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排序方式: 共有224条查询结果,搜索用时 15 毫秒
1.
H. -C. Chiao H. -L. Lin X. -T. Li C. -X. Ding 《Journal of Thermal Spray Technology》1992,1(2):111-115
Diamond growth with rates up to 100 to 140 μm/hr was achieved using an oxygen-acetylene combustion spraying technique in an
atmospheric environment. Investigations on the processing indicated that the gas flow ratio, substrate position, substrate
temperature, temperature distribution, and substrate pretreatment were the most important factors affecting the growth of
diamond crystals. Evaluation by means of X-ray diffraction, Raman spectroscopy, scanning electron microscopy, and electron
probe microanalysis showed that the synthesized diamond was nearly perfect in morphology, structure, and purity. 相似文献
2.
Abnormal wave propagation in passive media 总被引:1,自引:0,他引:1
Mojahedi M. Malloy K.J. Eleftheriades G.V. Woodley J. Chiao R.Y. 《IEEE journal of selected topics in quantum electronics》2003,9(1):30-39
Abnormal velocities in passive structures such as one-dimensional (1-D) photonic crystals and a slab having a negative index of refraction are discussed. In the case of 1-D photonic crystal, the frequency- and time-domain experiments for waves tuned to the bandgap of the photonic crystal demonstrate a positive group velocity exceeding the speed of light in vacuum (superluminal). In the case of a medium with negative index of refraction, our theoretical studies show that such a medium can support positive group and negative phase velocities (backward waves), as well as negative group and negative phase velocities. The meaning of superluminal group velocity and negative group velocity, or equally, positive superluminal group delay and negative group delay, are discussed. It is shown that despite their counterintuitive meaning there are no contradictions with the requirements of relativistic causality (Einstein causality). To clearly demonstrate this, the important subject of the "front" is reintroduced. 相似文献
3.
The scanning tomographic acoustic microscope (STAM) was proposed in 1982 as a method of improving the resolution capability of the scanning laser acoustic microscope (SLAM) based on the principles of tomography. By modifying the SLAM with a quadrature detector, tomographic projections that contain both the amplitude and phase information of the scattered wavefield can be acquired. Subsequently, multiple projections acquired with different incident waves are combined using the "back-and-forth" propagation algorithm to form the tomographic reconstruction. The first STAM reconstructions have been obtained to experimentally demonstrate the superior resolution capability of the STAM over the SLAM. In this paper, the implementation of the STAM is described, and experimental reconstructions of multiple-layer specimens are demonstrated. 相似文献
4.
Immobilization of Photo‐Immunoconjugates on Nanoparticles Leads to Enhanced Light‐Activated Biological Effects 下载免费PDF全文
Huang‐Chiao Huang Michael Pigula Yanyan Fang Tayyaba Hasan 《Small (Weinheim an der Bergstrasse, Germany)》2018,14(31)
The past three decades have witnessed notable advances in establishing photosensitizer–antibody photo‐immunoconjugates for photo‐immunotherapy and imaging of tumors. Photo‐immunotherapy minimizes damage to surrounding healthy tissue when using a cancer‐selective photo‐immunoconjugate, but requires a threshold intracellular photosensitizer concentration to be effective. Delivery of immunoconjugates to the target cells is often hindered by I) the low photosensitizer‐to‐antibody ratio of photo‐immunoconjugates and II) the limited amount of target molecule presented on the cell surface. Here, a nanoengineering approach is introduced to overcome these obstacles and improve the effectiveness of photo‐immunotherapy and imaging. Click chemistry coupling of benzoporphyrin derivative (BPD)–Cetuximab photo‐immunoconjugates onto FKR560 dye‐containing poly(lactic‐co‐glycolic acid) nanoparticles markedly enhances intracellular photo‐immunoconjugate accumulation and potentiates light‐activated photo‐immunotoxicity in ovarian cancer and glioblastoma. It is further demonstrated that co‐delivery and light activation of BPD and FKR560 allow longitudinal fluorescence tracking of photoimmunoconjugate and nanoparticle in cells. Using xenograft mouse models of epithelial ovarian cancer, intravenous injection of photo‐immunoconjugated nanoparticles doubles intratumoral accumulation of photo‐immunoconjugates, resulting in an enhanced photoimmunotherapy‐mediated tumor volume reduction, compared to “standard” immunoconjugates. This generalizable “carrier effect” phenomenon is attributed to the successful incorporation of photo‐immunoconjugates onto a nanoplatform, which modulates immunoconjugate delivery and improves treatment outcomes. 相似文献
5.
We have developed a compensated capacitive pressure and temperature sensor for kraft pulp digesters (pH 13.5, temperatures
25–175°C reaching a local maximum of 180°C and pressures up to 2 MPa). The gauge capacitive pressure sensor was fabricated
by bonding silicon and Pyrex chips using a high temperature, low viscosity UV (ultraviolent) adhesive as the gap-controlling
layer and heat curing adhesive as the bonding agent. A simple chip bonding technique, involving insertion of the adhesive
into the gap between two chips was developed. A platinum thin-film wire was patterned on top of a silicon chip to form a resistance
temperature detector (RTD) with a nominal resistance of 1,500 Ω. A silicon dioxide layer and a thin layer of Parylene were
deposited to passivate the pressure sensor diaphragm and the sensors were embedded into epoxy for protection against the caustic
environment in kraft digesters. The sensors were tested up to 2 MPa and 170°C in an environment chamber. The maximum thermal
error of ±1% (absolute value of ±20 kPa) full scale output (FSO) and an average sensitivity of 0.554 fF/kPa were measured.
