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排序方式: 共有82条查询结果,搜索用时 15 毫秒
1.
B. R. Patterson Ph.D. C. S. Aria M.S. 《JOM Journal of the Minerals, Metals and Materials Society》1989,41(8):22-25
For metal and ceramic injection molding procedures which use wax binders in the production of powder-based parts, melt wicking is commonly employed to debind the components prior to sintering. Because debinding is often a time-consuming procedure, the influence of such process variables as powder size, part height, green density and temperature have been investigated to reduce the amount of time required for debinding by melt wicking. 相似文献
2.
Claudia Riccardi Federica DAria Filomena Anna Digilio Maria Rosaria Carillo Jussara Amato Dominga Fasano Laura De Rosa Simona Paladino Mariarosa Anna Beatrice Melone Daniela Montesarchio Concetta Giancola 《International journal of molecular sciences》2022,23(9)
A set of guanine-rich aptamers able to preferentially recognize full-length huntingtin with an expanded polyglutamine tract has been recently identified, showing high efficacy in modulating the functions of the mutated protein in a variety of cell experiments. We here report a detailed biophysical characterization of the best aptamer in the series, named MS3, proved to adopt a stable, parallel G-quadruplex structure and show high nuclease resistance in serum. Confocal microscopy experiments on HeLa and SH-SY5Y cells, as models of non-neuronal and neuronal cells, respectively, showed a rapid, dose-dependent uptake of fluorescein-labelled MS3, demonstrating its effective internalization, even in the absence of transfecting agents, with no general cytotoxicity. Then, using a well-established Drosophila melanogaster model for Huntington’s disease, which expresses the mutated form of human huntingtin, a significant improvement in the motor neuronal function in flies fed with MS3 was observed, proving the in vivo efficacy of this aptamer. 相似文献
3.
Elnaz Akbari Zolkafle Buntat Aria Enzevaee Mahsa Khoshkhooy Yazdi Mahdi Bahadoran Ali Nikoukar 《Nanoscale research letters》2014,9(1):402
Carbonaceous materials have recently received attention in electronic applications and measurement systems. In this work, we demonstrate the electrical behavior of carbon films fabricated by methane arc discharge decomposition technique. The current-voltage (I-V) characteristics of carbon films are investigated in the presence and absence of gas. The experiment reveals that the current passing through the carbon films increases when the concentration of CO2 gas is increased from 200 to 800 ppm. This phenomenon which is a result of conductance changes can be employed in sensing applications such as gas sensors. 相似文献
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Ali Najafi Aria Alasty Ramin Vatankhah Mohammad Eghtesad Farhang Daneshmand 《Asian journal of control》2017,19(6):2219-2225
Boundary stabilization of vibrating three‐dimensional Cosserat elastic solids are studied using mathematical tools, such as operator theory and semigroup techniques. The advantages of the boundary control laws for both boundary stabilization problems are investigated. The boundary stabilization problems are studied using a Lyapunov stability method and LaSalle's invariant set theorem. Numerical simulations are provided to illustrate the effectiveness and performance of the designed control scheme. 相似文献
7.
Hatef Aria 《国际可持续能源杂志》2013,32(8):516-527
We have developed an algorithm to optimise the fan flow rate by integrating DOE2 (building's energy simulation software) with MATLAB's genetic algorithm. In our developed algorithm, MATLAB can send desired values of optimisation variables for different hours to DOE2 to simulate building's energy use, and it can also receive building's energy consumption and other data from DOE2 for the optimisation. This powerful optimisation tool can be used for finding optimal solution of night-time ventilation fan flow rates and maximising energy savings. Results of optimisation are used to train a neural network to predict fan flow rates for different conditions. Night-time ventilation investigated in DOE2 considers parameters such as (1) night-time ventilation duration, (2) ventilation fan flow rate, (3) outdoor temperature, and (4) temperature difference between outdoor and indoor. Optimisation results show outdoor temperature between 10°C and 18°C and the temperature difference of more than 8°C are appropriate for night-time ventilation. 相似文献
8.
