A simplified approach to predict part temperature and minimum “safe” cycle time

The largest component of the injection molding cycle is the cooling time. Thus it is highly desirable, to be able to predict what its minimum acceptable value can be. This is becoming even more important with increased competition from regions where the labor cost is low. In an injection molding operation, the mold thermal state changes from its initial value until a quasi steady state is reached. The minimum required cooling time increases with continuous molding until a steady state value is achieved. Improving the mold thermal design will decrease the cooling time thus reducing total cycle time. The overall goal of this work is to develop a simple reliable method to predict a minimum safe cycle time for steady production. In this article, we discuss software capable of simulating the thermal state of the part and mold for multiple injection molding cycles while balancing simulation time with results accuracy. Three case studies are presented, one done in our labs and two on‐site at an automotive manufacturing facility. The three case studies are used to evaluate the ability of the software to predict part surface temperature for continuous molding. We also discuss how this software can be used as the basis to establish the minimum safe cycle time. POLYM. ENG. SCI., 2008. © 2008 Society of Plastics Engineers     

High Helicobacter pylori eradication rate with a 1-week regimen containing ranitidine bismuth citrate

HSR-903 is a newly synthesized quinolone antibacterial agent with low toxicity. The biliary and urinary excretion of unchanged HSR-903, its R-isomer, and their glucuronides was determined after iv bolus administration (5 mg/kg) to normal Sprague-Dawley rats (SDR) and Eisai hyperbilirubinemic mutant rats (EHBR). The values for the biliary excretion clearance of HSR-903 and its glucuronide in EHBR were decreased to approximately 40 and 2% of those in SDR, respectively, whereas the values for the urinary excretion clearance of HSR-903 and its glucuronide were comparable in SDR and EHBR. The biliary excretion clearance values for the R-isomer and its glucuronide were approximately 3 times greater than those for HSR-903. These results demonstrated that the enantiomers of HSR-903 and their conjugates were excreted into bile in a stereospecific manner. The hepatic uptake of [14C]HSR-903 in vivo was evaluated by means of integration plot analysis. The results indicated that the hepatic uptake of [14C]HSR-903 was very fast and was blood flow-limited. To clarify the mechanism of excretion of HSR-903 into bile, the uptake and efflux of [14C]HSR-903 were studied using isolated hepatocytes from SDR and EHBR. The initial uptake of HSR-903 by hepatocytes was temperature-dependent, saturable, and stereospecific. Unlabeled HSR-903 (S-isomer), the R-isomer, grepafloxacin, and sparfloxacin significantly inhibited the uptake of [14C]HSR-903. The efflux of [14C]HSR-903 from hepatocytes from EHBR was significantly slower than that from hepatocytes from SDR. The addition of sodium azide or bromosulfophthalein reduced the efflux of [14C]HSR-903. These results demonstrate that HSR-903 is actively excreted into bile via the canalicular multispecific organic anion transporter, which is deficient in EHBR.     

Properties and process ability of long fiber‐reinforced polymeric composites

The addition of nanoparticles to polymeric matrices has shown great promise for improving mechanical and thermal properties; however, this improvement comes with a decrease of processability. In this study, two different glass fabrics were used. One of them was Windstrand, a stitched equally‐biaxial R‐glass fabric the other was Advantex, a unidirectional glass fiber mat. Both of them are provided by Owens Corning. The mats were sprayed with carbon nanofibers (CNF) on both sides. Mechanical properties of composites manufactured via vacuum‐assisted resin transfer molding were obtained. Permeability, as a measure of processability, of the sprayed glass mats was measured. Mechanical properties are improved, whereas permeability decreases with the addition of CNF. POLYM. COMPOS., 35:655–664, 2014. © 2013 Society of Plastics Engineers     

Preventing active re-identification attacks on social graphs via sybil subgraph obfuscation

Knowledge and Information Systems - Active re-identification attacks constitute a serious threat to privacy-preserving social graph publication, because of the ability of active adversaries to...     

Effect of polyaniline surface modification of carbon nanofibers on cure kinetics of epoxy resin

Polyaniline (PANI) “nanograss” was grown on carbon nanofibers (CNFs). The cure behavior of an epoxy resin with and without unmodified CNFs or PANI modified CNFs was studied by means of non‐isothermal and isothermal differential scanning calorimetry (DSC). CNFs accelerated the reaction of epoxy and diamine. PANI surface modification further increased the reaction rate and the extent of reaction. An autocatalytic cure kinetic model was used to fit the reaction curves. It was found that activation energies of the epoxy reaction decreased in the presence of CNFs and PANI modified CNFs. The observed catalytic effect of CNF and PANI surface coating can be very useful for low temperature cure of large epoxy composite products. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010     

Minimum “safe cycle time”: Selecting the frozen layer thickness

Predicting the minimum safe cycle time in injection molding is complicated by the cyclic nature of the process. The mold thermal state changes with continuous molding until a quasi steady state is achieved. In the first part of these series, we presented and experimentally tested a simple approach to predict part and mold surface temperature during continuous molding. In this work, we evaluate the minimum frozen layer thickness required before the part can be demolded and how the growth of this frozen layer is affected as the mold thermal state changes with continuous molding cycles. Experiments are used to relate the minimum frozen layer thickness to dimensional stability. Based on these experiments, statistical tools are used to select an ejection criterion to obtain a minimum safe cooling time. We show that the ejection criteria should be adjusted depending on the precision required from the molded parts. POLYM. ENG. SCI., 2009. © 2009 Society of Plastics Engineers