Sustainable disassembly line balancing model based on triple bottom line

End of life (EOL) phase of a product is receiving more attention due to increase in environmental concerns, and many studies have been conducted for value creation in EOL, focusing on concepts as remanufacturing, reuse and recycling in sustainable production manner. This study especially focuses on one of global problem, e-waste. To minimise the amount of wastes and maximise recovered materials from EOL, disassembly is one of the most important concept, associated with reuse, and balancing disassembly line in an optimal way is essential for organisations. In disassembly line balancing (DLB), not only precedence of tasks, but also risk criteria related to environment and human safety should be considered for sustainability. The aim of this study is to propose a model based on triple bottom line (TBL) dimensions, i.e. human safety, environmental safety and business criteria. To achieve sustainability in DLB, and for risk assessment in sustainable DLB, it had been decided to use a multi-criteria method, i.e. TODIM, acronym in Portuguese of ‘Tomada de Decisão Iterativa Multicritério’. The proposed model included 22 disassembly criteria categorised under TBL dimensions, which are derived from the literature. Implementation of the study was conducted for computer disassembly processes, and as a result of the study approximately 12% an improvement in cycle time was succeeded. In the long run, the integration of sustainability in disassembly operations may contribute to the competitive advantage of the company in terms of differentiation and corporate image by achieving business, environment and human targets simultaneously.     

Masking the Peroxidase-Like Activity of the Molybdenum Disulfide Nanozyme Enables Label-Free Lipase Detection

Two-dimensional MoS₂ nanoparticles (2D-nps) exhibit artificial enzyme properties that can be regulated at bio-nanointerfaces. We discovered that protein lipase is able to tune the peroxidase-like activity of MoS₂ 2D-nps, offering low-nanomolar, label-free detection and identification in samples with unknown identity. The inhibition of the peroxidase-like activity of the MoS₂ 2D-nps was demonstrated to be concentration dependent, and as low as 5 nm lipase was detected with this approach. The results were compared with those obtained with several other proteins that did not display any significant interference with the nanozyme behavior of the MoS₂ 2D-nps. This unique response of lipase was characterized and exploited for the successful identification of lipase in six unknown samples by using qualitative visual inspection and a quantitative statistical analysis method. The developed methodology in this approach is noteworthy for many aspects; MoS₂ 2D-nps are neither labeled with a signaling moiety nor modified with any ligands for signal readout. Only the intrinsic nanozyme activity of the MoS₂ 2D-nps is exploited for this detection approach. No analytical equipment is necessary for the visual detection of lipase. The synthesis of the water-soluble MoS₂ 2D-nps is low costing and can be performed in bulk scale. Exploring the properties of 2D-nps and their interactions with biological materials reveals highly interesting yet instrumental features that offer the development of novel bioanalytical approaches.     

The hydro-abrasive erosion wear behavior of duplex-treated surfaces of AISI H13 tool steel

The influence of duplex surface treatments consisting of a DC-pulsed plasma nitriding process and subsequent coatings of CrN and TiAlN deposited by physical vapor deposition(PVD)on AISI H13 tool steel was studied in this article.The treated samples were characterized using metallographic techniques,SEM,EDS,and microhardness methods.Hydro-abrasive erosion wear tests were performed in a specifically designed wear tester in which the samples were rotated in a wear tank containing a mixture of distilled water and ceramic abrasive chips with a fixed rotational speed.The wear rates caused by the abrasive particle impacts were assessed based on accumulated weight loss measurements.The worn surfaces were also characterized using optical microscopy,SEM,and EDS.Microhardness measurements indicated a significant increase in the surface hardness of the duplex-treated samples.The surfaces of the samples with the TiAlN coating were approximately 15 times harder than that of the untreated samples and 3 times that of the plasma nitrided samples.Hydro-abrasive erosion wear results showed that the duplex surface treatments,especially the CrN coating,displayed the highest erosion wear resistance.     

The Random <Emphasis Type="Italic">J</Emphasis>-Model with Biquadratic Interaction

The spin-1 model is studied on the Bethe lattice by including the bilinear J and biquadratic K exchange interactions into the Hamiltonian. The effects of J is randomized by using a bimodal random distribution with an adjustable parameter α which allows to study the cases of ±J-model and bond-dilution. The thermal variations of the order-parameters are studied to obtain the possible phase diagrams of the model. It is found that second-order phase transitions lines separate the ordered-phases, ferromagnetic, or antiferromagnetic, from the disordered one, i.e., the paramagnetic phase. The staggered quadrupolar phase lines are also found and only seen for higher negative K values for coordination number q=4 and 6, only. The reentrant behavior is also found for some of the phase transitions lines.     

Switchable Fluorescence of Doxorubicin for Label-Free Imaging of Bioorthogonal Drug Release

Monitoring the release and activation of prodrug formulations provides essential information about the outcome of a therapy. While the prodrug delivery can be confirmed by using different imaging techniques, confirming the release of active payload by using imaging is a challenge. Here, we have discovered that the switchable fluorescence of doxorubicin can validate drug release upon its uncaging reaction with a highly specific chemical partner. We have observed that the conjugation of doxorubicin with a trans-cyclooctene (TCO) diminishes its fluorescence at 595 nm. This quenched fluorescence of the doxorubicin prodrug is recovered upon its bond-cleaving reaction with tetrazine. Clinically assessed iron oxide nanoparticles were used to formulate a doxorubicin nanodrug. The release of doxorubicin from the nanodrug was studied under various experimental conditions. A fivefold increase in doxorubicin fluorescence is observed after complete release. The studies were carried out in vitro in MDA-MB-231 breast cancer cells. An increase in Dox signal was observed upon tetrazine administration. This switchable fluorescence mechanism of Dox could be employed for fundamental studies, that is, the reactivity of various tetrazine and TCO linker types under different experimental conditions. In addition, the system could be instrumental for translational research where the release and activation of doxorubicin prodrug payloads can be monitored by using optical imaging systems.     

Object manipulation with a variable-stiffness robotic mechanism using deep neural networks for visual semantics and load estimation

Neural Computing and Applications - In recent years, the computer vision applications in the robotics have been improved to approach human-like visual perception and scene/context understanding....     

Evaluation of form error at semi-spherical tools by use of image processing

In this study, a method is proposed for dimensional measurements of semi-spherical parts for the standard tool electrodes used in Electrical Discharge Machining (EDM). The tool electrode to be measured is magnified by a profile projector. Pictures of some equatorial plane projections of the electrodes are captured by a digital camera before and after machining. The pictures were calibrated with the geometric camera calibration. Then, the profiles are extracted from their background using the adaptive threshold, which is an image processing method. 2D coordinates are first obtained and then converted to 3D coordinates. Using the obtained data, sphericity and radius are calculated by means of the minimum zone method. It is seen that the proposed method can be used for determining the EDM tool electrodes’ form error.