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排序方式: 共有1674条查询结果,搜索用时 15 毫秒
1.
Y Ohe ER Podack KJ Olsen Y Miyahara K Miura H Saito Y Koishihara Y Ohsugi T Ohira K Nishio 《Canadian Metallurgical Quarterly》1993,67(5):939-944
HuIL-6 cDNA, cloned into a neomycin resistant conferring expression vector, BMGNeo, was transfected into Lewis Lung Carcinoma (LLC) cells. LLC cells (5 x 10(6) ml-1) transfected with IL-6 cDNA (LLC-IL6) secreted IL-6 into the culture supernatant at a concentration of 9.9 ng ml-1 within 48 h. When 1,000,000 of untransfected LLC, BMGNeo vector transfected LLC (LLC-Neo) or LLC-IL6 cells were transplanted into C57BL/6 mice subcutaneously, the mean +/- s.d. of survival times of these mice were 33.3 +/- 9.7, 34.3 +/- 7.1 and 17.0 +/- 3.1 days, respectively. The survival time of LLC-IL6 cells transplanted mice was significantly shorter than that of LLC (P < 0.01) or LLC-Neo (P < 0.01) cells transplanted mice without a measurable difference of tumour size. Plasma concentration of IL-6 steadily increased in LLC-IL6 transplanted mice. Body weight and serum albumin were significantly lower in LLC-IL6 transplanted mice than in LLC transplanted mice. Mouse IL-1 alpha and mouse TNF-alpha were not detected in the plasma of LLC-IL6 transplanted mice. These data suggested that secretion of IL-6 from LLC cells was unable to alter net tumour growth rate but rather caused a state similar to cachexia without detectable increase of IL-1 alpha and TNF-alpha in the plasma. This state may be responsible for the shortened survival of LLC-IL6 tumour-bearing mice. 相似文献
2.
Shijie Zhu Yutaka Kagawa Jian-Wu Cao Mineo Mizuno 《Metallurgical and Materials Transactions A》2004,35(9):2853-2859
Time-dependent deformation in an enhanced SiC/SiC composite has been studied under constant load at high temperatures of 1200
°C, 1300 °C, and 1400 °C. Creep damage evolution was evaluated by a Young’s-modulus change of partial unloading and microscopic
observation. The addition of the glassy phase in the matrix is very effective for protecting the composite from oxidation.
The transient creep is dominant in creep life at all the temperatures. An empirical equation is proposed to describe creep
behavior of the composite. It is found that creep activation energy increases with creep time at stresses lower than matrix
cracking stress, but the activation energy remains constant at stresses higher than the matrix cracking stress. The creep
strain rate of the composite is considered to be controlled by creep of fibers based on examining the time, strain, stress,
and temperature dependencies of creep strain rates. 相似文献
3.
Yuji Oie Tatsuya Suda Masayuki Murata Hideo Miyahara 《International Journal of Satellite Communications and Networking》1991,9(5):285-303
One of the most promising approaches for high speed networks for integrated service applications is fast packet switching, or ATM (asynchronous transfer mode). ATM can be characterized by very high speed transmission links and simple, hard-wired protocols within a network. To match the transmission speed of the network links, and to minimize the overhead due to the processing of network protocols, the switching of cells is done in hardware switching fabrics in ATM networks. A number of designs have been proposed for implementing ATM switches. Although many differences exist among the proposals, the vast majority of them are based on self-routeing multistage interconnection networks. This is because of the desirable features of multi-stage interconnection networks such as self-routeing capability and suitability for VLSI implementation. Existing ATM switch architectures can be classified into two major classes: blocking switches, where blockings of cells may occur within a switch when more than one cell contends for the same internal link, and non-blocking switches, where no internal blocking occurs. A large number of techniques have also been proposed to improve the performance of blocking and non-blocking switches. In this paper, we present an extensive survey of the existing proposals for ATM switch architectures, focusing on their performance issues. 相似文献
4.
Hirokazu Ikeda Chikara Fukunaga Yutaka Saitoh Masahiro Inoue Junko Yamanaka 《Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment》1996,380(3):618-622
The radiation tolerance for prototype front-end chips designed for a silicon micro-strip detector was examined with a 60Co irradiation source to establish an allowable range of the radiation dose. The irradiated front-end chips were SMA2SH-64A, a 64-channel preamplifier array; SMA2SH-1, a single-channel preamplifier circuit with a comparator; and Control-C, a digital-control chip for the preamplifiers. 相似文献
5.
