Cigarette smoking, serum lipids, folate, and vitamin B12 in lung cancer

The purpose of our study was to evaluate the effects of cigarette smoking and serum lipids, folate, and vitamin B12 on the development of lung cancer in the Turkish population. The study group consisted of patients with histologically proven lung cancer and the control group comprised healthy smokers being followed in our smoking cessation outpatient department. Smoking history was obtained from all subjects and serum total cholesterol, HDL cholesterol, triglycerides, vitamin B12, and folate levels were measured. Pack/years of cigarettes smoked were significantly higher in the subjects with lung cancer than in the control group (p < 0.01). Serum total cholesterol, HDL cholesterol, triglyceride, serum folate, and vitamin B12 levels were within normal limits in both groups (p < 0.05), but serum vitamin B12 levels were statistically significantly higher (p < 0.01) in the cancer group than in the controls. In our study, we did not observe low levels of serum cholesterol, vitamin B12, or folate in the lung cancer patients.     

Using the analytic network process (ANP) in a SWOT analysis - A case study for a textile firm

Strengths, Weaknesses, Opportunities and Threats (SWOT) analysis does not provide an analytical means to determine the importance of the identified factors or the ability to assess decision alternatives according to these factors. Although the analysis successfully pinpoints the factors, individual factors are usually described briefly and very generally. For this reason, SWOT analysis possesses deficiencies in the measurement and evaluation steps. Although the analytic hierarchy process (AHP) technique removes these deficiencies, it does not allow for measurement of the possible dependencies among the factors. The AHP method assumes that the factors presented in the hierarchical structure are independent; however, this assumption may be inappropriate in light of certain internal and external environmental effects. Therefore, it is necessary to employ a form of SWOT analysis that measures and takes into account the possible dependency among the factors. This paper demonstrates a process for quantitative SWOT analysis that can be performed even when there is dependence among strategic factors. The proposed algorithm uses the analytic network process (ANP), which allows measurement of the dependency among the strategic factors, as well as AHP, which is based on the independence between the factors. Dependency among the SWOT factors is observed to effect the strategic and sub-factor weights, as well as to change the strategy priorities.     

Medical image segmentation with transform and moment based features and incremental supervised neural network

In this study, a novel incremental supervised neural network (ISNN) is proposed for the segmentation of medical images. Performance of the ISNN is investigated for tissue segmentation in medical images obtained from various imaging modalities. Two feature extraction methods based on transform and moments are comparatively investigated to segment the tissues in medical images. Two-dimensional (2D) continuous wavelet transform (CWT) and the moments of the gray-level histogram (MGH) are computed in order to form the feature vectors of ultrasound (US) bladder and phantom images, X-ray computerized tomography (CT) and magnetic resonance (MR) head images. In the 2D-CWT method, feature vectors are formed by the intensity of one pixel of each wavelet-plane of different energy bands. The MGH represents the tissues within the sub-windows by using the spatial variation of image intensities. In this study, the ISNN and Grow and Learn (GAL) network are employed for the segmentation task. It is observed that the ISNN has significantly eliminated the disadvantages of the GAL network in the segmentation of the medical images.     

Lipase catalyzed synthesis of polycaprolactone and clay-based nanohybrids

This study presents the use of original systems based on Candida antarctica lipase B (CALB) immobilized on montmorillonite and sepiolite nanoclays as efficient catalysts for the enzymatic polymerization of ε-caprolactone (ε-CL) and the in situ elaboration of nanohybrids.     

Inflammation in the Human Periodontium Induces Downregulation of the α1- and β1-Subunits of the sGC in Cementoclasts

Nitric oxide (NO) binds to soluble guanylyl cyclase (sGC), activates it in a reduced oxidized heme iron state, and generates cyclic Guanosine Monophosphate (cGMP), which results in vasodilatation and inhibition of osteoclast activity. In inflammation, sGC is oxidized and becomes insensitive to NO. NO- and heme-independent activation of sGC requires protein expression of the α₁- and β₁-subunits. Inflammation of the periodontium induces the resorption of cementum by cementoclasts and the resorption of the alveolar bone by osteoclasts, which can lead to tooth loss. As the presence of sGC in cementoclasts is unknown, we investigated the α₁- and β₁-subunits of sGC in cementoclasts of healthy and inflamed human periodontium using double immunostaining for CD68 and cathepsin K and compared the findings with those of osteoclasts from the same sections. In comparison to cementoclasts in the healthy periodontium, cementoclasts under inflammatory conditions showed a decreased staining intensity for both α₁- and β₁-subunits of sGC, indicating reduced protein expression of these subunits. Therefore, pharmacological activation of sGC in inflamed periodontal tissues in an NO- and heme-independent manner could be considered as a new treatment strategy to inhibit cementum resorption.     

