Cardiovascular effects produced by R-(+)-8-hydroxy-2-(di-n-propylamino) tetralin in the preoptic area of conscious rats

The effect of ancrod-induced defibrinogenation on thrombosis and bleeding time was determined in anesthetized rats. Functional plasma fibrinogen levels were reduced 42, 71, 94 and 93% by ancrod doses of 5, 10, 20 and 30 U/kg, respectively, while a 2.5 U/kg dose was without significant effect. Ancrod inhibited vena cava thrombosis induced by partial stasis of blood flow combined with mild vascular injury. Thrombus weight was decreased 85 and 93% by the 10 and 20 U/kg doses, but was unaffected at lower doses. In contrast, ancrod doses of up to 30 U/kg did not significantly decrease carotid artery thrombi formed in response to oxidative transmural vessel injury. Ancrod caused a dose-dependent increase in bleeding time measured by puncturing small mesenteric arteries with a hypodermic needle. The bleeding time increase was approximately 38% in response to the 2.5 and 5 U/kg doses, and 182% in response to the 10 U/kg dose. These studies demonstrate that ancrod-induced reductions in plasma fibrinogen more effectively inhibit venous compared to arterial thrombosis, although these activities require doses that also increase bleeding time in small arteries.     

Retroclival epidural hematoma secondary to decompressive craniectomy in cerebellar infarction: MR demonstration

A simple and rapid methodology for the preparation of single-cell suspension from animal tissues is described. It uses a device called a "tissue press" to mince the tissue into small pieces of desired sizes which are then dissociated into single cells using a pipette. The device is inexpensive and the method economizes time and labor. An example of its use in DNA double-strand breaks study, using microgel electrophoresis, is described.     

Wıreless Communıcatıons Beyond 5 g: Teraherzwaves,Nano-Communıcatıons and the Internet of Bıo-Nano-Thıngs

Two promising technologies cosidered for the Beyond 5G networks are the terahertz and nano-technologies. Besides other possible application areas they hold the commitment to numerous new nano-scale solutions in the biomedical field. Nano-technology, as the name implies, examines the construction and design of nano-sized materials. These two interconnected emerging technologies have the potential to find application in quite many areas, one of the most importan being healthcare. This overview paper discusses the specifics of these technologies, their most important characteristics and introduces some of the trends for their application in the healthcare sector. In the first section terahertz frequency radio waves and their specific properties depending on the surrounding environment are discussed, followed by an introduction to nano-scale communications. Terahertz waves mandate the use of nano-scale antennas, which in turn brings us to the concept of nano-scale nodes. Nano-scale nodes are units that can perform the most basic functions of nano-machines and inter-nano-machine communications, which allow distributed nano-machines to perform more complex functions. Beyond 5G the development of these nano-communications is expected to lead to the emergence of new complex network systems. In the second part of this paper the paradigms of the Internet of Nano Things, molecular commnications and the Internet of Bio-Nano Things are discussed followed by details on their integration in healthcare related applications. The main goal of the article is to provide an introduction to these intriguing issues discussing advanced nano-technology enablers for Beyond 5G networks such as terahertz and molecular communications, nano-communications between nano-machines and the Internet of Bio-Nano-Things in light of health related applications.

     

Removal of power line interference in signal-averagedelectrocardiography systems

A method for line interference reduction to be used in signal-averaged electrocardiography (SAECG) systems is proposed and its performance is analyzed. This new method is an adaptation of a previously reported technique for removal of line interference from conventional electrocardiograms. It involves the recording of a line reference signal simultaneous with the lead signals, so that a shifted and sealed version of it can be used to subtract line interference from the leads. It is shown that this line interference subtraction method can reduce line interference effectively and without introducing any additional noise into the ECG signal. It is also shown that Late Potential diagnostic decisions are not altered when this filter is applied. It is recommended that this technique be used in SAECG when line interference is unavoidable     

CONTROLS ON FRACTURE FLOW POTENTIAL IN A TIGHT CARBONATE RESERVOIR: SAYINDERE FORMATION (CAMPANIAN), WEST ADIYAMAN BASIN,SE TURKEY

Identifying controls on the permeability of fluid‐conductive fractures is critical in tight reservoirs, but this is challenging in tectonically complex regions such as foothills belts where there may have been multiple stages of deformation and fracturing. Fracture permeability depends on fracture aperture and connectivity, both of which are affected by tectonism and cementation. Among the many factors that control the cementation history, oil charging may play an important role. Important challenges in studies of fractured reservoirs in tectonically complex regions include determining the timing (and intensity) of fracturing events relative to that of the oil charge, verifying the presence of matrix storage, and establishing the fracture cementation history. This paper reports on a comparative fracture study of four small‐scale oilfields in the west Ad?yaman Basin, located within the foothills belt of the Tauride suture zone in SE Turkey. Here the tight reservoir carbonates of the Say?ndere Formation (Campanian) were subjected to repeated phases of structural deformation. Major deformation phases took place in Campanian and Maastrichtian times, before oil charging into the reservoir began in the Eocene; and in the Late Eocene – Oligocene and Late Miocene, after the oil charge. Fractures that were generated before oil emplacement appear to have been cemented or partially cemented by calcite as indicated by cross‐cutting cemented fractures on borehole images. Partially‐cemented fractures in cores are oil‐stained with cement‐lined walls, suggesting cementation began before oil emplacement but was not completed. Image logs and cores also show the presence of clean, open fractures with no cement present on the walls. These open fractures cut across the cemented or partially‐cemented fractures, and are in general related to Late Miocene compressional folding. Open fracture density is correlated to Late Miocene fold curvature and asymmetry in the four oilfields studied. Of these fields, the ?ambayat structure is the tightest and most asymmetric anticline and hence has the maximum open fracture density; this field also has the highest oil potential. Although the available data is not sufficient to evaluate the effects of oil charging on fracture cementation definitively, the observations are consistent with a model that oil charge into the fractured Say?ndere Formation carbonates inhibited or slowed calcite cementation. Hence fracturing of a carbonate reservoir after oil emplacement may significantly enhance the fracture permeability, and may even render a tight reservoir prospective.     

Measurement invariance of the Gifted Rating Scales—School Form across five cultural groups.

This study examined measurement invariance of the Gifted Rating Scales—School Form (GRS–S) across the United States, Puerto Rico, China, South Korea, and Turkey, using multigroup confirmatory factor analysis. A total of 1,817 students were rated by 287 teachers using either translated versions of GRS–S or the original English GRS–S. Results indicate a similar factor structure for the GRS–S across the five locations; six factors with each of the 72 items equivalently loaded to the same latent variable across groups. The metric invariance test and the factor variance and covariance invariance tests reveal that the patterns of factor loadings and the factor variances and covariances are invariant across the five groups. Moreover, the scalar invariance test indicates that item means are equivalent across the groups. These results suggest that the GRS–S has intercultural utility and can be similarly interpreted. Implications and limitations of the present research for gifted identification are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Double Carbonylation Reactions of Enynols and Thiols to Form Thioester Substituted 6‐Membered Ring Lactones

The double carbonylation reaction of enynols with thiols affords functionalized 6‐membered ring lactones. Two kinds of 6‐membered ring lactones were obtained by the use of different palladium complexes with added phosphine ligands.