The Plug & Play Reactor: A Highly Flexible Device for Heterogeneous Reactions in Continuous Flow

The so‐called plug & play reactor is a novel reaction device with exchangeable reaction segments as well as modules for heating/cooling and mixing. Its performance is demonstrated for two model processes: the production of acetylsalicylic acid with a fixed bed of commercial ion‐exchange particles and a Suzuki‐Miyaura cross‐coupling with a solid Pd‐catalyst developed by us. The reaction progress was monitored by inline UV‐vis spectroscopy and compared with offline HPLC. The novel set‐up leads to quantitative yields and selectivity as well as to an improved practicability of the processes.