MICROSCOPIC SPREADING CHARACTERISTICS OF NONPOLAR PERFLUOROPOLYETHER FILMS

The surface diffusion characteristics of nonpolar perfluoropolyether (PFPE) Z on carbon surfaces are investigated in two regimes, submonolayer and multilayer, for nano-thin films. For the submonolayer regime, the two-dimensional, cubic van der Waals equation of state is applied to determine the dependence of the surface diffusion coefficient on the film thickness, as experimental surface diffusion coefficients increase with increasing film thickness. For the multilayer regime, a conventional fluid mechanics analysis with position dependent viscosity and a van der Waals disjoining pressure gradient is applied to investigate the surface diffusion characteristics. The present theoretical analysis qualitatively agrees with the experimental results.     

抗病毒类化合物结构与离解速率的关系

为了解决如何筛选出更加有效的抗病毒类化合物的问题,研究了离解速率(k_(off))与抗病毒类药物结构的关系,理论依据是k_(off)常用于评价药物在人体开放性系统中的活性.首先,应用分子描述符软件计算出每个抗病毒类化合物的分子描述符,并使用多元逐步回归分析法、偏最小二乘法和遗传算法3种方法对描述符进行筛选.然后,分别采用支持向量机和BP神经网络方法建立抗病毒类化合物的k_(off)的预测模型,并用测试集对模型进行了验证.结果表明:筛选出了具有良好预测能力的描述符,建立的2个预测模型经验证均合理,对未来抗病毒类药物的研制具有指导意义.     

直流式换热器壳侧流阻特性分析

直流式换热器是动力和化工行业关键设备之一.本文基于小型直流式换热器热工水力试验结果,拟合壳侧单组支撑板区域压损和雷诺数函数关系,并通过试验数据分析扩大到表征壳侧沿程压损;通过对比试验数据,发现修正后Rehme棒束通道模型在系统和一维分析计算中更准确;CFD仿真计算结果在试验数据误差带内,且详细准确的支撑板间速度和压力分布能为换热器安全性和热工分析等提供更准确的理论依据.     

小机车新型试验电源自适应模糊PID控制系统仿真研究

针对小机车传统试验电源系统存在的电压稳定性能差、响应速度慢的问题,提出了一种自适应模糊PID控制的小机车新型试验电源系统。对自适应模糊PID控制器的设计和建模,以及仿真的效果进行了详细的阐述,并进行了系统的鲁棒性分析。同时还将自适应模糊PID控制和传统PID控制进行了对比研究,证明了自适应模糊PID控制的小机车试验电源系统有电压稳定性能好、响应速度快的良好电气特性。     

兰炭气全低变制氢工艺的工业应用

针对兰炭气有效成分低、杂质多、有毒物质多的特点,对兰炭气的利用,建议采用全低变制氢工艺,先脱油脱毒再变换。用两个实例说明兰炭气全低变制氢的工业应用,结果表明,兰炭气全低变制氢工艺是可行的。采用该工艺技术,可实现对兰炭气的综合利用。     

碳纳米管传感器的研究进展

综述了不同功能碳纳米管传感器(微型碳纳米管气体离子传感器、无线被动碳纳米管气体传感器、碳纳米管化学和力学传感器、碳纳米管阵列生物传感器、碳纳米管温度和风速传感器、碳纳米管神经毒气传感器)的制备、结构特点、性能和发展方向.     

External Stimuli Responsive Liquid‐Infused Surfaces Switching between Slippery and Nonslippery States: Fabrications and Applications

Surfaces with controllable liquid wettability and related functions have gained increasing attention from interfacial scientists due to the high demand of fundamental research and practical applications. Inspired by pitch plant's excellent liquid repellency, external stimuli responsive lubricant‐infused surfaces switching between slippery state and nonslippery state under external stimuli (E‐LIS) have been developed by introducing external stimuli responsive materials as substrates, lubricants, or repellent liquids. This progress report is focused on recent development of E‐LIS. First, design strategy and fabrication of E‐LIS upon external stimuli exposure, including stress, electrical field, magnetic field, and temperature, is summarized. Then, emerging interfacial applications of E‐LIS, such as microreactors, pipetting devices, fog collection devices, and so on, are highlighted. In addition, remaining challenges and future prospects are provided.     

Biomacromolecule‐Functionalized AIEgens for Advanced Biomedical Studies

The advances in bioinformatics and biomedicine have promoted the development of biomedical imaging and theranostic systems to respectively extend the endogenous biomarker imaging with high contrast and enhance the therapeutic effect with high efficiency. The emergence of biomacromolecule‐functionalized aggregation‐induced emitters (AIEgens), utilizing AIEgens, and biomacromolecules (nucleic acids, peptides, glycans, and lipids), displays specific targeting ability to cancer cell, improved biocompatibility, reduced toxicity, enhanced therapeutic effect, and so forth. This review summarizes the rational design of biomacromolecule‐functionalized AIEgens and their biomedical applications in recent ten years, including high‐resolution optical imaging of cell, tissue, and small animal model with low background; the biomarker detection for early diagnosis and prognosis; the delivery and monitoring of prodrugs; image‐guide photodynamic therapy and its combination with chemotherapy. Through illustrating their functional mechanisms and application, it is hoped that this review would open up a completely new train of research thought for attracted researchers in various fields.     

当前继电保护检验工作存在问题的分析

文章根据河北南网的运行实践,分析当前继电保护检验工作中存在的主要问题及产生原因。文章提出了解决这些问题的思路。