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1.
Capacitance and dielectric loss measurements were carried out using an Al/Cu–GeO2/Al sandwich structure for 0 to 10 vol% Cu films, 120–400 nm thick, deposited at 0.4–1.5 nm/s in the frequency and temperature range 1–106 Hz and 90–573 K, respectively. The variation of capacitance and dielectric loss with frequency and temperature follows the Goswami and Goswami model. Capacitance decreases slowly with increasing thickness and also varies with the change in deposition rate of the cermet film.  相似文献   
2.
Alternative measures of pesticide use   总被引:2,自引:0,他引:2  
tRNA (m5U54)-methyltransferase (RUMT) catalyzes the S-adenosylmethionine-dependent methylation of uridine-54 in the T psi C-loop of all transfer RNAs in E. coli to form the 54-ribosylthymine residue. However, in all tRNA structures, residue 54 is completely buried and the question arises as to how RUMT gains access to the methylation site. A 17-mer RNA hairpin consisting of nucleotides 49-65 of the T psi-loop is a substrate for RUMT. Homonuclear NMR methods in conjunction with restrained molecular dynamics (MD) methods were used to determine the solution structure of the 17-mer T-arm fragment. The loop of the hairpin exhibits enhanced flexibility which renders the conventional NMR average structure less useful compared to the more commonly found situation where a molecule exists in predominantly one major conformation. However, when resorting to softer refinement methods such as MD with time-averaged restraints, the conflicting restraints in the loop can be satisfied much better. The dynamic structure of the T-arm is represented as an ensemble of 10 time-clusters. In all of these, U54 is completely exposed. The flexibility of the T psi-loop in solution in conjunction with extensive binding studies of RUMT with the T psi C-loop and tRNA suggest that the specificity of the RUMT/ tRNA recognition is associated with tRNA tertiary structure elements. For the methylation, RUMT would simply have to break the tertiary interactions between the D- and T-loops, leading to a melting of the T-arm structure and making U54 available for methylation.  相似文献   
3.
An expression is derived for the probability of error of an N th-order selection diversity system for the case where the receiver is forced to swell on one channel for several symbols before being allowed to make a decision regarding the best channel. It is found that the time-varying nature of a fading channel causes significant degradation of the probability of error when the dwell time becomes longer than about 10% of the inverse of the fading bandwidth of the channel. The onset of degradation is a function of the signal-to-noise ratio and of the order of diversity. Specific probabilities of error are calculated for differential phase-shift keyed modulation (DPSK). However, the calculations can be done for any other modulation technique  相似文献   
4.
Almond preferences were produced by giving rats a mixture of almond and sucrose (Experiments 1-4) or saccharin (Experiment 4). A subsequent extinction procedure consisted of either repeated 2-bottle almond versus water tests (Experiment 1) or repeated exposure to almond alone (Experiments 2-4). The main independent variable was whether access to food following a session was given immediately, 30 min later, or 120 min later. No effect of extinction was found in any experiment. An important finding was that varying the delay until food access had no detectable effect. It was concluded that inadvertent flavor-food associations do not maintain preference for the flavor under extinction conditions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
5.
6.
Polyvinyl alcohol (PVA) films containing 10% w/w of a model drug, sulphathiazole, were cast from aqueous solutions and subjected to heat treatment at specific temperatures for known periods of time. Heat treatment at temperatures above the Tg of the PVA films slowed down the rate of drug release from the films. Increasing the temperature of heat treatment from 120°C to 160°C further decreased the rate of drug release. On the other hand, if the heat treatment were conducted at a temperature below the Tg e.g. at 80°C, there were insignificant differences between the release profile of sulphathiazole from heat-treated films and that from untreated films. The duration of heat treatment affected the rate of drug release to a smaller extent compared to the temperature of heat treatment. These results correlated with the heat induced changes in the morphology of, and in the extent of water uptake by the PVA films.  相似文献   
7.
