Graph run-length matrices for histopathological image segmentation

The histopathological examination of tissue specimens is essential for cancer diagnosis and grading. However, this examination is subject to a considerable amount of observer variability as it mainly relies on visual interpretation of pathologists. To alleviate this problem, it is very important to develop computational quantitative tools, for which image segmentation constitutes the core step. In this paper, we introduce an effective and robust algorithm for the segmentation of histopathological tissue images. This algorithm incorporates the background knowledge of the tissue organization into segmentation. For this purpose, it quantifies spatial relations of cytological tissue components by constructing a graph and uses this graph to define new texture features for image segmentation. This new texture definition makes use of the idea of gray-level run-length matrices. However, it considers the runs of cytological components on a graph to form a matrix, instead of considering the runs of pixel intensities. Working with colon tissue images, our experiments demonstrate that the texture features extracted from "graph run-length matrices" lead to high segmentation accuracies, also providing a reasonable number of segmented regions. Compared with four other segmentation algorithms, the results show that the proposed algorithm is more effective in histopathological image segmentation.     

Cold-cavity vectorial eigenmodes of VCSELs

An analytical approximate solution of Maxwell's equations for the cold-cavity eigenmodes of cylindrical etched air-post vertical-cavity surface-emitting lasers (VCSELs) is presented. In radial and azimuthal directions, the modes correspond to the hybrid modes of cylindrical optical waveguides. A vectorial transform matrix approach is derived which takes into account coupling of bound eigenmodes in VCSEL structures. The method is illustrated for the case of noncoupled modes and the corresponding simplified transform matrix approach is used to calculate the field profiles in longitudinal direction and predict the resonance wavelengths for the VCSEL eigenmodes. Although approximate, the resulting eigenmodes may be viewed as a useful alternative to full numerical solutions, especially with regard to future more comprehensive modeling of VCSELs     

Multipath channel identification by using global optimization in ambiguity function domain

A new transform domain array signal processing technique is proposed for identification of multipath communication channels. The received array element outputs are transformed to delay-Doppler domain by using the cross-ambiguity function (CAF) for efficient exploitation of the delay-Doppler diversity of the multipath components. Clusters of multipath components can be identified by using a simple amplitude thresholding in the delay-Doppler domain. Particle swarm optimization (PSO) can be used to identify parameters of the multipath components in each cluster. The performance of the proposed PSO-CAF technique is compared with the space alternating generalized expectation maximization (SAGE) technique and with a recently proposed PSO based technique at various SNR levels. Simulation results clearly quantify the superior performance of the PSO-CAF technique over the alternative techniques at all practically significant SNR levels.     

Detection of interdependent primary systems using wideband cognitive radios

Cognitive radios (CRs) may be sharing multiple frequency bands with primary systems if the CR is a wideband or an ultra wideband (UWB) system. In that case, the CR should ensure all the coexisting primary systems in these bands are detected before it can start data transmission. In this work, we study the primary system detection performance of a wideband CR assuming that there are multiple coexisting primary systems and that these primary systems may be jointly active. Accordingly, we consider the implementation of energy detection scheme in multiple bands followed by two detection methods: (i) a maximum-a-posteriori (MAP) based detection (i.e., joint detection) that takes into account the statistics of simultaneously operating systems in independent bands and (ii) a Neyman–Pearson (NP) test based detection that optimizes the threshold values independently in each band (i.e., independent detection). For a simpler implementation of the independent detection, we show that the threshold values obtained from joint detection can be used in order to achieve the optimum NP test based independent detection results. In addition to quantifying the gain of joint detection over independent detection in terms of probabilities of false alarm and detection for practical scenarios, we also present the operation capability of CRs in terms of the fractions of time the CR can access the channel without interfering with the primary systems. The results are important for the practical implementation of multiband detection when the primary systems are known to be interdependent.     

Magnetic Field‐Induced Phase Transformation in NiMnCoIn Magnetic Shape‐Memory Alloys—A New Actuation Mechanism with Large Work Output

Magnetic shape memory alloys (MSMAs) have recently been developed into a new class of functional materials that are capable of magnetic‐field‐induced actuation, mechanical sensing, magnetic refrigeration, and energy harvesting. In the present work, the magnetic &!hyphen;field‐induced martensitic phase transformation (FIPT) in Ni₄₅Mn_36.5Co₅In_13.5 MSMA single crystals is characterized as a new actuation mechanism with potential to result in ultra‐high actuation work outputs. The effects of the applied magnetic field on the transformation temperatures, magnetization, and superelastic response are investigated. The magnetic work output of NiMnCoIn alloys is determined to be more than 1 MJ m^?3 per Tesla, which is one order of magnitude higher than that of the most well‐known MSMAs, i.e., NiMnGa alloys. In addition, the work output of NiMnCoIn alloys is orientation independent, potentially surpassing the need for single crystals, and not limited by a saturation magnetic field, as opposed to NiMnGa MSMAs. Experimental and theoretical transformation strains and magnetostress levels are determined as a function of crystal orientation. It is found that [111]‐oriented crystals can demonstrate a magnetostress level of 140 MPa T^?1 with 1.2% axial strain under compression. These field‐induced stress and strain levels are significantly higher than those from existing piezoelectric and magnetostrictive actuators. A thermodynamical framework is introduced to comprehend the magnetic energy contributions during FIPT. The present work reveals that the magnetic FIPT mechanism is promising for magnetic actuation applications and provides new opportunities for applications requiring high actuation work‐outputs with relatively large actuation frequencies. One potential issue is the requirement for relatively high critical magnetic fields and field intervals (1.5–3 T) for the onset of FIPT and for reversible FIPT, respectively.     

Evaluation of antibacterial effects of contemporary orthodontic bonding materials

Aim: The aim of this study was to evaluate the antibacterial effects of five orthodontic bonding materials commonly used in orthodontics. Materials and Methods: The antibacterial effects of five orthodontic bonding materials were evaluated against Streptococcus mutans and Streptococcus salivarius by direct contact test (DCT). Using the DCT technique, quintet specimens of Transbond XT, Blugloo, Grengloo, Light Bond, and Opal Bond were applied to the bottom and the walls of the five wells of a 96-microtiter plate with a height of 2 mm. Samples were prepared in two sets: 1-day samples and 7-day samples. Ten microliters of bacterial suspension were added to each well for direct contact with each material for 1h at 37 °C. Bacterial growth was then measured in a microplate spectrophotometer hourly at 600 nm for 24 h. Five uncoated wells with identical inoculum sizes served as positive controls. The data obtained at the end of 24 h was statistically analyzed with one-way ANOVA, and post hoc comparisons were done using Tamhane’s T2 test. Results: Blugloo generally showed better antibacterial activity than the other materials. Transbond XT did not show any antibacterial activity. There was a statistically significant difference between Transbond XT and Light Bond in the 1-day sample against S. mutans (p < 0.05). No statistically significant differences were found among the other groups (p > 0.05). Conclusion: Blugloo had the most potent antibacterial activity against S. salivarious.     

Architectural View of Flexible Aliphatic –OH Group Coordinated Hemi-Directed Pb(II)-Salen Coordination Polymer: Synthesis,Crystal Structure,Spectroscopic Insights,Supramolecular Topographies,and DFT Perspective

Journal of Inorganic and Organometallic Polymers and Materials - We serendipitously designed one novel 1D hetero-binuclear Zn(II)-Pb(II) coordination polymer, namely...