Uncertainties in the determination of pyrrolizidine alkaloid levels in naturally contaminated honeys and comparison of results obtained by different analytical approaches

The contamination of honey with hepatotoxic pyrrolizidine alkaloids (PAs) is a well-known hazard for food safety. While management strategies and controls of the honey industry aim to reduce the PA levels, uncertainties remain with regard to the safety of regionally produced and marketed honey. In addition, a previous study showed large differences of results obtained after various periods of storage and apparent differences between the analytical results of different laboratories. Therefore, this study aimed at examining these uncertainties by monitoring the impact of storage on the PA and PA N-oxide (PANO) content of two freshly harvested honeys and on possible demixing effects caused by pollen settling. Additionally, three analytical approaches – target analysis with matrix-matched calibration or standard addition and a sum parameter method – were applied for a comparative analysis of 20 honeys harvested in summer 2016. All samples originated from Schleswig-Holstein in Northern Germany where the PA plant Jacobaea vulgaris is currently observed on a massive scale. The results of the time series analyses showed that PANO levels markedly decreased within a few weeks and practically reached the LOD 16 weeks after harvest. Tertiary PAs, by contrast, remained stable and did not increase as a consequence of PANO decrease. The experiments on a putative demixing, which may result in a heterogeneous distribution of PAs/PANOs, revealed that there was no such effect during storage of up to 12 weeks. A comparison of the PA/PANO levels obtained by different analytical approaches showed that in some cases the sum parameter method yielded much higher levels than the target approaches, whereas in other cases, the target analysis with standard addition found higher levels than the other two methods. In summary, the results of this study highlight uncertainties regarding the validity and comparability of analytical results and consequently regarding health risk assessment.     

可记录媒体的检测策略

可记录媒体或者一次性写入媒体在过去的几年中无疑已经成为各种光盘格式中的新贵。目前CD-R已经达到了发展的颤峰,而DVD-R正在以不容置疑的迅猛发展速度成为新一代记录媒体的先锋。尽管CD-R和DVD-R之间存在着很多的不同,它们都需要完善的品质控制。     

有线和无线宽带接入产品技术

射频存储系统的目标市场有两个，一个是宽带网络，一个是无线局域网：下图介绍的是第一公里的无线宽带接入系统。图的中央有一个中枢（hub)，它的周围是一个分布网络。这是一个包括光和电的、数据和模拟结合的网络，这种系统在中国的大城市都有广泛的部署。圆圈是飞利浦开发的一些结点、中枢和分布网络，包括放大器和光电设备。     

Online Calculation and Prediction of the Strip Temperature in a Hot Strip Finishing Mill

The paper deals with a physical model for the calculation of the strip temperature in a hot rolling mill. Beside the heat transfer from the strip to the environment in the different mill sections a sub‐model for the material properties of steel including phase transitions is introduced. For the application in a process automation system an online adaptation of the model to the current state of the mill is indispensable. The adaptation is explained in detail.     

Thermische Anmerkungen zu Zeitkonstanten von Wänden

Zusammenfassung Man erh?lt kompakte Approximationen von Laplace-übergangsfunktionen, wenn die Koeffizienten des Nenners aus den Zeitkonstanten des Systems abgeleitet werden. (üblicherweise führt dies auf das Problem der Nullstellensuche einer transzendenten Funktion.) Es ist bekannt (Gough [1], Stephenson [2]), da? für die meisten W?nde drei Zeitkonstanten ausreichen, um hinreichend genaue übergansfunktionen zu erhalten. Die Taylor-Entwicklung der Kettenmatrix im Laplaceraum wird für beliebige W?nde mit eindimensionalem W?rmestrom mit der Picard'schen Methode berechnet. Für ebene Mehrschichtw?nde ist dafür eine explizite L?sung angegeben. Die ersten N Zeitkonstanten werden n?herungsweise aus der (N+1). Ordnung der Partial-Summe der Taylor-Entwicklung berechnet. Dies wird mit einer generalisierten Pade-Approximation bewerkstelligt, die eine Totzeit enth?lt und direkt auf ein Nennerpolynom führt (ohne transzendente Wurzeln). Die Wurzeln konvergieren geometrisch zu den Eigenwerten mit wachsendem N (die Eigenwerte stellen die reziproken Zeitkonstanten dar). Die Komplexit?t der gesamten Prozedur liegt kaum über derjenigen für ein System mit konzentrierten Parametern der Ordnung N+1. Es werden Beispiele angegeben, um mit den „exakten” Frequenzg?ngen zu vergleichen.     

AgNO<Subscript>3</Subscript> spray tests: advantages,weaknesses, and various applications to quantify chloride ingress into concrete. Part 1: Non-steady-state diffusion tests and exposure to natural conditions

Within the framework of the evaluation and the prediction of chloride-induced corrosion risks, simple and rapid AgNO₃ spray tests can be proposed for various issues. This paper forms the first part of a series. In this first part, the Maultzsch procedure (spraying of 0.1-N AgNO₃ solution + K₂CrO₄) as well as the procedure based on the use of a sole AgNO₃ solution have been investigated on a broad range of concretes. These procedures have also been compared to the Collepardi procedure (spraying of 0.1-N AgNO₃ + fluoresceine). The feasibility of these colorimetric techniques on saturated specimens cast in laboratory, after non-steady-state diffusion tests carried out in various conditions, is discussed. In addition, the results obtained from applying such spray tests in field conditions on cores drilled out from various RC test specimens exposed to a marine environment (tidal zone) and to a road and cold environment (freezing-thawing cycles and spraying of deicing salts) are presented. Colorimetric methods have in particular been applied here to the assessment of the average chloride penetration depth and of its evolution versus time (kinetics). Moreover, the detection threshold of these techniques has been investigated in various environments. The possible sources of discrepancy on the results have been analysed.