Ferromagnetic nano model study for the peristaltic flow in a plumb duct with permeable walls

Microsystem Technologies - The purpose of the present enquiry is to analyse the mechanics of an incompressible fluid, with water as base fluid, through a radially symmetric plumb duct with...     

Identification of the DRB1*1313 allele in a sibling pair

Amines such as dopamine, norepinephrine and epinephrine were analysed in the brain regions of O.mossambicus exposed to quinalphos, phenthoate and their combination for 96 hr. The three types of treatments significantly (P < 0.05) altered the amines level at various intervals in the brain regions.     

Utility of stereoscopic displays for indirect-vision driving and robot teleoperation

The effectiveness of an active shutter-glasses stereoscopic display (SD) and a passive polarised SD was evaluated in a live robot-teleoperation task and a simulated indirect-vision driving task in various terrains. Overall, participants completed their tasks significantly faster with the SDs in three-dimensional (3D) mode than with the SDs in the baseline 2D mode. They also navigated more accurately with the SDs in 3D mode. When the effectiveness of the two types of SDs was examined separately, results showed that the active shutter-glasses SD resulted in faster responses and task completion times than the passive polarised SD, though most of the differences failed to reach statistical significance. Perceived workload when interacting with the two SD systems did not differ significantly between the active versus passive display types or between the 3D and 2D modes of operation; however, participants reported more severe discomfort after interacting with the passive polarised SD.     

A comparative analysis of video codecs for multihop wireless video sensor networks

Wireless video sensor networks (WVSNs) have drawn significant attention in recent years due to the advent of low-cost miniaturized cameras, which makes it feasible to realize large-scale WVSNs for a variety of applications including security surveillance, environmental tracking, and health monitoring. However, the conventional video coding paradigms are not suitable for WVSNs due to resource constraints such as limited computation power, battery energy, and network bandwidth. In this paper, we evaluated and analyzed the performance of video codecs based on emerging video coding paradigms such as distributed video coding and distributed compressive video sensing for multihop WVSNs. The main objective of this work was to provide an insight into the computational (encoding/decoding) complexity, energy consumption, node and network lifetime, processing and memory requirements, and the quality of reconstruction of these video codecs. Based on the findings, this paper also provides some guidelines for the selection of appropriate video codecs for a given WVSN application.     

Synthesis and characterization of novel curcumin based polyurethanes varying diisocyanates structure

In this research work, novel polyurethanes (PUs) based on blends of curcumin/1,4-butane diol (BDO) by varying the structure of diisocyanates were prepared following step growth polymerization. Structural study of blends and various diisocyanates based PU through Fourier Transform Infrared (FTIR) spectroscopy confirmed the incorporation of curcumin into the backbone of the PU. The scanning electron microscopic (SEM) study confirmed the well dispersion of incorporated curcumin and homogeneity of surface of synthesized samples. The SEM results also indicated that surface morphology of synthesized samples much dependent on diisocynates structure. Moreover SEM images inferred that phase separation is more pronounced in aromatic diisocyanate based PU. The anti-bacterial and anti-fungal tests were performed against different strains in order to determine the biocompatibility of the curcumin based PU. The antimicrobial activity results revealed that the material having aromatic diisocyanate are more biocompatible than the aliphatic diisocyanates in the PU structure. On the whole, this work is actually a step towards the generation of novel biocompatible materials preferably useful for biomedical applications.     

Influence of metal‐oxide‐supported bentonites on the pyrolysis behavior of polypropylene and high‐density polyethylene

In this article, we report on the pyrolysis of polypropylene (PP) and high‐density polyethylene (HDPE) in the absence and presence of plain and metal‐oxide‐impregnated bentonite clays [BCs; acid‐washed bentonite clay (AWBC), Zn/AWBC, Ni/AWBC, Co/AWBC, Fe/AWBC, and Mn/AWBC] into useful products. Thermal and catalytic runs were performed at 300°C in the case of PP and at 350°C in the case of HDPE for a contact time of 30 min. The effects of different catalysts and their concentrations on the overall yields and the yields of liquid, gas, and residue were studied. The efficacy of each catalyst is reported on the basis of the highest liquid yields (in weight percentage). The derived liquid products were analyzed by Fourier transform infrared spectroscopy and gas chromatography–mass spectroscopy; this confirmed the presence of paraffins, olefins, and naphthenes. The results indicate the catalytic role of impregnated BCs compared to plain BC with the optimum efficiency shown by Co/AWBC in the case of PP and Zn/AWBC in the case of HDPE toward the formation of liquid products in a desirable C range with the enrichment of olefins and naphthenes in the case of PP and paraffins and olefins in the case of HDPE compared to the thermal run. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132, 41221.     

Why Parents Drive Children to School: Implications for Safe Routes to School Programs

Problem: Rates of walking and bicycling to school have declined sharply in recent decades, and federal and state governments have committed funds to reverse these trends. To increase rates of walking and biking to school will require understanding why many parents choose to drive their children to school and how well existing programs, like Safe Routes to School, work.

Purpose: We aimed to understand why many parents choose to drive their children even short distances to school, and what implications this has for programs to increase walking and biking to school.

