Immune response to an intercalated enhanced inactivated polio vaccine/oral polio vaccine programme in Israel: impact on the control of poliomyelitis

A combined enhanced inactivated polio vaccine (EIPV) and oral polio vaccine (OPV) programme was introduced in Israel in 1990, with the purpose of providing a solution to the persistent polio morbidity in spite of a 30 year long OPV programme. The schedule comprised two doses of EIPV administered at the age of 2 and 4 months, intercalated with two doses of OPV at 4 and 6 months, followed by a reinforcing dose with the two vaccines simultaneously administered at 12 months. The 5-year evaluation of the programme included: the assessment of clinical suspicions of polio, early immune response in successive cohorts administered the new schedule, dynamics of the immune profile in a cohort followed up to the age of 5, and monitoring of wild poliovirus excretion in sewage specimens collected in 25 permanent sites throughout Israel as well as from the Palestinian Authority. No paralytic polio cases associated with a wild or vaccinal poliovirus strain were detected since the introduction of the programme. At the age of 4 months, one week after administration of the second EIPV and first OPV dose, 100% seropositivity and high geometric mean titres (GMTs) of neutralizing antibody (NA) to the three vaccinal and to the wild poliovirus type 1, responsible for the 1988 polio outbreak, were observed. No change in percent of seropositivity occurred between the age of 6 and 12 months. Thirty days after the IPV and OPV reinforcing doses, GMTs to each of the four poliovirus strains were > or = 3037. Up to the age of 5, the seropositivity was unchanged. After a 2.5-10-fold decline in the first year following the completion of the programme, GMTs to the three vaccinal and the wild poliovirus strain levelled off at rather high values, considered protective. Between 1990 and 1995, 16 wild poliovirus type 1 strains were isolated in three separate episodes in Gaza Strip sewage and once only in one Israeli site very close to Gaza City. The rapidly established, high and persistent NA titre to the vaccinal and wild poliovirus strains and the presence of immunological memory are indicative of high individual protection throughout the first 5 years of life. The only one-time introduction, without circulation, of a wild poliovirus strain in a single Israeli settlement suggests community protection. The intercalated programme offers a contribution to polio eradication by providing a solution to the primary and secondary failure associated with OPV, as well as to the control of vaccine-associated paralytic poliomyelitis.     

Acute public health consequences associated with hazardous substances released during transit, 1993-2000

Massive quantities of hazardous substances are transported each day throughout the United States. While most arrive safely at their destination, uncontrolled releases of substances in transit do occur and have the potential of causing acute public health consequences for those individuals at or near the release. Data from 16 state health departments participating in the Agency for Toxic Substances and Disease Registry's (ATSDR) Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to determine the public health consequences that occurred from actual releases in transit. Of the 9392 transportation events analyzed, 9.1% resulted in 2008 victims, including 115 deaths. The population groups injured most often were employees and the general public. The most common injury sustained was respiratory irritation. Evacuations were ordered in 5.5% of events effecting at least 63,686 people. Human error and equipment failure were the most common factors leading to events. These findings underscore the importance of job safety training, community planning, and effective emergency response to prevent adverse public health consequences from occurring or lessen their effect on the public.     

Words, music, and other measures: Predicting the repertoire popularity of 597 Schubert lieder.

To address the venerable aesthetic question of the relative importance of music and words, musical and textual characteristics were used to predict recording counts of 597 Franz Schubert lieder. Predictors included career variables (age and concurrent productivity), "whole song" variables (e.g., performance duration, structural complexity, major vs. minor key), thematic measures of the first six notes of the vocal incipit (e.g., melodic and rhythmic originality), poet variables (Goethe, Schiller, etc.), and text variables (computer content analysis measures of primordial and conceptual thought and positive and negative emotions). Many correlations between predictors were small but reliable; career variables accounted for most strong correlations. A 45-predictor regression model was highly significant (R2 = .63), with 13 reliable (p     

Coping, locus of control, social support, and combat-related posttraumatic stress disorder: A prospective study.

We examined the relations between coping, locus of control, and social support and combat-related posttraumatic stress disorder (PTSD). The sample consisted of 262 Israeli soldiers who suffered a combat stress reaction episode during the 1982 Lebanon war and were followed 2 and 3 years after their participation in combat. Cross-sectional analyses revealed significant relations between locus of control, coping, and social support and PTSD at the two points of assessment. Changes in PTSD from Time 1 to Time 2 were also associated with changes in coping. We discuss theoretical and methodological implications of the findings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The relationships between posttraumatic stress symptom clusters and marital intimacy among war veterans.

