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PURPOSE: The aim of this prospective, controlled, follow-up study (6 months) was to examine the effects of a multidisciplinary rehabilitation programme on perceived health-related quality of life (HRQL) in patients with prolonged musculoskeletal disorders (PMSD). The programme focused on body awareness therapy and cognitive and relaxation treatment. METHOD: The rehabilitation group comprised 122 patients, and there were 114 patients in the matched control group (CG). Both groups of patients had access to primary health care. Baseline data were compared with 6-month follow-up data within and between the groups. The following measurements were employed: HRQL (Nottingham Health Profile), body awareness, postural control, pain (VAS), pain-related medicine consumption, isometric arm muscle endurance, aerobic capacity, psychosomatic symptoms, physical and psychosocial working environment and sick leave. RESULTS: Variables that improved significantly as compared with the CG were: HRQL, anxiety, pain related to movements, psychosomatic symptoms and need for pain-related medicines. CONCLUSIONS: The multidisciplinary rehabilitation programme used here improved HRQL in patients with PMSD to a greater extent than the standard treatment provided within primary heath care (p = 0.01) at least in the short term.  相似文献   
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Consensus design is a valuable protein-engineering method that is based on statistical information derived from sequence alignments of homologous proteins. Recently, consensus design was adapted to repeat proteins. We discuss the potential of this novel repeat-based approach for the design of consensus repeat proteins and repeat protein libraries and summarize recent results from such experiments.  相似文献   
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The present work investigates the electrochemical formation of self-organized high aspect ratio TiO2 and ZrO2 nanotube layers. The formation and growth of a self-organized porous layer can be achieved directly by anodization without any templates in fluoride containing electrolytes. The morphology of the porous layers is affected by the electrochemical conditions such as the electrolyte composition, the pH and the exact polarization treatment (such as the potential sweep rate from the open-circuit potential to the anodizing potential). For Ti, nanotube layers are formed with diameters varying from approx. 20 nm to 100 nm and lengths from approx. 0.25 μm to 2.5 μm depending on the electrolytes and pH. On the other hand, for Zr, tubes of 50 nm in diameter and up to approx. 17 μm in length can be grown—a key parameter in this case is the potential sweep rate. The large difference between Ti and Zr in the achievable thickness of nanotube layers indicates a difference in the growth mechanism which may be based on the different chemical dissolution rates of electrochemically formed oxides.  相似文献   
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The international planning competition (IPC) is an important driver for planning research. The general goals of the IPC include pushing the state of the art in planning technology by posing new scientific challenges, encouraging direct comparison of planning systems and techniques, developing and improving a common planning domain definition language, and designing new planning domains and problems for the research community. This paper focuses on the deterministic part of the fifth international planning competition (IPC5), presenting the language and benchmark domains that we developed for the competition, as well as a detailed experimental evaluation of the deterministic planners that entered IPC5, which helps to understand the state of the art in the field.We present an extension of pddl, called pddl3, allowing the user to express strong and soft constraints about the structure of the desired plans, as well as strong and soft problem goals. We discuss the expressive power of the new language focusing on the restricted version that was used in IPC5, for which we give some basic results about its compilability into pddl2. Moreover, we study the relative performance of the IPC5 planners in terms of solved problems, CPU time, and plan quality; we analyse their behaviour with respect to the winners of the previous competition; and we evaluate them in terms of their capability of dealing with soft goals and constraints, and of finding good quality plans in general. Overall, the results indicate significant progress in the field, but they also reveal that some important issues remain open and require further research, such as dealing with strong constraints and computing high quality plans in metric-time domains and domains involving soft goals or constraints.  相似文献   
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Recently, a number of empirical studies have compared the performance of PCA and ICA as feature extraction methods in appearance-based object recognition systems, with mixed and seemingly contradictory results. In this paper, we briefly describe the connection between the two methods and argue that whitened PCA may yield identical results to ICA in some cases. Furthermore, we describe the specific situations in which ICA might significantly improve on PCA  相似文献   
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Streaming video over a wireless network faces several challenges such as high packet error rates, bandwidth variations, and delays, which could have negative effects on the video streaming and the viewer will perceive a frozen picture for certain durations due to loss of frames. In this study, we propose a Time Interleaving Robust Streaming (TIRS) technique to significantly reduce the frozen video problem and provide a satisfactory quality for the mobile viewer. This is done by reordering the streaming video frames as groups of even and odd frames. The objective of streaming the video in this way is to avoid the losses of a sequence of neighbouring frames in case of a long sequence interruption. We evaluate our approach by using a user panel and mean opinion score (MOS) measurements; where the users observe three levels of frame losses. The results show that our technique significantly improves the smoothness of the video on the mobile device in the presence of frame losses, while the transmitted data are only increased by almost 9% (due to reduced time locality).  相似文献   
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Format dependence implies that assessment of the same subjective probability distribution produces different conclusions about over- or underconfidence depending on the assessment format. In 2 experiments, the authors demonstrate that the overconfidence bias that occurs when participants produce intervals for an uncertain quantity is almost abolished when they evaluate the probability that the same intervals include the quantity. The authors successfully apply a method for adaptive adjustment of probability intervals as a debiasing tool and discuss a tentative explanation in terms of a naive sampling model. According to this view, people report their experiences accurately, but they are naive in that they treat both sample proportion and sample dispersion as unbiased estimators, yielding small bias in probability evaluation but strong bias in interval production. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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Cognitive computational modeling is a viable methodology for further investigation of the hitherto inconclusive findings on the cognitive benefits of dynamic versus static visualization components of instructions. This is more so as contemporary cognitive architectures such as the Adaptive Control of Thought–Rational (ACT–R) 6.0 are increasingly applied to traditional cognitive psychology research problems. The application of this methodology is, however, restricted by the limited capability of existing architectures for implementing detailed atomic motor actions such as those involved in complex skill acquisition and performance. This article presents a 2-component computational modeling methodology for investigating the cognitive processes involved in the acquisition and performance of skilled motor tasks. The approach specifies a novel combination of a sequence-of-point technique with a movement control mechanism to implement variously acquired cognitive mental task representations and their intertwined role in postlearning performance as evident in the atomic control of motor actions. This paradigm is validated for 2 experiments using incrementally developed cognitive models developed in ACT–R 6.0. The model's quantitative outputs correlate significantly with equivalent empirical human data. This has implications for multimedia instructional design, especially where rapid, transferrable skill acquisition is desired on initial exposure.  相似文献   
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