Yutaka Asako Hisayoshi KamikogaHisashi Nishimura Yoshiyuki Yamaguchi 《International Journal of Heat and Mass Transfer》2002,45(11):2243-2253
Compression is one solution to improve the strength of softwoods. The effective thermal conductivities of compressed Japanese cedars (cryptomeria japonica), which were compressed in the radial direction of the wood, were measured. Both the effective thermal conductivities in the tangential and fiber directions increase proportionally to the density increment due to the compression. However, the thermal conductivity in the radial direction (compression direction) increases slightly with the density increment. Numerical computations were conducted to explain the characteristics of thermal conductivity in the radial direction by using a microscopic heat conduction model for the compressed wood. The numerical results were compared with the measured values. And the physical mechanism of the heat conduction in the compressed woods is discussed. 相似文献
6.
A single loop electrochemical potentiokinetic reactivation test method has been developed for alloy 600 that produces good passivation on all the surfaces, good etching during the reactivation scan and no appreciable pitting. It is able to quantify and discriminate between samples with a wide range of degree of sensitization. The Pa value correlates well with the minimum level of chromium in the depletion regions at the grain boundaries. It has been shown that the width of the attacked regions is much larger than the width of chromium depletion regions and it does not show any direct correlation with either depth or width or with a volume parameter of chromium depletion regions. It has been shown that the chromium carbides are not attacked during the test and that the intragranular regions attacked during the test are the sites of chromium carbides in the grain matrix. A modified Pa parameter is shown to be sensitive down to 7.5 wt% chromium in the depletion regions and indicates that the intragranular carbides have shallower depletion profiles than those at grain boundaries. Comparison of the results of the single loop and the double loop tests showed a good correlation. 相似文献
7.
The effect of Zr on reduction of hardness and microstructure in an FS weld of equal channel angular-pressed Al alloy was investigated. Zr addition to Al suppressed dynamic recovery in the thermomechanically affected zone and enabled retention of the high hardness of the ECA-pressed material throughout the weld. 相似文献
8.
In recent years the requirement for the reduction of energy consumption has been increasing to solve the problems of global warming and the shortage of petroleum resources. For example, in the power generation field, as thermal power generation occupied 60% of the power generation demand, considerable improvement of the thermal efficiency is required. This paper describes the pressure drop characteristics of finned tube banks used for heat exchangers in thermal power generation that were clarified by testing serrated finned tube banks with different fin heights for improved heat transfer and conventional spiral finned tube banks with different fin heights, and an equation to predict pressure drop which is necessary for the heat exchanger design is proposed. © 2006 Wiley Periodicals, Inc. Heat Trans Asian Res, 35(3): 179–193, 2006; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/htj.20112 相似文献
9.
When West meets East: Contributions of Eastern traditions to the future of psychotherapy. 总被引:1,自引:0,他引:1
Bankart C. Peter; Koshikawa Fusako; Nedate Kaneo; Haruki Yutaka 《Canadian Metallurgical Quarterly》1992,29(1):141
Discusses 2 interrelated traditions as they are reflected in contemporary and traditional approaches to psychotherapy in Japan. One uses various meditational and self-focusing instructional sets whose common goal is to facilitate the slowing down, deepening, and clearer focusing of sensory and interpersonal awareness. The 2nd tradition focuses on physical self-regulation and autonomic self-control through exercises that foster enhanced voluntary control over physical states and processes. Eastern psychology offers a set of practices that help the individual overcome the inherent selfishness of his/her isolated experience. The goals of such work include recognition of gratitude to important people in the client's life, rediscovery of the joy of meaningful work, and the experience of a unifying cosmic consciousness. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
10.
A series of Mo–TiC alloys were heated in vacuum at 2473 K for 36 ks. First grain growth behavior was observed using a scanning electron microscope. Then effects of TiC addition on the strengths and ductility at low temperature were discussed from the viewpoints of chemical composition and grain structure.
Materials with TiC additions of not larger than 0.1% demonstrated a single-crystalline grain structure. Both yield and maximum strengths increased by TiC addition and consequently ductility was improved. 相似文献