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排序方式: 共有309条查询结果,搜索用时 15 毫秒
1.
DA Bloch 《Canadian Metallurgical Quarterly》1997,53(1):73-85
Methods are proposed for comparing two diagnostic tests for the same data where a threshold for positive for each test is specified. One method contrasts the diagnostic tests' estimated risks. A second method compares the two tests' kappa coefficients. When thresholds for positive test results are specified a priori, maximum likelihood estimators and their asymptotic variances are derived and test statistics are presented for both case-control and naturalistic methods of sampling. The bootstrap is proposed as a method to assess differences in risk estimators when thresholds for positive test results are chosen by scanning the data. Examples are given to illustrate the methods. 相似文献
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DJ Schurman A Matityahu SB Goodman W Maloney S Woolson H Shi DA Bloch 《Canadian Metallurgical Quarterly》1998,(353):175-184
Postoperative knee flexion in patients undergoing Insall-Burstein-II total knee arthroplasty at 2 years was evaluated regarding two basic questions: what groups of patients gain or lose the most flexion and what groups of patients have the best or worst postoperative flexion. Thirteen preoperative variables (maximum flexion, flexion arc, tibiofemoral angle, quadriceps strength, extensor lag, Knee Society score, Knee Society patient assessment, gender, age, height, weight, diagnosis, and surgeon) and four postoperative variable (leg length change, tibiofemoral angle, distance from patella to the joint line, and the tibial prosthesis anteroposterior translation on a lateral radiograph) were used in an attempt to explain postoperative flexion. The analysis was performed on 164 consecutive Insall-Burstein-II total knees in which the data were gathered prospectively on a time oriented medical record database. A regression tree analysis was used to identify several groups of patients, characterized by preoperative factor values, who had markedly above average performance on postoperative flexion. The preoperative factors identified include preoperative flexion, flexion arc, tibiofemoral angle, extensor lag, diagnosis, and age. The only postoperative variable of significance was tibiofemoral angle. Among the potential determinants of postoperative flexion that failed to appear predictive were the Knee Society scores and surgeon. Preoperative flexion is known to be a critical determinant of postoperative flexion in total knee replacement. However, in the current study, preoperative flexion accounted for only half of the difference between the best (122 degrees) and the worst (88 degrees) group, as determined with regression tree analysis. 相似文献
4.
The focus of this article is to develop mathematical morphology on hypergraphs. To this aim, we define lattice structures on hypergraphs on which we build mathematical morphology operators. We show some relations between these operators and the hypergraph structure, considering in particular transversals and duality notions. Then, as another contribution, we show how mathematical morphology can be used for classification or matching problems on data represented by hypergraphs: thanks to dilation operators, we define a similarity measure between hypergraphs, and we show that it is a kernel. A distance is finally introduced using this similarity notion. 相似文献
5.
In this paper we use an approach based on sliding mode control to design a feedback which stabilizes the origin for the so-called nonholonomic integrator or Heisenberg system, a particular case of a canonical class of nonlinear driftless control systems of the form which fail Brockett's necessary condition for the existence of a smooth stabilizing feedback. 相似文献
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Daniel Alexander Bizjak Lucas John Lynn Matits Alisa Uhl Sebastian Victor Waldemar Schulz Jana Schellenberg Johannes Peifer Wilhelm Bloch Manfred Weiß Beate Grüner Hendrik Bracht Jürgen Michael Steinacker Marijke Grau 《International journal of molecular sciences》2022,23(23)
Hematological and hemorheological parameters are known to be altered in COVID-19; however, the value of combined monitoring in order to deduce disease severity is only scarcely examined. A total of 44 acute SARS-CoV-2-infected patients (aCOV) and 44 age-matched healthy controls (Con) were included. Blood of aCOV was sampled at admission (T0), and at day 2 (T2), day 5 (T5), day 10 (T10), and day 30 (T30) while blood of Con was only sampled once. Inter- and intra-group differences were calculated for hematological and hemorheological parameters. Except for mean cellular volume and mean cellular hemoglobin, all blood cell parameters were significantly different between aCOV and Con. During the acute disease state (T0–T5), hematological and hemorheological parameters were highly altered in aCOV; in particular, anemic conditions and increased immune cell response/inflammation, oxidative/nitrosative stress, decreased deformability, as well as increased aggregation, were observed. During treatment and convalescence until T30, almost all abnormal values of aCOV improved towards Con values. During the acute state of the COVID-19 disease, the hematological, as well as the hemorheological system, show fast and potentially pathological changes that might contribute to the progression of the disease, but changes appear to be largely reversible after four weeks. Measuring RBC deformability and aggregation, as well as oxidative stress induction, may be helpful in monitoring critically ill COVID-19 patients. 相似文献
7.
用于汽车的人机界面(HMI)正在以不同的外形尺寸出现,这些新形式以前所未见.它们正在被用于最新款汽车之中,使得用户能够安全地操作复杂的最新型信息娱乐系统.许多OEM厂商正在改造HMI解决方案,以之更适合消费者需求,同时提供更安全的驾驶体验. 相似文献
8.
Yüksel Korkmaz Behrus Puladi Kerstin Galler Peer W. Kmmerer Agnes Schrder Lina Glz Tim Sparwasser Wilhelm Bloch Andreas Friebe James Deschner 《International journal of molecular sciences》2021,22(2)
Nitric oxide (NO) binds to soluble guanylyl cyclase (sGC), activates it in a reduced oxidized heme iron state, and generates cyclic Guanosine Monophosphate (cGMP), which results in vasodilatation and inhibition of osteoclast activity. In inflammation, sGC is oxidized and becomes insensitive to NO. NO- and heme-independent activation of sGC requires protein expression of the α1- and β1-subunits. Inflammation of the periodontium induces the resorption of cementum by cementoclasts and the resorption of the alveolar bone by osteoclasts, which can lead to tooth loss. As the presence of sGC in cementoclasts is unknown, we investigated the α1- and β1-subunits of sGC in cementoclasts of healthy and inflamed human periodontium using double immunostaining for CD68 and cathepsin K and compared the findings with those of osteoclasts from the same sections. In comparison to cementoclasts in the healthy periodontium, cementoclasts under inflammatory conditions showed a decreased staining intensity for both α1- and β1-subunits of sGC, indicating reduced protein expression of these subunits. Therefore, pharmacological activation of sGC in inflamed periodontal tissues in an NO- and heme-independent manner could be considered as a new treatment strategy to inhibit cementum resorption. 相似文献
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10.
Isaie Bloch 《Architectural Design》2016,86(6):20-25
Because of their textural and sensory qualities – even or uneven, smooth or rough, cold or warm, reflective or matt – particular materials tend to evoke particular moods. But this does not mean that their nature and structure cannot be played with in order to create surprising atmospheres. London-based design practice Eragatory's ‘Intimacy’ series of interiors does just that, producing visual anomalies that distort the viewer's material understanding of space. Isaie Bloch , the firm's founder, describes how. 相似文献