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1.
In this study, the anti-atherosclerotic properties of three marine phospholipids (MPLs) extracts from fishery by-products including codfish roe, squid gonad, and shrimp head are verified. Their effects on key factors involved in atherosclerosis are examined and compared to explore whether the differences in their constitutions lead to the differences in the function. All three MPLs dampen oxidation of low- density lipoproteins (LDL) in vitro. Treating RAW264.7 macrophages and HUVECs endothelial cells with each MPLs ranging 10–100 µg mL−1 does not decrease cell viability, yet ox-LDL caused cytotoxicity of both cells are alleviated by 50 or 100 µg mL−1 MPLs treatment. In addition, the three MPLs reduce ox-LDL induced macrophage foam-like transition, mainly through inhibition of lipid uptake. Of the three MPLs, the one from squid gonad exhibits the best effect. On the other hand, all three MPLs modulate inflammatory responses, equally, by inhibiting the adhesion of monocytes to endothelial cells, and decreasing secretion of pro-inflammatory cytokines IL-6 and MCP-1. Using a high-cholesterol diet induced zebrafish model, it is found that all three MPLs, especially the one from squid gonad, alleviates cholesterol accumulation in early plaques, and decreases total cholesterol as well as lipid peroxide in vivo. Practical Applications: As a way of making the best of the increasingly scarce marine resources, valuable lipid components can be recovered from by-products and wastes from the fishery industry. Here, we tested the anti-atherosclerotic effects and the mechanisms of three MPLs extracted from codfish roe, squid gonad, and shrimp head. Our study provides further evidence that marine phospholipids extracted from fishery by-products could protect against atherosclerosis, and helps to elucidate the structure-function relationship of MPLs.  相似文献   
2.
The capture of particles by charged droplets was simulated by considering the electrostatic interactions of droplet-droplet and droplet-particle. The results indicate that the electrostatic repulsion between droplets leads to a dynamic accumulation mode of particles. However, the droplet spacing has an insignificant effect on the capture efficiency when the electrostatic deposition predominates. The increase of droplet charge remarkably improves the capture efficiency, in which the capture of fine particles accounts for the largest proportion. Compared to the droplet charge, the droplet size shows a limited improvement in the capture efficiency. Reducing the droplet velocity prolongs the capture time instead of enhancing the capture capacity per unit time, thereby improving capture efficiency.  相似文献   
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Artificial nitrogen fixation is emerging as a promising approach for synthesis of ammonia at mild conditions. Inspired by biological nitrogen fixation based on bacteria containing iron, zinc doped Fe2O3 nanoparticles are proposed as an efficient and earth abundant electrocatalyst for converting N2 to NH3. In neutral media, it achieves a maximum Faradaic efficiency (FE) of 10.4% and a large NH3 yield rate of 15.1 μg h?1 mg?1cat. at ?0.5 V vs. reversible hydrogen electrode. This catalyst also exhibits excellent selectivity and stability. Theoretical calculations suggest the reaction follows the associative enzymatic mechanism and it has a barrier of as low as 0.68 eV.  相似文献   
5.
低渗低温低压水敏性储气层压裂改造技术研究与应用   总被引:1,自引:0,他引:1  
低渗低温低压水敏性储气层因压裂液快速破胶困难、黏土膨胀水敏伤害严重和压后压裂液返排动力不足等因素,使得压裂增产面临诸多难题。针对上述难题进行了技术攻关,形成了弱交联、低温活化剂与超量破胶剂的低温储层快速破胶技术、有机盐与无机盐双元体系复合防膨技术以及高比例液氮全程助排的排液技术。该压裂增产改造技术使牛101井头屯河组首次获得工业油气流,扩展了三塘湖盆地勘探空间。  相似文献   
6.
玻璃碳电极(GCE)用激光脉冲照射处理后,电化学反应行为发生很大变化。背景电流减小,Fe3+/Fe2+氧化还原电对的电极反应速率显著提高,抗坏血酸(AA)在电极上呈现明显的吸附作用。  相似文献   
7.
NK-EH500调质钢爆炸硬化的冲击动力学研究   总被引:1,自引:0,他引:1  
通过试验并运用爆炸冲击动力学理论NK-EH500调质钢爆炸硬化进行了深入的研究,结果表明,金属材料存在硬化极限,调整炸药组成改变爆炸硬化可以满足不同金属材料的硬化要求,隔离式爆炸硬化有利于保护硬化工件外观的完整性,本研究对拓展爆炸硬化在实践中的应用领域具有重要的理论指导意义。  相似文献   
8.
捞油车自动排绳控制装置   总被引:3,自引:2,他引:1  
针对部分油田采用捞油的采油方式,介绍的自动排绳装置,是双通道化例闭环控制系统,特点是按照输入的给定、误差信号方向、大小变化,输出信号的方向、大小随之变化,自动跟踪,自动补偿,输出速度连续无级变速,可以手动和自动工作。  相似文献   
9.
A novel series of temperature‐sensitive poly[(N‐isopropylacrylamide)‐co‐(ethyl methacrylate)] (p(NIPAM‐co‐EMA)) microgels was prepared by the surfactant‐free radical polymerization of N‐isopropylacrylamide (NIPAM) with ethyl methacrylate (EMA). The shape, size dispersity and volume‐phase transition behavior of the microgels were investigated by transmission electron microscopy (TEM), ultraviolet–visible (UV–Vis) spectroscopy, dynamic light scattering (DLS) and differential scanning calorimetry (DSC). The transmission electron micrographs and DLS results showed that microgels with narrow distributions were prepared. It was shown from UV–Vis, DLS and DSC measurements that the volume‐phase transition temperature (VPTT) of the p(NIPAM‐co‐EMA) microgels decreased with increasing incorporation of EMA, but the temperature‐sensitivity was impaired when more EMA was incorporated, causing the volume‐phase transition of the microgels to become more continuous. It is noteworthy that incorporation of moderate amounts of EMA could not only lower the VPTT but also enhance the temperature‐sensitivity of the microgels. The reason for this phenomenon could be attributed to changes in the complicated interactions between the various molecules. Copyright © 2004 Society of Chemical Industry  相似文献   
10.
清涧河流域不同水土保持措施配置下蓄水拦沙效益分析   总被引:5,自引:0,他引:5  
从分析清涧河流域不同年代水土保持措施配置人手,以蓄水拦沙效益为研究目标,探讨了水土保持措施优化配置问题。分析认为:水土保持措施配置与蓄水拦沙效益是密切相关的,淤地坝在水土保持措施配置中应占有合理比重,坡面治理措施配置中需进一步加大封禁治理比例。  相似文献   
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