An Eco-Friendly Approach to the Control of Pathogenic Microbes and Anopheles stephensi Malarial Vector Using Magnesium Oxide Nanoparticles (Mg-NPs) Fabricated by Penicillium chrysogenum

The discovery of eco-friendly, rapid, and cost-effective compounds to control diseases caused by microbes and insects are the main challenges. Herein, the magnesium oxide nanoparticles (MgO-NPs) are successfully fabricated by harnessing the metabolites secreted by Penicillium chrysogenum. The fabricated MgO-NPs were characterized using UV-Vis, XRD, TEM, DLS, EDX, FT-IR, and XPS analyses. Data showed the successful formation of crystallographic, spherical, well-dispersed MgO-NPs with sizes of 7–40 nm at a maximum wavelength of 250 nm. The EDX analysis confirms the presence of Mg and O ions as the main components with weight percentages of 13.62% and 7.76%, respectively. The activity of MgO-NPs as an antimicrobial agent was investigated against pathogens Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans, and exhibited zone of inhibitions of 12.0 ± 0.0, 12.7 ± 0.9, 23.3 ± 0.8, 17.7 ± 1.6, and 14.7 ± 0.6 mm respectively, at 200 µg mL⁻¹. The activity is decreased by decreasing the MgO-NPs concentration. The biogenic MgO-NPs exhibit high efficacy against different larvae instar and pupa of Anopheles stephensi, with LC50 values of 12.5–15.5 ppm for I–IV larvae instar and 16.5 ppm for the pupa. Additionally, 5 mg/cm² of MgO-NPs showed the highest protection percentages against adults of Anopheles stephensi, with values of 100% for 150 min and 67.6% ± 1.4% for 210 min.     

An enhanced LBP-based technique with various size of sliding window approach for handwritten Arabic digit recognition

Many variations of local binary pattern (LBP) were proposed to enhance its performance, including uniform local binary pattern (ULBP), center-symmetric local binary patterns (CS-LBP), center symmetric local ternary patterns (CS-LTP), center symmetric local multilevel pattern (CS-LMP), etc. In this paper, the accuracies of LBP technique and its variations are enhanced using four different sizes of a sliding window approach. This approach is used for investigating whether the features extracted by LBP are significant enough or its versions are needed as well. Five LBP-based techniques have been used including LBP, CS-LBP, CS-LTP, CS-LMP, and U2LBP. They have been applied to an Arabic digit image dataset called MAHDBase. Support vector machine (SVM) and random forests are utilized as classifiers. The experimental results show that the obtained accuracies have been improved by 19.56%, 21.43%, 5.63%, 6.51% and 5.62% for CS-LBP, CS-LMP, U2LBP, CS-LTP, and LBP, respectively, when the sliding window approach has been applied and SVM with linear kernel has been used as a classifier. Moreover, the results show that there is no need to use LBP variations to enhance the accuracy if the sliding window is applied because the highest accuracy has been acquired using LBP. At the end, the accuracy of proposed systems has been compared against other state-of-the-art LBP-based techniques showing the significance of the proposed systems.

     

Developing an Interactive Spatial Multi-Attribute Decision Support System for Assessing Water Resources Allocation Scenarios

Water Resources Management - In water resource management, assessing water resource allocation scenarios (WRASs) is an important multi-attribute decision making (MADM) problem. It involves...     

Characterization of minocycline loaded chitosan/polyethylene glycol/glycerol blend films as antibacterial wound dressings

Wound care has been a challenging subject for medical teams and researchers. Bacterial infections are one of the most serious complications in injured skins that often affect healing process. Antibacterial wound dressings can be used to facilitate wound healing process. The purpose of this study is to fabricate chitosan (Chito)/polyethylene glycol (PEG) antibacterial wound dressing doped with minocycline, and to evaluate the influence of composition ratio on the blending properties of the films. To improve the mechanical properties of these films, we examined various amounts of glycerol as a plasticizer. Moreover, we investigated morphological and mechanical aspects, water uptake, degradation, water vapor transmission and wettability properties of the films prepared with various ratios of Chito/PEG/Gly. Assessment of mechanical properties revealed that film containing 80:20 ratio Chito/PEG with 40 PHR Gly content exhibits the highest ultimate tensile strength and elongation at break (9.74 MPa and 45.73% respectively). Furthermore, results demonstrated that upon increasing PEG and Gly contents, degradability and hydrophilicity of the films increased whereas water uptake decreased. Water vapor transmission rate of the films was close to the range of 530–1200 g/m²d, indicating that the as formed films are possible candidates for dressing low exudate wounds or burns. Minocycline loaded films exhibited a biphasic drug release profile and it was more effective on gram-positive bacteria than on gram-negative bacteria. The polymeric film with the highest amount of loaded drug (2%) exhibited insignificant cytotoxicity (88%) against normal fibroblast cell line.     

