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本文在脉冲延迟发生的基础上提供了一种用调相方法实现抖动调制的方案。该采用数字电路,与传统的调频方法比较具有易实现,精度高等优点,并为进一步开发出抖动测试集资打下了基础。 相似文献
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Ji Hye Kim Sei Mee Yoon Sun U. Song Sang Gyu Park Won-Serk Kim In Guk Park Jinu Lee Jong-Hyuk Sung 《International journal of molecular sciences》2016,17(9)
Hypoxia has diverse stimulatory effects on human adipose-derived stem cells (ASCs). In the present study, we investigated whether hypoxic culture conditions (2% O2) suppress spontaneous mineralization and osteogenic differentiation of ASCs. We also investigated signaling pathways and molecular mechanisms involved in this process. We found that hypoxia suppressed spontaneous mineralization and osteogenic differentiation of ASCs, and up-regulated mRNA and protein expression of Insulin-like growth factor binding proteins (IGFBPs) in ASCs. Although treatment with recombinant IGFBPs did not affect osteogenic differentiation of ASCs, siRNA-mediated inhibition of IGFBP3 attenuated hypoxia-suppressed osteogenic differentiation of ASCs. In contrast, overexpression of IGFBP3 via lentiviral vectors inhibited ASC osteogenic differentiation. These results indicate that hypoxia suppresses spontaneous mineralization and osteogenic differentiation of ASCs via intracellular IGFBP3 up-regulation. We determined that reactive oxygen species (ROS) generation followed by activation of the MAPK and PI3K/Akt pathways play pivotal roles in IGFBP3 expression under hypoxia. For example, ROS scavengers and inhibitors for MAPK and PI3K/Akt pathways attenuated the hypoxia-induced IGFBP3 expression. Inhibition of Elk1 and NF-κB through siRNA transfection also led to down-regulation of IGFBP3 mRNA expression. We next addressed the proliferative potential of ASCs with overexpressed IGFBP3, but IGFBP3 overexpression reduced the proliferation of ASCs. In addition, hypoxia reduced the osteogenic differentiation of bone marrow-derived clonal mesenchymal stem cells. Collectively, our results indicate that hypoxia suppresses the osteogenic differentiation of mesenchymal stem cells via IGFBP3 up-regulation. 相似文献
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IP多媒体子系统自从3GPP UMTS Release5后已经被加入到通用移动通信系统(UMTS)的核心网络中.现在,UMTS网络主要包含以下3个域:电路交换(CS)、分组交换(PS)和IP多媒体子系统(IMS).IMS需要同原有相对陈旧的网络电路交换(CS)网络及公用电话交换网(PSTN).本文主要针对IMS同PSTN/CS网络的互通进行了概述. 相似文献
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Jinu Park Sang-Bum Kim Jae-Mok Ha Myung-Soo Kim Hong-Soo Park Hyun-Sik Hahm 《Korean Journal of Chemical Engineering》2001,18(4):468-474
The crystallization of the [Ga]-MFI was investigated as a function of synthesis time under atmospheric pressure. The molar
composition of the reactants was 100SiO2-Ga2O3-llNa2O-llTPABr-3500H2O. The crystallinity of the [Ga]-MFT was examined by using several analytical instruments, such as XRD, XPS, XRF, FT-IR, solid-statemas-NMR, DTG/DTA, and SEM. The [Ga]-MFI was successfully synthesized under atmospheric pressure at 97 ‡C in 72 h. It was found that
the nucleation of the [Ga]-MFI took a quite long time, but the crystallization took place very fast. It is supposed that nucleation
is the rate-controlling step in the [Ga]-MFI synthesis under atmospheric pressure. Consequently, if the induction period of
the nucleation can be shortened, it would be possible to synthesize the [Ga]-MFI commercially under atmospheric pressure. 相似文献
5.
Jinu Park Sang-Bum Kim Jae-Mok Ha Hong-Soo Park Hyun-Sik Hahm 《Catalysis Letters》2001,75(1-2):125-130
The crystallization of [Ga]-MFI was investigated as a function of synthesis time under atmospheric pressure. The molar composition of the reactants was 100SiO2–Ga2O3–11Na2O–11TPABr–3500H2O. The crystallinity of [Ga]-MFI was examined using several analytical instruments, such as XRD, XPS, XRF, FT-IR, solid state MAS-NMR, and DTG/DTA. [Ga]-MFI was successfully synthesized under atmospheric pressure at 97°C in 72 h. It was found that the nucleation of [Ga]-MFI took quite a long time, but the crystallization took place very fast. It is supposed that the nucleation is the rate-controlling step in [Ga]-MFI synthesis under atmospheric pressure. Consequently, if the induction period of the nucleation can be shortened, it would be possible to synthesize [Ga]-MFI commercially under atmospheric pressure. 相似文献
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Handgrip strength is an easy measure of skeletal muscle function as well as a powerful predictor of disability, morbidity, and mortality. In order to measure grip strength, a novel fiber-optic approach is proposed and demonstrated. The strain-dependent wavelength response of fiber Bragg gratings has been utilized to obtain the strength of individual fingers. Finite-element analysis is carried out to optimize the pressure transmission from the finger to the fiber Bragg grating. The effect of stiffness of the pressurizing media, its thickness, and the effect of contact fraction are evaluated. It is found that significant enhancement in the pressure sensitivity and wavelength-tuning range is achievable by optimizing these parameters. Also the stress-induced birefringence could be reduced to an insignificant near-zero value. The device is calibrated in terms of load to convert the wavelength shift to the strength of the grip. The time-dependent wavelength fluctuation is also studied and presented. 相似文献
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文章在SanghyunAhn提出的环型备份VP(R-BVP)机制的基础上,通过在e-cycle搜索算法中增加判定条件,对于每条链路,只维护所有必要的环,仿真结果表明所需要的环和VPI数目得到了很大程度的减少。 相似文献
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A comparative study of ethylene vinyl acetate nanocomposites based on expanded graphite, multiwalled carbon nanotubes, and carbon nanofibers has been carried out to investigate the effect of different carbon nanofillers on the electrical properties of the corresponding composites. The composites were prepared by ultrasonic dispersion of fillers in ethylene vinyl acetate solution, followed by casting and compression molding. The dependence of AC conductivity and dielectric constant on the frequency and filler concentration was investigated. Carbon nanofibers provided maximum conductivity as well as lowest percolation threshold (8.2 vol%) compared to expanded graphite and multiwalled carbon nanotubes filled composites. The improvement in both electrical conductivity and dielectric constant was attributed to the high filler aspect ratio and the formation of conducting networks. The relationship of dielectric constant with filler volume fraction for all the composite systems is estimated using a power law. The pressure sensing capability of the composites at respective percolation thresholds was also compared. POLYM. COMPOS., 2010. © 2009 Society of Plastics Engineers 相似文献