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Chemical Property and Antibacterial Activity of Metronidazole-decorated Ti through Adhesive Dopamine
In order to present a novel metronidazole-decorated Ti implanted with antibacterial activity through adhesive dopamine, and prepare metronidazole-decorated Ti, Ti substrates were pre-modified with dopamine(DA) coating, and metronidazole was subsequently immobilized onto the surface of DA-modified Ti substrates. The prepared MET-decorated Ti interfaces were prepared for surface characterization tests:contacting angle measurements, scanning electron microscope, ATR-FTIR spectroscopy and in vitro anti-biofilm formation assay. Statistical tests were performed using by SPSS16.0. Contacting angle measurement, scanning electron microscopy, and ATR-FTIR spectroscopy confirmed the successful presence of MET grafted on the Ti surface. In addition, the MET-decorated Ti induced good in vitro antibacterial activity toward Escherichia coli and Streptococcus mutans,Gram-negative and Gram-positive bacteria, respectively. The modified Ti substrate with enhanced antibacterial activity holds a great potential as implanting material for applications in dental and bone graft substitutes. 相似文献
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中部等截面梭形柱的试验研究及有限元分析 总被引:1,自引:1,他引:0
对西安咸阳国际机场二期扩建工程T3A航站主楼3根梭形柱进行1∶2缩尺破坏性稳定试验研究,分析轴压梭形钢管柱在一端固接、一端铰接约束下的稳定极限承载力,并探讨其破坏特性和机理。试验结果表明,其极限承载力达到设计荷载的2倍以上,满足设计要求。同时,采用有限元方法对试验进行模拟,并与试验得到的稳定极限承载力、破坏形状、荷载-位移曲线等进行对比,二者吻合较好。此外,基于有限元分析可知:试件长度比α增大,极限承载力提高;试件楔率γ增大,极限承载力降低;同时给出楔率γ与极限承载力Pu的拟合公式。 相似文献
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