Memes in a Digital World: Reconciling with a Conceptual Troublemaker

This paper re‐examines the concept of “meme” in the context of digital culture. Defined as cultural units that spread from person to person, memes were debated long before the digital era. Yet the Internet turned the spread of memes into a highly visible practice, and the term has become an integral part of the netizen vernacular. After evaluating the promises and pitfalls of memes for understanding digital culture, I address the problem of defining memes by charting a communication‐oriented typology of 3 memetic dimensions: content, form, and stance. To illustrate the utility of the typology, I apply it to analyze the video meme “Leave Britney Alone.” Finally, I chart possible paths for further meme‐oriented analysis of digital content.     

Evasive Targets: Deciphering Polysemy in Mediated Humor

While polysemy has been discussed in communication studies for decades, a fundamental question has evaded systematic analysis: Which textual features make mediated texts open to multiple interpretations? Focusing on humor, we addressed this question by using a somewhat unusual point of departure–a failed intercoder reliability test. We analyzed 130 humorous forwards, of which 55 elicited disagreement between coders regarding the target of mockery and 75 were uncontroversial. Our comparative analysis yielded six textual attributes that augment polysemy in mediated humor: narrative‐valence discrepancies, unstereotypical stereotyping, debatable personality traits, self‐deprecating humor, intertextuality, and centrifugal multimodality. We demonstrate the utility of the proposed typology by analyzing public controversies stirred by humorous communication, and discuss its applicability to the study of audiences and nonhumorous genres.     

Multifactor,Sequentially Releasing Scaffolds for Tissue Engineering:Fabrication Using Solvent/Nonsolvent Sintering Technology

Biodegradable constructs, providing both mechanical support to growing tissues and timed release of biological agents, are highly desired in tissue engineering. This study aimed to develop a platform technology that responds to these challenges. Accordingly, we report herein on model systems in which microspheres of poly(suberic anhydride), containing all-trans retinoic acid (atRA), and poly(d,l -lactic acid-co-glycolic acid), containing bovine serum albumin (BSA), were co-sintered at room temperature, using a solvent/nonsolvent mixture. These scaffolds release about 60% of atRA and negligible amounts of BSA within the first five days, followed by slower and steady release of BSA. They have pores of 150–500 μm and a compressive modulus of 200 kPa. Myoblasts and fibroblasts were seeded on the loaded scaffolds and both showed enhanced proliferation rates. Based on sound thermodynamic principles of polymer science, this technology demonstrates an as yet unachieved degree of versatility. It allows for the tailoring of “intelligent” scaffolds that preserve the integrity of the incorporated agents and of advanced modalities to release various drugs in a scheduled manner.     

Comparing objective and subjective learning curves: Judgments of learning exhibit increased underconfidence with practice.

When participants studied a list of paired associates for several study-test cycles, their judgments of learning (JOLs) exhibited relatively good calibration on the 1st cycle, with a slight overconfidence. However, a shift toward marked underconfidence occurred from the 2nd cycle on. This underconfidence-with-practice (UWP) effect was very robust across several experimental manipulations, such as feedback or no feedback regarding the correctness of the answer, self-paced versus fixed-rate presentation, different incentives for correct performance, magnitude and direction of associative relationships, and conditions producing different degrees of knowing. It was also observed both in item-by-item JOLs and in aggregate JOLs. The UWP effect also occurred for list learning and for the memory of action events. Several theoretical explanations for this counterintuitive effect are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

海尔兹山纪念堂

正海尔兹山纪念堂是一个独特的纪念场所。为了纪念耶路撒冷所有阵亡的士兵,设计中包含了他们名字。这是和平年代期冀希望的象征。尽管临近耶路撒冷繁华路段,纪念堂设计为一个平静的圣经式场地,整个空间孤隐而静谧。建筑主体空间通过挖掘山体而成,形成个人或集体纪念活动的私密空间。纪念堂上方的山体,以耶路撒冷石塑造出新的曲线。纪念堂形成一个波形漏斗状结构,缓缓通向天际。这种不规则的涡旋状结构为纪念堂营造出不断变化的自然光。     

A Gel‐Based Model of Selective Cell Motility: Implications for Cell Sorting,Diagnostics, and Screening

The ability to precisely control cell‐loaded material systems is essential for in vitro testing of novel therapeutics poised to advance to clinic. In this report, unique patterns of cell migration are devised into an in vitro gel‐in‐gel model for the purpose of obtaining cell response data to potentially therapeutic chemical agonists. The model consists of co‐cultures in a cell‐loaded microgel invading an acellular “sorting” gel. Material properties including biophysical and chemical compositions of the sorting gel are carefully controlled to guide a desired cell‐specific behavior, leading to massive tumor cell invasion by amoeboid migration mechanisms. Optical transparency enables straightforward and high‐throughput measurements of outgrowth response in the presence of either chemical and photoradiation therapy. Important dosing and drug sensitivity information are obtained with the gel‐in‐gel model using no more than a light microscope, without further need for arduous genomic or proteomic screening of the tissue samples.     

