Endoplasmic reticulum Ca(2+)-ATPase in microsomal vesicles isolated from bovine retinae

Active Ca2+ transport was measured in microsomal vesicles prepared from bovine retinae and was compared with that in disk membranes of the photoreceptor cells of the same retina. The 45Ca uptake was dependent on the presence of Mg(2+)-ATP and was inhibited by vanadate or when GTP substituted for ATP. The dependence of calcium uptake on the external free Ca2+ concentration gave a KM = 13 microM or a KM = 0.1 microM for disks and microsomal vesicles, respectively. A phosphorylated intermediate (E-P) of Ca(2+)-ATPase of about 100 kDa was isolated in microsomal vesicles. The E-P formation was strongly inhibited by thapsigargin and partially by 2,5-di-(-butyl)benzohydroquinone. Digestion of disks or microsomes with calpain had no effect on the phosphorylated intermediate, while digestion with trypsin produced two fragments of approximately 55 kDa and 35 kDa. These results suggest that bovine retinal microsomes contain a calcium pump belonging to the SERCA family.     

A study on the stability of superconducting YBa2Cu3O7−x phase

The thermal stability of the superconducting phase of nominal composition YBa₂Cu₃O_7–x -sintered pellets has been studied with respect to different temperatures (ranging from 300 to 950° C), time (ranging from 1 to 72 h), oxygen partial pressure (from 4 Pa to 1 atm) and carbon dioxide partial pressure (from 10^–4 Pa to 1 atm). Annealed samples were characterized by X-ray diffraction analysis, optical microscopy, and resistive measurements of the superconductive transition temperature. A stability field of the orthorhombic and tetragonal phases was obtained, showing a region of coexistance. The decomposition of the 1 2 3 phase is found to be strongly influenced by the presence of a small amount of CO₂ (1 p.p.m.) in the sintering atmosphere. A sintering process is proposed to avoid the formation of by-products.     

The effectiveness of the combined use of VIX and Support Vector Machines on the prediction of S&P 500

The aim of this research is to analyse the effectiveness of the Chicago Board Options Exchange Market Volatility Index (VIX) when used with Support Vector Machines (SVMs) in order to forecast the weekly change in the S&P 500 index. The data provided cover the period between 3 January 2000 and 30 December 2011. A trading simulation is implemented so that statistical efficiency is complemented by measures of economic performance. The inputs retained are traditional technical trading rules commonly used in the analysis of equity markets such as Relative Strength Index, Moving Average Convergence Divergence, VIX and the daily return of the S&P 500. The SVM identifies the best situations in which to buy or sell in the market. The two outputs of the SVM are the movement of the market and the degree of set membership. The obtained results show that SVM using VIX produce better results than the Buy and Hold strategy or SVM without VIX. The influence of VIX in the trading system is particularly significant when bearish periods appear. Moreover, the SVM allows the reduction in the Maximum Drawdown and the annualised standard deviation.     

Adsorption on activated carbon in countercurrent flow: An experimental study

The work describes adsorption experiments from aqueous solutions on activated carbon using a counter-current adsorber. Phenol and paranitrophenol were used for single component adsorption and molasses colour for multicomponent adsorption experiments. Isotherms were determined using simple equilibrium experiments. Three different techniques were used for determination of the kinetics. These were finite bath, infinite bath and fixed bed experiments. A mathematical model for countercurrent adsorption was tested. The model includes the effect of film diffusion and pore diffusion as well as surface diffusion, and can handle systems with a nonlinear isotherms. Kinetic data in the form of an average diffusivity in the carbon determined from the finite bath experiments and isotherm data did not predict the operation of the countercurrent column well. Data from the fixed bed experiments predicted countercurrent column operation much better. This is deemed to be due to inhomogeneities in the carbon used, resulting in a fairly quick initial uptake of the main part of the solute and a slower uptake of a minor amount.     

Hysteretic Critical State in Coplanar Josephson Junction with Monolayer Graphene Barrier

Coplanar Al/graphene/Al junctions fabricated on the same graphene sheet deposited on silicon carbide (SiC), show robust Josephson coupling at subKelvin temperature, when the separations between the electrodes is below 400 nm. Remarkably, a hysteretic Critical State sets in when ramping an orthogonal magnetic field, with a sudden collapse of the Josephson critical current I _c when turning the field on, and a revival of I _c when inverting the sweep. Similar hysteresis can be found in granular superconducting films which may undergo the Berezinskii-Kosterlitz-Thouless transition. Here, we give quantitative arguments to prove that this odd behavior of the magnetoconductance gives evidence for an incipient Berezinskii-Kosterlitz-Thouless transition with drift and pinning of fluctuating free vortices induced by the current bias.     

ISS feedback control redesign for continuous stirred tank reactors

In this paper a new nonlinear feedback control law for continuous stirred tank reactors, obtained by exact Input/Output (I/O) linearization and Sontag's input‐to‐state stability feedback control redesign methods, is studied. By the new feedback control law, a significant attenuation of the disturbance effect is guaranteed, with evident improvement with respect to control laws obtained by the exact I/O linearization method. The performed simulations validate the theoretical results. Copyright © 2010 John Wiley & Sons, Ltd.     

Modeling and gradient pattern analysis of irregular SFM structures of porous silicon

Technological applications in opto-electronic devices have increased the interest in characterizing porous silicon structure patterns. Due to its physical properties, solutions from KPZ 2D are adopted to simulate the structure of porous material interface whose spatial characteristics are equivalent to those found in porous silicon samples. The analysis of the simulated and real Scanning Force Microscopy (SFM) surfaces was done using the Gradient Pattern Analysis (GPA). We found that the KPZ 2D model presented asymmetry levels compatible with the irregular surfaces observed by means of SFM images of π-Si.     

The Liapunov's second method for continuous time difference equations

Among many other cases such as economic and lossless propagation models, continuous time difference equations are encountered as the internal dynamics in a class of non‐linear time delay systems, when controlled by a suitable state feedback which drives the output exponentially to zero. The Liapunov's second method for these infinite dimensional systems has not been extensively investigated in the literature. This paper has the aim of filling this gap. Liapunov's second method theorems for checking the stability and the asymptotic stability of this class of infinite dimensional systems are built up, in both a finite and an infinite dimensional setting. In the finite dimensional setting, the Liapunov function is defined on finite dimensional sets. The conditions for stability are given as inequalities on continuous time. No derivatives are involved, as in the dynamics of the studied systems. In the infinite dimensional setting, the continuous time difference equation is transformed into a discrete time system evolving on an infinite dimensional space, and then the classical Liapunov theorem for the system in the new form is written. In this paper the very general case is considered, that is non‐linear continuous time difference equations with multiple non commensurate delays are considered, and moreover the functions involved in the dynamics are allowed to be discontinuous, as well as the initial state. In order to study the stability of the internal dynamics in non‐linear time delay feedback systems, an exogenous disturbance is added, which goes to zero exponentially as the time goes to infinity. An example is considered, from non‐linear time delay feedback theory. While the results available in the literature are inconclusive as far as the stability of that example is concerned, such stability is proved to hold by the theorems developed in this paper, and is validated by simulation results. Copyright © 2003 John Wiley & Sons, Ltd.