Parylene-coated silicon chips were tested for a full kraft pulping cycle with no signs of corrosion. 相似文献
6.
Fa-Hsyang Chen Jim-Long Her Yu-Hsuan Shao Yasuhiro H Matsuda Tung-Ming Pan 《Nanoscale research letters》2013,8(1):18
In this letter, we investigated the structural and electrical characteristics of high-κ Er2O3 and Er2TiO5 gate dielectrics on the amorphous indium-gallium-zinc-oxide (a-IGZO) thin-film transistor (TFT) devices. Compared with the Er2O3 dielectric, the a-IGZO TFT device incorporating an Er2TiO5 gate dielectric exhibited a low threshold voltage of 0.39 V, a high field-effect mobility of 8.8 cm2/Vs, a small subthreshold swing of 143 mV/decade, and a high Ion/Ioff current ratio of 4.23 × 107, presumably because of the reduction in the oxygen vacancies and the formation of the smooth surface roughness as a result of the incorporation of Ti into the Er2TiO5 film. Furthermore, the reliability of voltage stress can be improved using an Er2TiO5 gate dielectric. 相似文献
7.
8.
A study on the formation of a measurement scale for the environmental quality of Taiwan’s long-term care institutions by the Delphi method 总被引:1,自引:0,他引:1
Yen Ping Hsieh Yen Wen Hsieh Chia Ching Lin Chien Wen Yeh Sing Chiao Chang 《Journal of Housing and the Built Environment》2012,27(2):169-186
This study used a two-round modified Delphi technique with a questionnaire survey in order to reach a consensus for the questionnaire; the survey was conducted from September to December 2009. The six indicators for the environmental quality of long-term care institutions in Taiwan are (1) indoor environmental quality, (2) safety equipment for the prevention and management of disasters occurring in residents?? daily lives, (3) provision for assistive devices for residents?? daily use, (4) provision for privacy and individualized space, (5) provision for comfortable and decorated indoor environments, and (6) provision for social interaction space. The scale included 34 items with an acceptable number of panel members and acceptable construct validity. Panel members all highly approved of Indicators 1, 2, and 6. Although they approved of Indicator 3, they suggested that caregivers at institutions should replace the functions of living assistive devices. They approved of Indicator 5; however, they questioned the method for providing comfortable and decorated environments. They approved of Indicator 4; however, they suggested that private space need not be provided in the living room of the institution. In terms of long-term care institution environments in Taiwan, Indicators 1, 2, and 6 were important for protecting residents?? physical and psychological well-being and improving their social interactions. Indicator 3, although important, could be directly replaced by caregivers. Indicator 5 required more implementation methods, while Indicator 4, the living room of the institution, was considered unnecessary. 相似文献
9.
10.
Yen-Jung Chou Wei-Chih Kan Chieh-Min Chang Yi-Jen Peng Hsien-Yi Wang Wen-Chun Yu Yu-Hsuan Cheng Yu-Rou Jhang Hsia-Wei Liu Jiunn-Jye Chuu 《International journal of molecular sciences》2016,17(9)
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in diabetes mellitus. Oxidative stress, insulin resistance and pro-inflammatory cytokines have been shown to play an important role in pathogeneses of renal damage on type 2 diabetes mellitus (DM). Inonotus obliquus (IO) is a white rot fungus that belongs to the family Hymenochaetaceae; it has been used as an edible mushroom and exhibits many biological activities including anti-tumor, anti-oxidant, anti-inflammatory and anti-hyperglycemic properties. Especially the water-soluble Inonotus obliquus polysaccharides (IOPs) have been previously reported to significantly inhibit LPS-induced inflammatory cytokines in mice and protect from streptozotocin (STZ)-induced diabetic rats. In order to identify the nephroprotective effects of low molecular weight of IOP fraction (LIOP), from the fruiting bodies of Inonotus obliquus, high-fat diet (HFD) plus STZ-induced type 2-like diabetic nephropathy C57BL/6 mice were investigated in this study. Our data showed that eight weeks of administration of 10–100 kDa, LIOP (300 mg/kg) had progressively increased their sensitivity to glucose (less insulin tolerance), reduced triglyceride levels, elevated the HDL/LDL ratio and decreased urinary albumin/creatinine ratio(ACR) compared to the control group. By pathological and immunohistochemical examinations, it was indicated that LIOP can restore the integrity of the glomerular capsules and increase the numbers of glomerular mesangial cells, associated with decreased expression of TGF-β on renal cortex in mice. Consistently, three days of LIOP (100 μg/mL) incubation also provided protection against STZ + AGEs-induced glucotoxicity in renal tubular cells (LLC-PK1), while the levels of NF-κB and TGF-β expression significantly decreased in a dose-dependent manner. Our findings demonstrate that LIOP treatment could ameliorate glucolipotoxicity-induced renal fibrosis, possibly partly via the inhibition of NF-κB/TGF-β1 signaling pathway in diabetic nephropathy mice. 相似文献