Methods: We used data from a telephone survey to explore why parents drive their children to school.

Results and conclusions: We found that 75% of parents driving their children less than 2 miles to school said they did this for convenience and to save time. Nearly half of parents driving their children less than 2 miles did not allow their child to walk to school without adult supervision. Accompanying a child on a walk to school greatly increases the time the household devotes to such a trip. Few Safe Routes to School programs effectively address issues of parental convenience and time constraints.

Takeaway for practice: Safe Routes to School programs should take parental convenience and time constraints into account by providing ways children can walk to school supervised by someone other than the parent, such as by using walking school buses. To be effective, such programs need institutional support. Schools should take a multimodal approach to pupil transportation.

Research support: This research was funded by the Active Living Research program of the Robert Wood Johnson Foundation and the U.S. and California Departments of Transportation through the University of California Transportation Center.     

pH Responsive Abelmoschus esculentus Mucilage and Administration of Methotrexate: In-Vitro Antitumor and In-Vivo Toxicity Evaluation

The rapid progression in biomaterial nanotechnology apprehends the potential of non-toxic and potent polysaccharide delivery modules to overcome oral chemotherapeutic challenges. The present study is aimed to design, fabricate and characterize polysaccharide nanoparticles for methotrexate (MTX) delivery. The nanoparticles (NPs) were prepared by Abelmoschus esculentus mucilage (AEM) and chitosan (CS) by the modified coacervation method, followed by ultra-sonification. The NPs showed much better pharmaceutical properties with a spherical shape and smooth surface of 213.4–254.2 nm with PDI ranging between 0.279–0.485 size with entrapment efficiency varying from 42.08 ± 1.2 to 72.23 ± 2.0. The results revealed NPs to possess positive zeta potential and a low polydispersity index (PDI). The in-vitro drug release showed a sustained release of the drug up to 32 h with pH-dependence. Blank AEM -CS NPs showed no in-vivo toxicity for a time duration of 14 days, accompanied by high cytotoxic effects of optimized MTX loaded NPs against MCF-7 and MD-MBA231 cells by MTT assay. In conclusion, the findings advocated the therapeutic potential of AEM/CS NPs as an efficacious tool, offering a new perspective for pH-responsive routing of anticancer drugs with tumor cells as a target.     

Biomass Smoke Exposure Enhances Rhinovirus-Induced Inflammation in Primary Lung Fibroblasts

Biomass smoke is one of the major air pollutants and contributors of household air pollution worldwide. More than 3 billion people use biomass fuels for cooking and heating, while other sources of exposure are from the occurrence of bushfires and occupational conditions. Persistent biomass smoke exposure has been associated with acute lower respiratory infection (ALRI) as a major environmental risk factor. Children under the age of five years are the most susceptible in developing severe ALRI, which accounts for 940,000 deaths globally. Around 90% of cases are attributed to viral infections, such as influenza, adenovirus, and rhinovirus. Although several epidemiological studies have generated substantial evidence of the association of biomass smoke and respiratory infections, the underlying mechanism is still unknown. Using an in vitro model, primary human lung fibroblasts were stimulated with biomass smoke extract (BME), specifically investigating hardwood and softwood types, and human rhinovirus-16 for 24 h. Production of pro-inflammatory mediators, such as IL-6 and IL-8, were measured via ELISA. Firstly, we found that hardwood and softwood smoke extract (1%) up-regulate IL-6 and IL-8 release (p ≤ 0.05). In addition, human rhinovirus-16 further increased biomass smoke-induced IL-8 in fibroblasts, in comparison to the two stimulatory agents alone. We also investigated the effect of biomass smoke on viral susceptibility by measuring viral load, and found no significant changes between BME exposed and non-exposed infected fibroblasts. Activated signaling pathways for IL-6 and IL-8 production by BME stimulation were examined using signaling pathway inhibitors. p38 MAPK inhibitor SB239063 significantly attenuated IL-6 and IL-8 release the most (p ≤ 0.05). This study demonstrated that biomass smoke can modulate rhinovirus-induced inflammation during infection, which can alter the severity of the disease. The mechanism by which biomass smoke exposure increases inflammation in the lungs can be targeted and inhibited via p38 MAP kinase pathway.     

Cognitive styles and life events interact to predict bipolar and unipolar symptomatology.

This study examined the interaction of cognitive style (as assessed self-report and information-processing battery) and stressful life events in predicting the clinician-rated depressive and manic symptomatology of participants with Research Diagnostic Criteria lifetime diagnoses of bipolar disorder (n?=?49), unipolar depression (n?=?97), or no lifetime diagnosis (n?=?23). Bipolar and unipolar participants' attributional styles, dysfunctional attitudes, and negative self-referent information processing as assessed at Time 1 interacted significantly with the number of negative life events that occurred between Times 1 and 2 to predict increases in depressive symptoms from Time 1 to Time 2. Within the bipolar group, participants' Time 1 attributional styles and dysfunctional attitudes interacted significantly, and their self-referent information processing interacted marginally, with intervening life events to predict increases in manic symptoms from Time 1 to Time 2. These findings provide support for the applicability of cognitive vulnerability–stress theories of depression to bipolar spectrum disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)