Majid Shahzad Michel ChaussumierRémy Chieragatti Catherine MabruFarhad Rezai Aria 《Journal of Materials Processing Technology》2010,210(13):1821-1826
The objective of the present work is to show the influence of machining and anodizing processes on fatigue life of alloy 7010-T7451. Two different cutting conditions were employed to obtain two different initial surface roughnesses. Degreasing, pickling and anodizing were then carried out. In the as machined condition, surface roughness is clearly effective in reducing fatigue life in this material. As the surface roughness increases fatigue life decreases and this effect is found to be more pronounced in high cycle fatigue where major portion of fatigue life is consumed in nucleating the cracks. Effects of pre-treatments, like degreasing and pickling employed prior to anodizing, on fatigue life of the given alloy were also studied. Fatigue curves showed that pickling had negative impact on fatigue life of specimens while degreasing showed no change in fatigue life. The small decrease in fatigue life of anodized specimens as compare to pickled specimens is attributed to brittle nature and micro-cracking of the coating. Scanning electron microscopic (SEM) examination revealed multi-site crack initiation for the pickled and anodized specimens. SEM examination also showed that pickling process attacked the grain boundaries and the inclusions present on the surface resulting in pits formation. These pits are of primary concern with respect to accelerated fatigue crack nucleation and subsequent anodized coating formation. 相似文献
9.
This study aims to numerically and experimentally investigate the response of a medium strength rock material under unconfined compression loading up to failure. The unconfined compressive strength (UCS) is one of the most important parameters in characterising rock material behaviour. Hence the UCS is crucial in understanding the failure mechanism of fractured rocks. An effective approach to determine the UCS and to investigate the behaviours of rock materials under unconfined compression is essential in the majority of research fields of rock mechanics. The experimental configuration for the unconfined compression test, suggested by the protocols of the ASTM standard, has some limitations which affect the accuracy in determination of the real UCS. Among several alternative configurations proposed, the Mogi's configuration seems to be the most appropriate one. Therefore, the ASTM and Mogi's configurations were used to perform the tests on a medium strength rock material, i.e. Pietra Serena sandstone. The results using two configurations were discussed in terms of the differences. The tests were also replicated in LS-DYNA using a finite element method (FEM) coupled smooth particle hydrodynamics (SPH) technique. This technique is employed in this study due to its capabilities to cope with large deformation issues related to the rocks. An advanced material model, called the Karagozian and Case Concrete (KCC) model, is implemented in the numerical simulations. The KCC model consists of three independent fixed failure surfaces and it can consider the damage accumulation based on the current state of stress among these failure surfaces. An equation-of-state (EOS) is used in conjunction with KCC material model for decoupling the volumetric and deviatoric responses. The numerical and experimental results were finally compared with the focus on the stress–strain diagram and the failure patterns. The comparison shows that the numerical results are in good agreement with the experimental results. 相似文献
10.
Aluminum control of phosphorus sorption by lake sediments 总被引:9,自引:0,他引:9
Kopácek J Borovec J Hejzlar J Ulrich KU Norton SA Amirbahman A 《Environmental science & technology》2005,39(22):8784-8789
Release of reactive (phosphate-like) phosphorus (P) from freshwater sediments represents a significant internal P source for many lakes. Hypolimnetic P release occurs under reducing conditions that cause reductive dissolution of ferric hydroxide [Fe(OH)3]. This hypolimnetic P release may be naturally low or artificially reduced by sediment with naturally high or artificially elevated concentrations of aluminum hydroxide [Al(OH)3]. We presentfield and laboratory data for a common extraction analysis of sediments from 43 lakes differing in trophic status, pH regime, climate, and P loading. The results indicate that a simple sequential extraction of sediment may be a useful predictor of sediment's ability to release P. Sequential extractions of sediment P, Al, and Fe by water (H2O), bicarbonate-dithionite (BD), and NaOH (at 25 degrees C) showed that negligible amounts of P would be released from lake sediments during hypolimnetic anoxia if either (1) the molar Al(NaOH-25):Fe(BD) ratio is > 3 or (2) the molar Al(NaOH-25):P(H2O+BD) ratio is > 25. These ratios can be used as operational targets for estimation of sediment P release potential and Al dosing of P-rich sediment to prevent hypolimnetic P release under anoxic conditions. 相似文献