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1.
Improved load following capability is one of the main technical performances of advanced PWR (APWR). Controlling the nuclear reactor core during load following operation encounters some difficulties. These difficulties mainly arise from nuclear reactor core limitations in local power peaking, while the core is subject to large and sharp variation of local power density during transients. Axial offset (AO) is the parameter usually used to represent of core power peaking, in form of a practical parameter. This paper, proposes a new intelligent approach to AO control of PWR nuclear reactors core during load following operation. This method uses a neural network model of the core to predict the dynamic behavior of the core and a fuzzy critic based on the operator knowledge and experience for the purpose of decision-making during load following operations. Simulation results show that this method can use optimum control rod groups maneuver with variable overlapping and may improve the reactor load following capability.  相似文献   
2.
Although the response of the right ventricle (RV) to the increased afterload is an important determinant of the patient outcome, very little is known about the underlying mechanisms. Mast cells have been implicated in the pathogenesis of left ventricular maladaptive remodeling and failure. However, the role of mast cells in RV remodeling remains unexplored. We subjected mast cell-deficient WBB6F1-KitW/W-v (KitW/KitW-v) mice and their mast cell-sufficient littermate controls (MC+/+) to pulmonary artery banding (PAB). PAB led to RV dilatation, extensive myocardial fibrosis, and RV dysfunction in MC+/+ mice. In PAB KitW/KitW-v mice, RV remodeling was characterized by minimal RV chamber dilatation and preserved RV function. We further administered to C57Bl/6J mice either placebo or cromolyn treatment starting from day 1 or 7 days after PAB surgery to test whether mast cells stabilizing drugs can prevent or reverse maladaptive RV remodeling. Both preventive and therapeutic cromolyn applications significantly attenuated RV dilatation and improved RV function. Our study establishes a previously undescribed role of mast cells in pressure overload-induced adverse RV remodeling. Mast cells may thus represent an interesting target for the development of a new therapeutic approach directed specifically at the heart.  相似文献   
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Metallurgical and Materials Transactions B - This study investigates the effect of sintering temperature on the compression strength of nickel foams in an inert atmosphere. The nickel foams were...  相似文献   
4.
The paper presents further experiments with an extended version of a comprehensive model for assessment of energy technologies and research and development (R&D) planning to evaluate the impact of innovation programs on development of Iranian electricity-supply system. This analytical instrument is a model of energy R&D resource allocation with an explicit perspective of developing countries which has been linked to a bottom-up energy-systems model. Three emerging electricity generation technologies of solar PV, wind turbine and gas fuel cell are considered in the model and the impact of innovation programs on cost-reducing innovation for them is examined. The main results provided by the modeling approach include optimal allocation of R&D resources, induced capacity expansion policies to guarantee the effectiveness of R&D activities, competitive cost of emerging technologies, impact of innovation programs on optimal structure of electricity-supply system and benefits of innovation programs in the long-run.  相似文献   
5.
OBJECTIVE: To compare the effects of aerosolization of prostacyclin and its stable analog iloprost with those of nasal oxygen, inhaled nitric oxide, and intravenous prostacyclin on hemodynamics and gas exchange in patients with severe pulmonary hypertension. DESIGN: Open uncontrolled trial. SETTING: Justus-Liebig-University, Giessen Germany. PATIENTS: 4 patients with primary pulmonary hypertension and 2 patients with severe pulmonary hypertension associated with calcinosis, the Raynaud phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia (the CREST syndrome). All were classified as New York Heart Association class III or class IV. INTERVENTION: Short-term applications of O2, inhaled nitric oxide, intravenous prostacyclin, aerosolized prostacyclin, and aerosolized iloprost during repeated catheter investigation of the right side of the heart within a 1-month period. One patient had long-term therapy with inhaled iloprost. RESULTS: Aerosolized prostacyclin decreased pulmonary artery pressure in 6 patients from (mean +/- SE) 62.3 +/- 4.1 mm Hg to 50.8 +/- 5.5 mm Hg and reduced pulmonary vascular resistance from 1721 +/- 253 dyne/s cm-5 to 1019 +/- 203 dyne/s cm-5, and it increased cardiac output from 2.75 +/- 0.21 L/min to 4.11 +/- 0.54 L/min, mixed venous oxygen saturation from 51.1% +/- 3/4% to 66.3% +/- 4.1% and arterial oxygen saturation from 90.6% +/- 2.7% to 93.8% +/- 23% (P<0.05 for all changes). Mean systemic arterial pressure was only slightly affected. The responses lasted for 10 to 30 minutes after inhalation was terminated. Aerosolized iloprost had an identical efficacy profile but was associated with a longer duration of the pulmonary vasodilatory effect (60 min to 120 min). In comparison, intravenous prostacyclin reduced pulmonary vascular resistance with corresponding efficacy but produced a more pronounced decline in systemic artery pressure and no clinically significant decrease in pulmonary artery pressure. Nitric oxide and O2 were less potent pulmonary vasodilators in these patients. In one patient, 1 year of therapy with aerosolized iloprost (100 microgram/d in six aerosol doses) resulted in sustained efficacy of the inhaled vasodilator regimen and clinical improvement. CONCLUSION: Aerosolization of prostacyclin or its stable analog iloprost causes selective pulmonary vasodilatation, increases cardiac output, and improves venous and arterial oxygenation in patients with severe pulmonary hypertension. Thus, it may offer a new strategy for treatment of this disease.  相似文献   
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The aim of this study was to investigate the effect of nano-silver treatment on some physical and mechanical properties of compressed low density wood species. Wood specimens were prepared from spruce (Picea abies), impregnated with water or nano-silver solution by empty cell process and compressed through radial direction in a hot press. The results showed that by nano-silver treatment, the spring back, bending strength (modulus of rupture) and impact load resistance were improved significantly. The best results for spring-back (0.04%) were seen in the nano-silver impregnated specimens that were compressed at 150°C for 4 hours. The modulus of rupture (MOR), modulus of elasticity (MOE) and impact load resistance in nano-silver impregnated densified specimens were gained for 53%, 41.2% and 175.7%, respectively (in comparison with controls). The maximum amounts of impact load resistance belonged to the nano-silver impregnated specimens which were compressed at press conditions of 150°C for 4 hours, showing the high ability of these specimens against high impact loads such as earthquake loads. An upcoming research (consisting of durability tests) will be done for evaluating the suitability of nano-silver impregnated densified spruce wood for exterior uses.  相似文献   
9.
In this paper, we propose a robust blind watermarking algorithm based on quantization of distance among wavelet coefficients for copyright protection. We divide wavelet coefficients into some blocks and obtain the first, second, and third maximum coefficients in each block. Then, we quantize the first and second maximum coefficients according to binary watermark bits. Using the block-based watermarking, we can extract the watermark without using the original image or watermark. The algorithm as a watermarking system has appropriate performance due to imperceptibility. In addition, experimental results also show that the proposed method is quite robust under either non-geometry or geometry attacks.  相似文献   
10.
The purpose of this study was to systematically synthesize and characterize the high surface area 10 wt% nanocomposites of α‐Fe2O3 (hematite)/silica using a simple and economically effective homogenous precipitation (HP) route via Response Surface Method combined with Central Composite Design (CCD). Accordingly, the RSM‐CCD approach including 20 experiments was designed to investigate the effects of three factors including concentration of iron chloride solution, pH and calcinations temperature on the final surface area of α‐Fe2O3/silica nanocomposites. The optimum surface area was 373 m2/g at the condition including iron chloride concentration of 0.018 mol/L, pH=8.95, and calcination temperature of 573°C.  相似文献   
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