Vertical arrays of nanostructures (NSs) are emerging as promising platforms for probing and manipulating live mammalian cells. The broad range of applications requires different types of interfaces, but cell settling on NS arrays is not yet fully controlled and understood. Cells are both seen to deform completely into NS arrays and to stay suspended like tiny fakirs, which have hitherto been explained with differences in NS spacing or density. Here, a better understanding of this phenomenon is provided by using a model that takes into account the extreme membrane deformation needed for a cell to settle into a NS array. It is shown that, in addition to the NS density, cell settling depends strongly on the dimensions of the single NS, and that the settling can be predicted for a given NS array geometry. The predictive power of the model is confirmed by experiments and good agreement with cases from the literature. Furthermore, the influence of cell‐related parameters is evaluated theoretically and a generic method of tuning cell settling through surface coating is demonstrated experimentally. These findings allow a more rational design of NS arrays for the numerous exciting biological applications where the mode of cell settling is crucial. 相似文献
The present paper describes a new method for manufacturing a nanostructured porous layer of TiO2 on a conducting glass substrate for use in a dye-sensitized photoelectrochemical cell. The method involves deposition of a layer of semiconductor particles onto a conducting substrate and compression of the particle layer to form a mechanically stable, electrically conducting, and porous nanostructured film at room temperature. Photoelectrochemical characteristics and morphology of the resulting nanostructured films are presented. The potential use of the new manufacturing method in the future applications of nanostructured systems is discussed. 相似文献
We present a family of techniques for the transmission electron microscope that generate surface zone-axis patterns. These patterns display the variation of the diffracted-beam intensity as a function of the angle of the incident electrons. The conditions of the experiments are those of reflection high-energy electron diffraction at near grazing incidence. The techniques are: surface convergent-beam diffraction, a surface analogue of the Tanaka method and a modified double-rocking scheme. Experimental results are presented for diffraction from surfaces of MgO and MoS2. We anticipate that surface zone-axis patterns (surface ZAPs) will become established as an important tool for surface characterization, especially when used in conjunction with high-resolution surface imaging and surface energy loss spectroscopy; surface ZAPs may be expected to play, in surface analysis, a role analogous to that played by convergent-beam diffraction in normal transmission electron microscopy. 相似文献
In the verified architecture microprocessor (VAMP) project we have designed, functionally verified, and synthesized a processor
with full DLX instruction set, delayed branch, Tomasulo scheduler, maskable nested precise interrupts, pipelined fully IEEE
compatible dual precision floating point unit with variable latency, and separate instruction and data caches. The verification
has been carried out in the theorem proving system PVS. The processor has been implemented on a Xilinx FPGA.
A shorter version of this article with the title “Instantiating uninterpreted functional units and memory system: functional
verification of the VAMP” appeared in [8]. The work reported here was done while all the authors were with Saarland University. 相似文献
A study was made of the appraisers' effect on the estimation of metabolic rate with the Edholm scale and a table of the ISO 7243 heat stress standard. The appraisers, five experienced and five inexperienced persons, estimated the metabolic rate of three different work tasks from videotapes. Analysis of variance indicated significant ( [Formula: see text] ) differences in the appraisers' recordings of the activities. The appraisers were grouped according to the similarity of the estimated values they gave. The groups thus contained both experienced and inexperienced appraisers, and it was not possible to classify the appraisers into experienced and inexperienced groups according to their earlier experience. The metabolic rates according to the Edholm scale were higher than according to the ISO 7243 table. The differences in metabolic rates given by the individual observers varied from 38 to 118 W/m(2). The variations in the estimation of metabolic rates were greater when the Edholm scale was used. This variation caused considerable variation also in the predicted mean vote, PMV index. It is recommended that the appraisers be selected carefully, because it is not possible to know whether a randomly selected appraiser is an 'average' or an 'extreme' appraiser without a test. Before conducting extensive field surveys where several appraisers estimate the metabolic rates, it would be useful to arrange training in order to calibrate the levels of the Edholm scale as well as ISO method among the appraisers because training clearly unified the estimation. 相似文献
The Dokan Reservoir dam is a concrete cylindrical arch with gravity abutments, located on the Lesser Zab River about 60 km from the city of Sulaimani in north‐eastern Iraq. A bathymetric survey was conducted in November 2014 for a period of 10 days, using an echo sounder of 200‐kHz single beam. The survey results indicated an annual average sediment deposition of 3.8 million m3. Thirty‐two sediment samples were collected from the reservoir bed. The ratio of gravel, sand, silt and clay was 15:14:48:23, respectively. The reservoir bed is covered mainly with silt. The sediments are composed of silty clay (77.6%), silty sandy clay (10%), sandy gravely silty clay (1.2%) and gravely sandy silty clay (1%). 相似文献
Catalytic combustion, as an alternative to conventional thermal combustion, has received considerable attention during the past decade. Research efforts have been promoted by the need to meet governmental demands concerning pollution and the wish to use energy sources more efficiently. The two main advantages offered by catalytic combustors over flame combustors apply to these goals:
Catalytic combustion can be carried out over a wide range of fuel concentrations in air and at low temperatures.
These low temperatures result in attaining NO, emission levels substantially lower than possible with conventional combustors.
This work addresses the reduction of NOx by H2 under O2-rich conditions using Al2O3/SiO2-supported Pt catalysts with different loads of WOx promotor. The samples were thoroughly characterised by N2 physisorption, temperature-programmed desorption of CO, scanning electron microscopy, X-ray diffraction, laser raman spectroscopy, X-ray photoelectron spectroscopy and diffuse reflectance infrared fourier transform spectroscopy with probe molecule CO. The catalytic studies of the samples without WOx showed pronounced NOx conversion below 200 °C, whereas highest efficiency was related to small Pt particles. The introduction of WOx provided increasing deNOx activity as well as N2 selectivity. This promoting effect was referred to an additional reaction path at the Pt-WOx/Al2O3/SiO2 interface, whereas an electronic activation of Pt by strong metal support interaction was excluded.