGéza NagyAuthor Vitae Anton Alexandru CiucuAuthor Vitae 《Sensors and actuators. B, Chemical》2011,156(2):731-736
Iron(II) phthalocyanine (FePc) modified multi-wall carbon nanotubes paste electrodes (MWCNTPEs) were used as voltammetric sensors to selectively detect dopamine (DA) in the presence of serotonin (5-HT). The electrochemical behavior of DA at the new modified electrode was investigated using CV. The enhanced current response of DA indicates that FePc modification of the MWCNTPE surface results in a high catalytic activity for the redox reaction of DA. Differential pulse voltammetry was applied in detection of DA and 5-HT at FePc-MWCNTPE. The method parameters were optimized. Detection limit of 2.05 × 10−7 M was obtained for DA by using the electrocatalytic oxidation signal corresponding to the FeII/FeIII redox process. The separation between the peak potentials of DA and 5-HT is 170 mV which is large enough for the simultaneously, selective determination of the two chemical species in their mixtures. There was no electrochemical response for ascorbic acid (AA) added in the sample. The monoamine neurotransmitter measuring method has been tested in analyzing deproteinized serum samples. 相似文献
4.
5.
Sarni Suhaila Rahim Chrisina Jayne Vasile Palade James Shuttleworth 《Neural computing & applications》2016,27(5):1149-1164
Regular eye screening is essential for the early detection and treatment of the diabetic retinopathy. This paper presents a novel automatic screening system for diabetic retinopathy that focuses on the detection of the earliest visible signs of retinopathy, which are microaneurysms. Microaneurysms are small dots on the retina, formed by ballooning out of a weak part of the capillary wall. The detection of the microaneurysms at an early stage is vital, and it is the first step in preventing the diabetic retinopathy. The paper first explores the existing systems and applications related to diabetic retinopathy screening, with a focus on the microaneurysm detection methods. The proposed decision support system consists of an automatic acquisition, screening and classification of diabetic retinopathy colour fundus images, which could assist in the detection and management of the diabetic retinopathy. Several feature extraction methods and the circular Hough transform have been employed in the proposed microaneurysm detection system, alongside the fuzzy histogram equalisation method. The latter method has been applied in the preprocessing stage of the diabetic retinopathy eye fundus images and provided improved results for detecting the microaneurysms. 相似文献
6.
Vasile Dragan Author vitae 《Automatica》2011,47(1):122-126
In this paper, the problem of robust H∞ control is investigated for sampled-data systems with probabilistic sampling. The parameter uncertainties are time-varying norm-bounded and appear in both the state and input matrices. For the simplicity of technical development, only two different sampling periods are considered whose occurrence probabilities are given constants and satisfy Bernoulli distribution, which can be further extended to the case with multiple stochastic sampling periods. By applying an input delay approach, the probabilistic sampling system is transformed into a continuous time-delay system with stochastic parameters in the system matrices. By linear matrix inequality (LMI) approach, sufficient conditions are obtained, which guarantee the robust mean-square exponential stability of the system with an H∞ performance. Moreover, an H∞ controller design procedure is then proposed. An illustrative example is included to demonstrate the effectiveness of the proposed techniques. 相似文献
7.
In this paper, a process for 200 μm high-aspect-ratio micro-optical (HARM) structures fabricated by deep X-ray lithography
(DXRL) of polymethylislesuioane-based spin-on glass (SOG) thick films is presented. The SOG material used in the whole procedures
is polymethylsilsesquioxane (GR650), which is a kind of sol-gel derived material and can be cured at a reasonable low temperature
(75 °C). A technique to cast thick GR650 films was established in the overall process. After consolidation, the GR650 thick
films were machined to reach 200 μm uniformly. Then, as negative resists, the GR650 thick films were patterned directly by
DXRL. X-ray irradiated regions can be selectively retained with high structural resolution by development in an organic solvent,
such as methanol. Parameter screening was done to find minimum and maximum doses needed for patterning/cross-linking, to vary
development time, and to explore different film thickness. The whole process is a novel of technique to create HARM structures
based on SOG materials without using molds. This technique can be extended to considerably larger structural heights. Surface
and bulk compositions of the irradiated films were measured by XPS and Fourier transform infrared spectroscopy. Surface quality
by roughness testing system (WYKO RST) was investigated to fabricate the microstructure with a high-accuracy surface.
Received: 31 October 2001/Accepted: 23 January 2002
This work was partially supported by NSF/LEQSF (2001-04)-RII-02 grant “Micro/Nanodevices for Physical, Chemical and biological
Sensors”. 相似文献
8.
Angela Cozma Nicolae Dan Sporis Andrada Luciana Lazar Andrei Buruiana Andreea Maria Ganea Toma Vlad Malinescu Bianca Mihaela Berechet Adriana Fodor Adela Viviana Sitar-Taut Vasile Calin Vlad Vasile Negrean Olga Hilda Orasan 《International journal of molecular sciences》2022,23(18)
Immune checkpoint inhibitors (ICIs) are an important advancement in the field of cancer treatment, significantly improving the survival of patients with a series of advanced malignancies, like melanoma, non-small cell lung cancer (NSCLC), hepatocellular carcinoma (HCC), renal cell carcinoma (RCC), and Hodgkin lymphoma. ICIs act upon T lymphocytes and antigen-presenting cells, targeting programmed cell death protein 1 (PD1), programmed cell death protein ligand 1 (PD-L1), and cytotoxic T-lymphocyte antigen 4 (CTLA-4), breaking the immune tolerance of the T cells against malignant cells and enhancing the body’s own immune response. A variety of cardiac-adverse effects are associated with ICI-based treatment, including pericarditis, arrhythmias, cardiomyopathy, and acute coronary syndrome, with myocarditis being the most studied due to its often-unexpected onset and severity. Overall, Myocarditis is rare but presents an immune-related adverse event (irAE) that has a high fatality rate. Considering the rising number of oncological patients treated with ICIs and the severity of their potential adverse effects, a good understanding and continuous investigation of cardiac irAEs is of the utmost importance. This systematic review aimed to revise recent publications (between 2016–2022) on ICI-induced cardiac toxicities and highlight the therapeutical approach and evolution in the selected cases. 相似文献
9.
Rbert Szab Csaba Pl Rcz Francisc Vasile Dulf 《International journal of molecular sciences》2022,23(14)
In recent years, there has been considerable interest in icariin (ICA) and its derivates, icariside II (ICS) and icaritin (ICT), due to their wide range of potential applications in preventing cancer, cardiovascular disease, osteoporosis, delaying the effects of Alzheimer’s disease, treating erectile dysfunction, etc. However, their poor water solubility and membrane permeability, resulting in low bioavailability, dampens their potential beneficial effects. In this regard, several strategies have been developed, such as pharmaceutical technologies, structural transformations, and absorption enhancers. All these strategies manage to improve the bioavailability of the above-mentioned flavonoids, thus increasing their concentration in the desired places. This paper focuses on gathering the latest knowledge on strategies to improve bioavailability for enhancing the efficacy of icariin, icariside II, and icaritin. We conclude that there is an opportunity for many further improvements in this field. To the best of our knowledge, no such review articles scoping the bioavailability improvement of icariin and its derivates have been published to date. Therefore, this paper can be a good starting point for all those who want to deepen their understanding of the field. 相似文献
10.