Predictive control for voltage collapse avoidance using a modified discrete multi-valued PSO algorithm

Voltage stability is one of the most challenging concerns that power utilities are confronted with, and this paper proposes a voltage control scheme based on Model Predictive Control (MPC) to overcome this kind of instability. Voltage instability has a close relation with the adequacy of reactive power and the response of Under Load Tap Changers (ULTCs) to the voltage drop after the occurrence of a contingency. Therefore, the proposed method utilizes reactive power injection and tap changing to avoid voltage collapse. Considering discrete nature of the changes in the tap ratio and also in the reactive power injected by capacitor banks, the search area for the optimizer of MPC will be an integer area; consequently, a modified discrete multi-valued Particle Swarm Optimization (PSO) is considered to perform this optimization. Simulation results of applying the proposed control scheme to a 4-bus system confirm its capability to prevent voltage collapse.     

Supporting multiple perspectives in feature-based configuration

Feature diagrams have become commonplace in software product line engineering as a means to document variability early in the life cycle. Over the years, their application has also been extended to assist stakeholders in the configuration of software products. However, existing feature-based configuration techniques offer little support for tailoring configuration views to the profiles of the various stakeholders. In this paper, we propose a lightweight, yet formal and flexible, mechanism to leverage multidimensional separation of concerns in feature-based configuration. We propose a technique to specify concerns in feature diagrams and to generate automatically concern-specific configuration views. Three alternative visualisations are proposed. Our contributions are motivated and illustrated through excerpts from a real web-based meeting management application which was also used for a preliminary evaluation. We also report on the progress made in the development of a tool supporting multi-view feature-based configuration.     

Parallel Lagrange interpolation on <Emphasis Type="Italic">k</Emphasis>-ary <Emphasis Type="Italic">n</Emphasis>-cubes with maximum channel utilization

This paper proposes an efficient parallel algorithm for computing Lagrange interpolation on k-ary n-cube networks. This is done using the fact that a k-ary n-cube can be decomposed into n link-disjoint Hamiltonian cycles. Using these n link-disjoint cycles, we interpolate Lagrange polynomial using full bandwidth of the employed network. Communication in the main phase of the algorithm is based on an all-to-all broadcast algorithm on the n link-disjoint Hamiltonian cycles exploiting all network channels, and thus, resulting in high-efficiency in using network resources. A performance evaluation of the proposed algorithm reveals an optimum speedup for a typical range of system parameters used in current state-of-the-art implementations.

Low voltage second-order alpha function synapse

This paper introduces a Transimpedance Amplifier (TIA) design capable of producing an incremental input resistance in the ohmic range, for input signals in the microampere range, such as are encountered in the design of instrumentation for electrochemical ampero-metric sensors, optical-sensing and current-mode circuits. This low input-resistance is achieved using an input stage incorporating negative feedback. In a Cadence simulation of an exemplary design using a 180 nm CMOS process and operating with?±?1.8 V supply rails, the input resistance is 1.05 ohms and the power dissipation is 93.6 µW. The bandwidth, for a gain of 100 dBohm, exceeded 9 MHz. For a 1µA, 1 MHz sinusoidal input signal the Total Harmonic Distortion, with this gain, is less than 1%. The input referred noise current with zero photodiode capacitance is 2.09 pA/√Hz and with a photodiode capacitance of 2pF is 8.52 pA/√Hz. Graphical data is presented to show the effect of a photodiode capacitance varying from 0.5 to 2 pF, when the TIA is used in optical sensing. In summary, the required very low input resistance, at a low input current level (µA) is achieved and furthermore a Table is included comparing the characteristics and a widely used Figure of Merit (FOM) for the proposed TIA and similar published low-power TIAs. It is apparent from the Table that the FOM of the proposed TIA is better than the FOMs of the other TIAs mentioned.

     

Discrete modeling of sand–tire mixture considering grain-scale deformability

Mixing sand or soil with small pieces of tire is common practice in civil engineering applications. Although the properties of the soil are changed, it is environmentally friendly and sometimes economical. Nevertheless, the mechanical behavior of such mixtures is still not fully understood and more numerical investigations are required. This paper presents a novel approach for the modeling of sand–tire mixtures based on the discrete element method. The sand grains are represented by rigid agglomerates whereas the tire grains are represented by deformable agglomerates. The approach considers both grain shape and deformability. The micromechanical parameters of the contact law are calibrated based on experimental results from the literature. The effects of tire content and confining pressure on the stress–strain response are investigated in detail by performing numerical triaxial compression tests. The main results indicate that both strength and stiffness of the samples decrease with increasing tire content. A tire contact of 40% is identified as the boundary between rubber-like and sand-like behavior.     

UML-CI: A reference model for profiling critical infrastructure systems

The study of critical infrastructure systems organization and behavior has drawn great attention in the recent years. This is in part due to their great influence on the ordinary life of every citizen. In this paper, we study critical infrastructures’ characteristics and propose a reference model based on the Unified Modeling Language (UML). This reference model attempts to provide suitable means for the task of modeling an infrastructure system through offering five major metamodels. We introduce each of these metamodels and explain how it is possible to integrate them into a unique representation to characterize various aspects of an infrastructure system. Based on the metamodels of UML-CI, infrastructure system knowledge bases can be built to aid the process of infrastructure system modeling, profiling, and management.