Assumptions and Consequences of Treating Providers in Therapy Studies as Fixed Versus Random Effects: Reply to Crits-Christoph, Tu, and Gallop (2003) and Serlin, Wampold, and Levin (2003).

In their comments on the authors' article (see record 2003-10163-009), R. C. Serlin, B. E. Wampold, and J. R. Levin (see record 2003-10163-011) and P. Crits-Christoph, X. Tu, and R. Gallop (see record 2003-10163-010) took issue with the authors' suggestion to evaluate therapy studies with nested providers with a fixed model approach. In this rejoinder, the authors' comment on Serlin et al's critique by showing that their arguments do not apply, are based on misconceptions about the purpose and nature of statistical inference, or are based on flawed reasoning. The authors also comment on Crits-Christoph et al's critique by showing that the proposed approach is very similar to, but less inclusive than, their own suggestion. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Investigation of long term drift of an intraocular pressure sensor

Microsystem Technologies - “Zero drift” behavior of an optical intraocular pressure sensor is studied using an analytical model based on the deflection of a circular membrane. Results...     

Twin-image suppression in digital in-line holography based on wave-front filtering

Pattern Analysis and Applications - Digital holography is an imaging process able to recreate three-dimensional representations of objects from recording pattern interference among distinct waves....     

On the composition of ISO 25964 hierarchical relations (BTG,BTP, BTI)

Knowledge organization systems (KOS) can use different types of hierarchical relations: broader generic (BTG), broader partitive (BTP), and broader instantial (BTI). The latest ISO standard on thesauri (ISO 25964) has formalized these relations in a corresponding OWL ontology (De Smedt et al., ISO 25964 part 1: thesauri for information retrieval: RDF/OWL vocabulary, extension of SKOS and SKOS-XL. http://purl.org/iso25964/skos-thes, 2013) and expressed them as properties: broaderGeneric, broaderPartitive, and broaderInstantial, respectively. These relations are used in actual thesaurus data. The compositionality of these types of hierarchical relations has not been investigated systematically yet. They all contribute to the general broader (BT) thesaurus relation and its transitive generalization broader transitive defined in the SKOS model for representing KOS. But specialized relationship types cannot be arbitrarily combined to produce new statements that have the same semantic precision, leading to cases where inference of broader transitive relationships may be misleading. We define Extended properties (BTGE, BTPE, BTIE) and analyze which compositions of the original “one-step” properties and the Extended properties are appropriate. This enables providing the new properties with valuable semantics usable, e.g., for fine-grained information retrieval purposes. In addition, we relax some of the constraints assigned to the ISO properties, namely the fact that hierarchical relationships apply to SKOS concepts only. This allows us to apply them to the Getty Art and Architecture Thesaurus (AAT), where they are also used for non-concepts (facets, hierarchy names, guide terms). In this paper, we present extensive examples derived from the recent publication of AAT as linked open data.     

Semi-Supervised Deep Learning for Multi-Tissue Segmentation from Multi-Contrast MRI

Journal of Signal Processing Systems - Segmentation of thigh tissues (muscle, fat, inter-muscular adipose tissue (IMAT), bone, and bone marrow) from magnetic resonance imaging (MRI) scans is useful...     

Widely Tunable Continuous-Wave Mid-Infrared Laser Source Based on Difference-Frequency Generation in AgGaS(2)

We demonstrate difference-frequency generation in the 6.8-12.5-mum range by mixing two high-power single-frequency laser diodes in a type II AgGaS(2) crystal. This compact all-solid-state scheme provides maximum output powers that exceed 1 muW and permits continuous adjustment-free scans larger than 2 cm(-1) across the entire tuning range.     

Chlorpropamide-induced hypoglycemia: successful treatment with diazoxide

A healthy adolescent boy was treated on two occasions for an overdose of chlorpropamide (Diabinese). Glucose therapy alone was not sufficient to control the hypoglycemia, but the administration of glucose plus diazoxide raised the blood sugar to supranormal levels. A bolus of intravenous glucagon briefly raised the blood sugar level to within normal limits, increased the blood ketones but also augmented insulin secretion. An overdose of sulfonylurea may cause prolonged and fatal hypoglycemia. Rational therapy, both in diabetic and normal persons, is glucose plus an "insulin antagonist." The administration of diazoxide was effective in our patient, substantially reducing the plasma insulin level; this agent may be the "insulin-antagonist" of choice for use in sulfonylurea-induced hypoglycemia.     

Remembering the Good, Forgetting the Bad: Intentional Forgetting of Emotional Material in Depression.

The authors examined intentional forgetting of negative material in depression. Participants were instructed to not think about emotional nouns that they had learned to associate with a neutral cue word. The authors provided participants with multiple occasions to suppress the unwanted words. Overall, depressed participants successfully forgot negative words. Moreover, the authors obtained a clear practice effect. However, forgetting came at a cost: Compared with the nondepressed participants and with the depressed participants who were instructed to forget positive words, depressed participants who were instructed to forget negative words showed significantly worse recall of the baseline words. These results indicate that training depressed individuals in intentional forgetting could prove to be an effective strategy to counteract automatic ruminative tendencies and mood-congruent biases. (PsycINFO Database Record (c) 2010 APA, all rights reserved)