Neural extension of experimental data to investigate using phosphogypsume in light brick production

In this study, usability of wastes produced in phosphoric acid plants in structural brick manufacture has been investigated. There are several parameters involved in using these wastes in brick production namely the rate of added waste, firing speed and firing temperature. The performance of these parameters can be measured by several criteria such as natural drying shortening, water absorption and weight loss. Therefore, so many experiments are needed to investigate the effects of these parameters on the bricks produced with these wastes. The result of a series of experiments were utilized to achieve this end. The results have shown that the industrial wastes considered improve the performance of the bricks in terms of the criteria mentioned above. However, the results have also shown that further investigations are needed to explore the effects of interim values on the performance of the bricks. To achieve that end, a neural experimental study is adopted. For this purpose, the results of the experiments conducted were used to construct an artificial neural network. The trained and tested network was then used to check the effects of 280 different combinations for each type of material mixtures mentioned. The outcome of these artificial tests have provided the optimal values for the waste addition rate, firing speed and firing temperature based on the four criteria mentioned previously.     

Anaerobic digestion of Aegean olive mill effluents with and without pretreatment

BACKGROUND: Olive oil production is an important economical activity in the Aegean region of Turkey. However, the effluents of the olive oil producing mills with their high organic loads and toxic compounds are causing serious environmental problems. The anaerobic biological treatment of olive mill wastewater (OMWW) using the treatment plants of the regional industries could be a method of choice and within the scope of this study floccular and granular sludges were investigated in batch mode for their success in the treatment of OMWW while producing biogas. The major limitation of this treatment is the inhibition of methanogenic bacteria by the phenolic compounds in OMWW. Thus an integrated solution was suggested in which a pre‐treatment step (dephenolization) was also introduced before biological step. RESULTS: The effluents of 27 olive mills out of 47 were found to have total phenolics (TP) less than 3 g L^?1 and could be treated anaerobically after simple dilution. The biogas production for the untreated OMWW was higher for floccular sludge than for the granular sludge (68.5 mL and 45.7 mL respectively). Combined pre‐treatment experiments, first coagulation with polyaluminum chloride, followed by flocculation with cationic polyelectrolyte and finally Fenton's oxidation, could remove 80% of TP and 95% of the total suspended solids. CONCLUSION: OMWW having TP values less than 3 g L^?1 can be treated anaerobically using floccular sludge after simple dilution and biogas can be produced. For OMWW samples having higher TP values pre‐treatment is necessary and the pre‐treatment given in this study may be used effectively. Copyright © 2010 Society of Chemical Industry     

The temperature dependence of effective thermal conductivity of the samples of glass wool reinforced with aluminium foil

In this study, the temperature dependence of effective thermal conductivity (ETC) for samples of binary, ternary, and quadruple glass wools reinforced with aluminium foil was examined. The experiments were realized by the guarded hot plate in temperature differences of 5, 10 and 15 °C and the temperatures of 25 and 40 °C. The results revealed that in the case of reinforcing the aluminium foil, ETC increased with increasing the temperature or changing of temperature difference (5, and 15 °C). Also, an increase of additional layers decrease its' influence on low temperature. Consequently, reflectivity materials may increase or reduce ETC.     

A kinetic study on the autoxidation of sunflowerseed oil

Unhydrogenated and hydrogenated sunflowerseed oils were exposed to the autoxidation process by sunlight under atmospheric conditions. Experiments were carried out in equal-sized glass, PET (polyethylene terephthalate) polymer, and metal (covered by tin) containers. The reaction time was 30 d, and the reaction course was observed by determining weight changes and peroxide values (PV) of the oil samples at the same time within 2-d intervals. The logarithm of the PV was plotted against time, and straight lines were obtained from the 4th or 6th d. The autoxidation reaction constants were obtained for each oil in each container. When comparing the reaction constants, the unhydrogenated oils autoxidize easily, and the autoxidation reaction occurs faster in sunlight in glass than in the PET polymer container and much faster than in the darkness of the metal container.     

Effects of dough formula and baking conditions on acrylamide and hydroxymethylfurfural formation in cookies

The effects of dough formula and baking conditions on the formations of acrylamide and hydroxymethylfurfural (HMF) were studied in a cookie model system. Increasing the sugar concentration in the dough formula increased acrylamide formation during baking at 205 °C for 11 min. The effect of sugar on acrylamide formation was more pronounced for glucose than for sucrose, expectedly. Addition of citric acid into dough formula comprising sucrose increased the susceptibility of acrylamide formation, while it decreased acrylamide formation in the dough formula comprising glucose. Decreasing the pH of dough formula increased the tendency to surface browning and the formation of hydroxymethylfurfural in cookies during baking. The results suggest that a cookie with acceptable texture and colour, but having less than 150 ng/g of acrylamide, can be manufactured by lowering the baking temperature and avoiding reducing sugars in the recipe.