This study examined (a) the relationships between posttraumatic stress disorder (PTSD) symptom clusters and marital intimacy among Israeli war veterans and (b) the role of self-disclosure and verbal violence in mediating the effects of PTSD avoidance and hyperarousal symptoms on marital intimacy. The sample consisted of 219 participants divided into 2 groups: ex-prisoners of war (ex-POWs; N = 125) and a comparison group of veterans who fought in the same war but were not held in captivity (N = 94). Ex-POWs displayed higher levels of PTSD symptoms and verbal violence and lower levels of self-disclosure than did controls. Although ex-POWs and controls did not differ in level of marital intimacy, they did, however, present a different pattern of relationships between PTSD clusters and intimacy. In ex-POWs, self-disclosure mediated the relations between PTSD avoidance and marital intimacy. Verbal aggression was also found via indirect effect of hyperarousal on marital intimacy. The results point to the importance of self-disclosure and verbal violence as interpersonal mechanisms for the relations between posttraumatic symptoms on marital intimacy of ex-POWs. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The thermogenic center in social wasps

In the social wasps Vespa orientalis and Paravespula germanica (Hymenoptera, Vespinae), a thermogenic center has been found in the dorsal part of the first thoracic segment. The temperature in this region of the prothorax is higher by 6-9 degrees C than that at the tip of the abdomen, and this in actively flying hornets outside the nest (workers, males or queens) as well as in hornets inside the nest that attend to the brood in the combs. On viewing the region from the outside, one discerns a canal or rather a fissure in the cuticle, which commences at the center of the dorsal surface of the prothorax and extends till the mesothorax. Thus the length of this canal or fissure is approximately 5-7 mm and it is seen to contain numerous thin hairs whose shape varies from that of the hairs alongside the structure. Beneath the cuticle in this region there are dorsoventral as well as longitudinal muscles in abundance, much the same as the musculature in the remaining thoracic segments (i.e. the meso- and metathorax), which activate the two pairs of wings. The canal-bearing segment is of course devoid of wings, and its dorsoventral muscles are attached to the cuticle, which in this region resembles a bowl harboring several layers of epithelium that boasts numerous butterfly-shaped tracheal branches. Additionally there are layers that display lymph-filled spaces and also perforated layers and depressions, and beneath all these is a lace-like layer that also coats the cuticle's hollows. Underneath the cuticle proper, there are numerous large mitochondria and tracheae, which occupy a considerable part of the cuticular epithelium surface. These abundant mitochondria are, most probably, the main element of heat production in the thermogenic center.     

Ni–C powder synthesis by a submerged pulsed arc in breakdown mode

Powders of Ni–C nanoparticles were synthesized using a pulsed arc between Ni electrodes submerged in pure ethanol. The arc was ignited by inter-electrode breakdown. The ethanol was arc treated for 5 min with 1 μs duration pulses, at a repetition rate of 1 kHz. The pulse energy was in a range of 0.01–0.05 J. Powder samples were obtained by extracting liquid from the treatment vessel after a pre-determined sedimentation time, or by allowing the liquid to evaporate from the vessel, and collecting the residue. The samples were examined by HRSEM, EDX and XRD.It was found that a powder of Ni–C nanoparticles was produced. The powder consisted of carbon particles and nickel–carbon alloy particles. The latter were also coated by carbon. The carbon concentration in the Ni alloy was approximately triple of the maximum equilibrium solid solubility of carbon in nickel. The production rate of carbon was greater than the erosion rate of the Ni electrodes by factors of 2–6. The ratio of carbon production rate to electrode erosion rate decreased with the discharge energy. The size distribution of the produced particles was narrow. No particles with diameter more than 0.7 μm were observed.     

Marital relations among former prisoners of war: Contribution of posttraumatic stress disorder, aggression, and sexual satisfaction.

In this study, the authors examined the marital adjustment, spousal aggression, and sexual satisfaction of prisoners of war (POWs) 3 decades after their release. More specifically, the authors examined the extent to which impaired marital relations among former POWs are an outcome of their captivity or of the posttraumatic stress disorder (PTSD) that some of them developed. The authors compared 25 former POWs with PTSD, 85 former POWs without PTSD, and 104 control veterans. The findings reveal that the marital problems of former POWs are more related to PTSD than to their captivity. PTSD is related to decreased marital satisfaction, increased verbal aggression, and heightened sexual dissatisfaction among former POWs. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Attributional style and combat-related posttraumatic stress disorder.

This study examined the relations of attributions for good and bad events on the one hand and combat-related posttraumatic stress disorder (PTSD) on the other. The sample consisted of 262 Israeli soldiers who suffered a combat stress reaction episode during the 1982 Lebanon War and were followed 2 and 3 years after their participation in combat. Cross-sectional analyses revealed significant relations between attributions and PTSD at the two points of assessment. Changes in PTSD from Time 1 to Time 2 were also associated with changes in attribution. Theoretical and clinical implications of the findings are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Stress reaction of school-age children to the bombardment by SCUD missiles.

Stress reactions of 5th-, 7th-, and 10th-grade children (N?=?492) exposed to missile attacks during the Persian Gulf War were examined a month after the war by a questionnaire that assessed level of exposure to trauma and psychological symptoms. Higher stress responses were obtained in areas hit and were influenced by proximity to sites or individuals involved in actual damage. Gender, age, and region interacted such that 5th-grade boys reported the highest stress reactions regardless of region, whereas 5th-grade girls reported the highest stress responses only in regions hit. Gender, age, and objective and subjective stress correctly identified 75% of the children as potential clinical or nonclinical candidates. The possible mediating coping responses and applications for high-risk groups are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)