Characterization of pedestrian accidents and an examination of infrastructure measures to improve pedestrian safety in Israel

The high share of pedestrian fatalities in Israel provided the impetus for this study which looked for infrastructure solutions to improve pedestrian safety. First, a detailed analysis of pedestrian accidents in 2006-2007, with an emphasis on the infrastructure characteristics involved, was performed; it found that 75% of the fatalities and 95% of the injuries occurred in urban areas, the majority of cases occurring on road sections (not at junctions). About 80% of the accidents took place when a pedestrian crossed the road, the majority of them at non-crosswalk locations or at non-signalized crosswalks. International comparisons showed that the characteristics of fatal pedestrian accidents in Israel were similar to the average pedestrian accident in Europe in terms of accident location, time, and the demographic characteristics of the victims. A typology of pedestrian fatalities in Israel was built for the years 2003-2006; it demonstrated a high share of accidents at these locations: in Jewish or mixed-population towns-not at pedestrian crossings on urban street sections, and both at pedestrian crossings and not at pedestrian crossings at urban junctions; in Arab towns; and on dual-carriageway rural roads. Second, based on a literature study, a summary of about 60 pedestrian-safety-related measures was developed. Third, to diagnose the infrastructure characteristics and deficiencies associated with pedestrian accidents, detailed field studies were carried out at 95 urban locations. A major finding revealed that more than 80% of the sites with a high concentration of pedestrian-vehicle accidents in Israel were situated on arterial multi-lane streets belonging to city centers, where on a micro-level there were no indications of major deficiencies in the basic design elements of most sites. Finally, cross-checking of the safety problems identified and the infrastructure solutions available provided lists of measures recommended for application at various types of sites. It was concluded that in order to generate a significant change in the state of pedestrian injury in Israel, a move from spot treatment to a systemic treatment of the problem is required. A systemic inquiry and the transformation of the urban road network should be performed in order to diminish the areas of vehicle-pedestrian conflicts and to significantly reduce vehicle speeds in areas of pedestrian presence and activity.     

Outbreak of subclinical mastitis in a flock of dairy goats associated with atypical Staphylococcus haemolyticus

Staphylococcus haemolyticus is a pathogen frequently isolated from dairy cows and small ruminants. However, it always appears in only a few animals and not as a major pathogen. Recently, in a dairy goat herd of approximately 250 milking animals, 25.6% (46/180 goats) had milk cultures with atypical highly mucoid colonies accompanied by elevated somatic cell counts. The isolates were identified as Staph. haemolyticus. The present study describes the steps used in an attempt to identify the bacterium and to compare it with other coagulase-negative staphylococci (CNS) including Staph. haemolyticus. Species identification performed with the API STAPH-IDENT 32 kit showed >99.4% identity confirmed by 16S rDNA sequencing tests. Microscopically the atypical Staph. haemolyticus strains showed unique cuboidal tetrad clusters reminiscent of those of the genus Sarcina. The outbreak caused by an atypical CNS underlines the need for accurate biochemical and genetic methods for ultimate identification of CNS to the species level.     

Families and Networks of Internet Memes: The Relationship Between Cohesiveness,Uniqueness, and Quiddity Concreteness

This study employs a large‐scale quantitative analysis to reveal structural patterns of internet memes, focusing on 2 forces that bind them together: the quiddities of each meme family and the generic attributes of the broader memetic sphere. Using content and network analysis of 1013 meme instances (including videos, images, and text), we explore memes' prevalent quiddity types and generic features, and the ways in which they relate to each other. Our findings show that (a) higher cohesiveness of meme families is associated with a greater uniqueness of their generic attributes; and (b) the concreteness of meme quiddities is associated with cohesiveness and uniqueness. We discuss the implications of these findings to the understanding of internet memes and participatory culture.