Combination of vegetable soup and glucan demonstrates synergistic effects on macrophage-mediated immune responses

Vegetable soup (VS), a plant-based functional food, has been used as a traditional folk medicine and is attracting attention for its ability to enhance the immune response. β-Glucan, a well-established and effective immunomodulator, has synergistic effects when used in combination with some bioactive compounds. In the present study, we aimed to evaluate the synergistic immunomodulatory effects of the combination of VS and β-glucan on macrophage-mediated immune responses. β-Glucan was demonstrated to synergistically enhance the VS-stimulated immune response, including the production of interleukin-6, tumor necrosis factor-α, and nitric oxide, mainly through the mitogen-activated protein kinase pathway in macrophages. In addition, this combination has the potential for further development in functional foods with immune-enhancing activity.Supplementary InformationThe online version contains supplementary material available at 10.1007/s10068-021-00888-x.     

The concept of directional binding energy and analysis of the phenomena involving surface and grain boundary: Part I Theory

The concept of directional binding energy (DBE) is proposed to describe the binding energy of the crystal and the ideal direction of the antiaction force against the surface tension, which derives the grain-boundary energy and also energy ratio (γ_gb/γ_s). It may provide a simple and lucid way to analyse the surface energy, grain-boundary energy and energy ratio from the correlative view point. It has been found that the grain-boundary energy can be derived only from the conceptual approach of DBE, irrespective of the dislocation model, which also makes it possible to determine the energy ratio with the misorientation angle. That is, the energy ratio (γ_gb/γ_s) is proportional to the misorientation angle, 2 sin (k′θ/2) where k′ is a constant and θ is the misorientation angle. This revised version was published online in November 2006 with corrections to the Cover Date.     

Study of alinite cement hydration by impedance spectroscopy

Two types of alinite cements, Mg-alinite and Zn-alinite, were synthesized using the reagent grade chemicals. Their hydration behavior was compared with ordinary Portland cement (OPC) using impedance spectroscopy (IS) and ²⁹Si nuclear magnetic resonance (NMR) spectroscopy. The bulk resistance in the IS spectra and the intensity ratio of the hydrous (Q₁ and Q₂) to anhydrous (Q₀) phases in the NMR spectra were estimated as the extent of hydration. The results obtained from both techniques were consistent each other. Mg-alinite had a comparable hydration rate to OPC and Zn-alinite exhibited faster hydration kinetics than Mg-alinite.     

Synthesis, structure and magnetic properties of β-MnO 2 nanorods

We present synthesis, structure and magnetic properties of structurally well-ordered single-crystalline β-MnO₂ nanorods of 50–100 nm diameter and several μm length. Thorough structural characterization shows that the basic β-MnO₂ material is covered by a thin surface layer (∼2.5 nm) of α-Mn₂O₃ phase with a reduced Mn valence that adds its own magnetic signal to the total magnetization of the β-MnO₂ nanorods. The relatively complicated temperature-dependent magnetism of the nanorods can be explained in terms of a superposition of bulk magnetic properties of spatially segregated β-MnO₂ and α-Mn₂O₃ constituent phases and the soft ferromagnetism of the thin interface layer between these two phases.     

Fuel combustion test in constant volume combustion chamber with built-in adaptor

Combustion tests of pre-mixture of methane and air in constant volume combustion chamber(CVCC) have been carried out by means of flame propagation photo and gas pressure measurement,the effects of CVCC body temperature,intake pressure of pre-mixture of methane and air,equivalence ratio and location of the built-in adaptor have been investigated.The whole combustion chamber can be divided into two parts,i.e.the upper combustion chamber and the lower combustion chamber,by the built-in adaptor with through hol...     

铝合金ADC12Z高压铸造过程中铸件与铸型间界面热交换系数的研究

通过采集高压铸造过程中铸型内部温度的变化曲线,采用热传导反算法,求解了以铝合金ADC12Z为铸件材料的铸件-铸型界面换热系数,分析了该界面换热系数随铸件厚度的变化规律.计算及分析结果表明:在压铸过程中,铸件-铸型界面换热系数迅速升至最大值,随后下降,凝固结束后趋于稳定.铸件厚度增大不仅提高了换热系数,而且对换热系数的变化趋势也有很大影响.同时,不同厚度的铸件,其固相率和冷却速率的变化规律也有较大区别.     

EvoOligo: Oligonucleotide Probe Design With Multiobjective Evolutionary Algorithms

Probe design is one of the most important tasks in successful deoxyribonucleic acid microarray experiments. We propose a multiobjective evolutionary optimization method for oligonucleotide probe design based on the multiobjective nature of the probe design problem. The proposed multiobjective evolutionary approach has several distinguished features, compared with previous methods. First, the evolutionary approach can find better probe sets than existing simple filtering methods with fixed threshold values. Second, the multiobjective approach can easily incorporate the user's custom criteria or change the existing criteria. Third, our approach tries to optimize the combination of probes for the given set of genes, in contrast to other tools that independently search each gene for qualifying probes. Lastly, the multiobjective optimization method provides various sets of probe combinations, among which the user can choose, depending on the target application. The proposed method is implemented as a platform called EvoOligo and is available for service on the Web. We test the performance of EvoOligo by designing probe sets for 19 types of Human Papillomavirus and 52 genes in the Arabidopsis Calmodulin multigene family. The design results from EvoOligo are proven to be superior to those from well-known existing probe design tools, such as OligoArray and OligoWiz.     

基于动态特性的剑杆织机共轭凸轮开口机构的设计方法

重新建立了共轭凸轮开口机构的动力学模型,组成相应的弹性振动微分方程.用矩阵摄动法分析该微分方程,并设计织机的开口机构.与传统的求解方法相比,计算时间减少20%,减小综框的振动以及降低断纬频率达到65%以上.