Motility related protein 1 (MRP1/CD9) expression in colon cancer   总被引:1,自引:0,他引:1  
STUDY OBJECTIVES: To examine the incidence and clinical significance of prolonged air leak (PAL) in patients undergoing radical upper lobectomy and to determine potential risk factors for PAL in this group of patients. DESIGN: Retrospective review of a prospective database. SETTING: Experience of one thoracic surgeon at a tertiary care cancer center. PATIENTS: One hundred consecutive patients undergoing right upper lobectomy and mediastinal lymph node dissection for non-small cell lung cancer over an 11-year period. MEASUREMENTS: PAL was defined as an air leak lasting >7 days. Preoperative, intraoperative, and postoperative clinical data were collected and analyzed to determine the factors associated with PAL. RESULTS: PAL was the most prevalent postoperative complication, comprising 25.5% of all complications seen, and lasting an average of 12.1+/-5.3 days. In 21 of the 26 patients with PAL, this complication was the only morbidity identified. There was no statistically significant difference in patient age, gender, preoperative FEV1 and diffusion of carbon monoxide, exposure to neoadjuvant chemotherapy, status of pulmonary fissures, or pathologic stage between the PAL group vs the remaining 74 patients without this complication. A significantly greater proportion of patients with PAL had FEV1/FVC ratio < or =50% (6/26 vs 5/74; p=0.02). Patients with PAL had significantly longer median length of hospital stay (11 vs 7 days; p=0.0001). Moreover, PAL was the single most common reason for an extended length of hospitalization (21/58, 36% of all causes). CONCLUSION: PAL is an alarmingly common postoperative complication and is the most frequent cause of an extended length of hospital stay in patients undergoing radical upper lobectomy. Severe obstructive pulmonary disease predisposes patients to the development of this complication.  相似文献   
8.
Parallel parsing is currently receiving attention but there is little discussion about the adaptation of sequential error handling techniques to these parallel algorithms. We describe a noncorrecting error handler implemented with a parallel LR substring parser. The parser used is a parallel version of Cormack's LR substring parser. The applicability of noncorrecting error handling for parallel parsing is discussed. The error information provided for a standard set of 118 erroneous Pascal programs is analysed. The programs are run on the sequential LR substring parser.  相似文献   
9.
In this paper, we will discuss a methodology developed and applied in the European ITERATE project with the objective of designing experiments that will provide data to seed the numerical model of operator behaviour in different surface transport modes: road vehicles, rail transport and ships. The experiments aim to investigate how new technologies support different types of operators in different contexts. A structured approach was adopted. Firstly, an initial selection of the systems to be investigated was made, describing the support they provide for operators. Hypotheses were formulated on the effects of operator parameters on the interaction with the systems. A final selection of systems for the experiments was made, focusing on systems providing support for collision avoidance and speed management. The operator parameters (culture, attitude and personality, experience, driver state (such as fatigue) and the demands of the task) were operationalised and piloted. The next step was the development of scenarios to be implemented in a driving simulator. In the last step, the final experiments were designed and detailed.  相似文献   
10.
After repetitive potential cycling employing a high positive potential limit (>700 mV wrt Hg/HgO/ KOH) three anodic and one cathodic peak can be observed using aβ-Ni(OH)2 starting material. Anodic peaks found at 425, 470 and 555 mV in 5 mol dm?3 KOH shift to less positive potentials as the alkali concentration is increased appearing at 365, 410 and 455 mV respectively in 12.5 mol dm?3 KOH. Four anodic processes involving various pairs of coexisting phases within both theβ andα-/γ-phase system can be identified as summarized below in order of increasing positive potential: Peak A $$\begin{gathered} Peak A{\text{ }}U_\alpha ^A \to {\text{ }}V_\gamma ^A \hfill \\ Peak B{\text{ }}U_\beta ^B \to {\text{ }}V_\beta ^B \hfill \\ {\text{ }}\mathop C\limits^ + {\text{ }}U_\alpha ^C \to {\text{ }}V_\gamma ^C \hfill \\ Peak E{\text{ }}V_\beta ^B \to {\text{ }}V_\gamma ^E \hfill \\ \end{gathered} $$ Observed shifts in anodic and cathodic peak potentials are consistent with the known influence of alkali and water activity on the reversible potentials for the above processes.  相似文献   
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