Computational intelligence for microarray data and biomedical image analysis for the early diagnosis of breast cancer

The objective of this paper was to perform a comparative analysis of the computational intelligence algorithms to identify breast cancer in its early stages. Two types of data representations were considered: microarray based and medical imaging based. In contrast to previous researches, this research also considered the imbalanced nature of these data. It was observed that the SMO algorithm performed better for the majority of the test data, especially for microarray based data when accuracy was used as performance measure. Considering the imbalanced characteristic of the data, the Naive Bayes algorithm was seen to perform highly in terms of true positive rate (TPR). Regarding the influence of SMOTE, a well-known imbalanced data classification technique, it was observed that there was a notable performance improvement for J48, while the performance of SMO remained comparable for the majority of the datasets. Overall, the results indicated SMO as the most potential candidate for the microarray and image dataset considered in this research.     

An S-shaped relationship between changes in appraisals and changes in emotions.

Previous research on appraisal theories of emotion has shown that emotions and appraisals are related but has not specified the nature of the relationships. This research examined the functional forms of appraisal-emotion relationships and demonstrated that for all seven appraisals studied, appraisals relate to emotions in an S-shaped (ogival) fashion: Changes in appraisals at extreme levels are associated with only small changes in emotions, but changes at moderate levels are associated with substantial changes in emotions. With a few exceptions, ogival relationships were found for the relationships between seven appraisals (Goal Achievement Expectancy, Agency, Control, Certainty, Fairness, Pleasantness, and Motive Congruence) and numerous relevant emotions across different sample-types, cultures, and methods. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Amae in Japan and the United States: An exploration of a "culturally unique" emotion.

The experience of an emotion considered to be culturally unique (i.e., Japanese Amae) was tested in the United States, where there is no word to describe the concept. North American and Japanese participants read scenarios in which a friend made an inappropriate request (Amae), made no request, or made the request to another friend. Both American and Japanese participants felt more positive emotion and perceived the requester as feeling closer to them in the Amae condition than in the other two conditions. However, Americans felt more in control when asked for a favor than when not asked, a pattern that did not emerge among the Japanese. Cultural specificity of hypocognized emotions is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

MDSM: Microarray database schema matching using the Hungarian method

Current microarray databases use different terminologies and structures and thereby limit the sharing of data and collating of results between laboratories. Consequently, an effective integrated microarray data model is required. One important process to develop such an integrated database is schema matching. In this paper, we propose an effective schema matching approach called MDSM, to syntactically and semantically map attributes of different microarray schemas. The contribution from this work will be used later to create microarray global schemas. Since microarray data is complex, we use microarray ontology to improve the measuring accuracy of the similarity between attributes. The similarity relations can be represented as weighted bipartite graphs. We determine the best schema matching by computing the optimal matching in a bipartite graph using the Hungarian optimisation method. Experimental results show that our schema matching approach is effective and flexible to use in different kinds of database models such as; database schema, XML schema, and web site map. Finally, a case study on an existing public microarray schema is carried out using the proposed method.     

Through the looking glass darkly? When self-doubts turn into relationship insecurities.

The authors argue that individuals regulate perceptions of their relationships in a self-protective way, finding virtue in their partners only when they feel confident that their partners also see virtues in them. In 4 experiments, the authors posed an acute threat to low and high self-esteem individuals' feelings of self-worth (e.g., guilt about a transgression, fears of being inconsiderate or intellectually inept). They then collected measures of confidence in the partner's positive regard and acceptance (i.e., reflected appraisals) and perceptions of the partner. The results revealed that low self-esteem individuals reacted to self-doubt with heightened doubts about their partners' regard, which then tarnished impressions of their partners. In contrast, high self-esteem individuals reacted to self-doubts by becoming more convinced of their partners' continued acceptance, using their relationships as a resource for self-affirmation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

On our failure to disconfirm what nobody ever said.

Responds to criticisms (e.g., C. E. Izard, see record 1981-31548-001) of the present authors' (see record 1981-00499-001) article. The present authors provide additional methodological detail demonstrating that most of the methodological criticisms are mistaken or irrelevant to the hypothesis that they intended to test. (14 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Juror comprehension and public policy: Perceived problems and proposed solutions.

Laypersons, the media, and many legal scholars tend to attribute problems in the jury system to the dispositions of individual jurors and to recommend reforms in jury selection procedures and relaxation of the unanimity rule. Social scientists view problems as a consequence of the structure of the jurors' task and recommend reforms in trial procedures. After years of apathy, the legal system has proposed, and in some jurisdictions implemented, a variety of reforms, most of which are based on the social science perspective that the problem is not due to bad jurors but to unnecessary procedural obstacles to high-quality decision making. These reforms are described in the final section of the article. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Valuing a wind farm construction: A contingent valuation study in Greece

Our analysis is based on data from a double-bounded dichotomous choice contingent valuation study implemented to elicit public attitudes towards renewable energy generation and their willingness to pay for the construction of a wind farm in the area of Messanagros in the island of Rhodes, Greece. Results indicate that there are significant positive values deriving from the proposed project. Respondents report a mean willingness to pay a premium in their bi-monthly electric bills of €8.86 for the sole purpose of the construction of the wind farm. The estimated economic benefits to the local population are weighed against the investment cost in a cost–benefit analysis to inform policy making and implications for EU energy policy are provided.     

Highlights for more complete sports video summarization

Summarization is an essential requirement for achieving a more compact and interesting representation of sports video contents. We propose a framework that integrates highlights into play segments and reveal why we should still retain breaks. Experimental results show that fast detections of whistle sounds, crowd excitement, and text boxes can complement existing techniques for play-breaks and highlights localization.     

Quantitative determination of amino acid levels in neutral and glucosamine-containing carbohydrate polymers

OBJECTIVE: To determine whether local cardiac angiotensin converting enzyme (ACE) expression is upregulated during the development of hypoxia-induced right ventricular hypertrophy. METHODS: ACE activity was measured in membrane preparations from the right ventricle and left ventricle plus septum in normoxic rats and animals exposed to chronic hypoxia for 8 and 14 days. Local cardiac ACE expression was studied by immunohistochemistry using a monoclonal antibody to ACE (9B9). RESULTS: In the normal rat heart, ACE expression was confined to vascular endothelium, the valvular endocardium, and localized regions of parietal endocardium. We found that the development of pulmonary hypertension and right ventricular hypertrophy were associated with 2.6- and 3.4-fold increases in membrane-bound right ventricular ACE activity by 8 and 14 days of hypoxia, respectively. Right ventricular ACE activity was positively correlated with the degree of right ventricular hypertrophy (r = 0.83, P < 0.001). In contrast, left ventricular plus septal ACE activity was significantly reduced by approximately 40 and 60% by 8 and 14 days of hypoxia, respectively, compared to controls. In the right ventricle of chronically hypoxic rats, immunohistochemistry demonstrated increased ACE expression in areas of myocardial fibrosis. Interestingly, increased ACE expression was noted in the right ventricular epicardium in chronically hypoxic rats. In the free wall of the left ventricle there was a significant reduction in the number of myocardial capillaries which expressed ACE in chronically hypoxic rats. CONCLUSION: Chronic hypoxia has a differential effect on left and right ventricular ACE activity and that the sites of altered ACE expression are highly localized. We speculate that locally increased right ventricular ACE activity and expression may play a role in the pathogenesis of right ventricular hypertrophy secondary to hypoxic pulmonary hypertension.