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排序方式: 共有192条查询结果,搜索用时 15 毫秒
1.
Jon T. Carter Paul E. Krajewski Ravi Verma 《JOM Journal of the Minerals, Metals and Materials Society》2008,60(11):77-81
The hot blow forming of magnesium sheet offers significant opportunity for forming complex, lightweight parts for automotive
applications. This paper characterizes the elevated-temperature formability of AZ31 magnesium sheet materials and the effect
of processing conditions on the performance of these materials. In addition, magnesium sheet application development at General
Motors Corporation is reviewed. 相似文献
2.
3.
Apoptosis in the failing human heart 总被引:1,自引:0,他引:1
G Olivetti R Abbi F Quaini J Kajstura W Cheng JA Nitahara E Quaini C Di Loreto CA Beltrami S Krajewski JC Reed P Anversa 《Canadian Metallurgical Quarterly》1997,336(16):1131-1141
BACKGROUND: Loss of myocytes is an important mechanism in the development of cardiac failure of either ischemic or nonischemic origin. However, whether programmed cell death (apoptosis) is implicated in the terminal stages of heart failure is not known. We therefore studied the magnitude of myocyte apoptosis in patients with intractable congestive heart failure. METHODS: Myocardial samples were obtained from the hearts of 36 patients who underwent cardiac transplantation and from the hearts of 3 patients who died soon after myocardial infarction. Samples from 11 normal hearts were used as controls. Apoptosis was evaluated histochemically, biochemically, and by a combination of histochemical analysis and confocal microscopy. The expression of two proto-oncogenes that influence apoptosis, BCL2 and BAX, was also determined. RESULTS: Heart failure was characterized morphologically by a 232-fold increase in myocyte apoptosis and biochemically by DNA laddering (an indicator of apoptosis). The histochemical demonstration of DNA-strand breaks in myocyte nuclei was coupled with the documentation of chromatin condensation and fragmentation by confocal microscopy. All these findings reflect apoptosis of myocytes. The percentage of myocytes labeled with BCL2 (which protects cells against apoptosis) was 1.8 times as high in the hearts of patients with cardiac failure as in the normal hearts, whereas labeling with BAX (which promotes apoptosis) remained constant. The near doubling of the expression of BCL2 in the cardiac tissue of patients with heart failure was confirmed by Western blotting. CONCLUSIONS: Programmed death of myocytes occurs in the decompensated human heart in spite of the enhanced expression of BCL2; this phenomenon may contribute to the progression of cardiac dysfunction. 相似文献
4.
Optical studies of LiKSO4 crystals were performed in polarized 11yh.t within the temperature range from 300 up to 1000 K. The observations confirmed the existence of two phase transitions at about 700 and 940 K respectively. The high-temperature phase between 700 and 940 K was found to be ferroelastic. 相似文献
5.
This study examined whether gender and work stressor context interacted to affect reports of occupational coping strategies. Participants (N=113) were asked to indicate how they would cope with both self-focused (i.e., solitary) and interpersonal (i.e., group) work overload contexts by providing responses to the Cybernetic Coping Scale (J. Edwards & A. J. Baglioni, 1993). Consistent with the hypothesized interaction, male and female participants evidenced similar coping strategies in the self-focused work overload context, whereas female participants showed significantly higher use of coping (T2=.08, p 相似文献
6.
7.
Dipl.-Ing. Dr. mont. Pawel Krajewski Christian Bernhard Roman Krobath Thomas Schaden Sergiu Ilie 《BHM Berg- und Hüttenm?nnische Monatshefte》2014,159(7):304-305
Continuous casting of steel free of surface cracks is still one of the major quality challenges in the whole steel production. The key roles for the phenomenon of surface cracking are played by the critical strain and the temperature-dependent material’s phenomena. The new In-Situ Characterization Bending (IMC-B) method will enable the investigation of the critical strains with respect to the cracking under the main continuous casting boundaries. This publication presents potential and interesting results of the IMC-B experiment. 相似文献
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9.
M. Godlewski E. Guziewicz T. Krajewski ?. Wachnicki A. Wachnicka K. Kopalko B. Dalati 《Thin solid films》2009,518(4):1145-272
We demonstrate possibility of a control (by selection of zinc precursors and variation of a growth temperature) of electrical properties of ZnO films grown by Atomic Layer Deposition (ALD). ZnO films grown by ALD are used in test photovoltaic devices (solar cells) as transparent conductive oxides for upper, transparent layer in inorganic and organic solar cells, and as n-type partners of p-type CdTe. 相似文献
10.
Estrogen withdrawal-induced human breast cancer tumour regression in nude mice is prevented by Bcl-2
MA Pratt S Krajewski M Menard M Krajewska H Macleod JC Reed 《Canadian Metallurgical Quarterly》1998,440(3):403-408
The purpose of this study was to assess the safety and efficacy of percutaneous transluminal cerebral balloon angioplasty (PTCBA) of extra- and intra-cranial arteries by investigating procedural outcome. Eighty haemodynamically significant extra- and intra-cranial lesions (% diameter stenosis > 70) in 74 clinically symptomatic patients were treated by elective and initial PTCBA between March 1991 and February 1996 and thereafter followed. Death, stroke, surgery, or repeated angioplasty of restenosis or new lesions were regarded as cerebral events after the initial PTCBA. The procedural and clinical success rates were 81 % (65 of 80) and 81 % (60 of 74), respectively. Progressively ischaemic symptoms disappeared completely after clinically successful dilatation. Angiographic restenosis rate at 3 months was 22 %(14 of 65). By life-table method, the death/stroke risk was 16 %, and any cerebral event risk was 49 % at 2 years following PTCBA, respectively. The most common of first cerebral events presented was repeated angioplasty of restenosis. In conclusion, PTCBA has great efficacy in decreasing recurrent neurological symptoms and produces a favourable short-term outcome, whereas restenosis limits long-term benefit. 相似文献