Reconfigurable fault tolerant networks for fast packet switching

The authors consider the design and analysis of reconfigurable networks for fast packet switching. The design constraints resulting from the use of fast packet switching that affect fault-tolerant network design are carefully studied. A reconfigurable network with high link redundancy is then proposed. An abstract replacement model that characterizes the proposed reconfigurable network is presented. Network fault tolerance problems are transformed into well known assignment problems. Two practical designs based on feasible technology are presented. An appreciable reliability improvements is achieved and full bandwidth is maintained up to a tolerable level of failures, with relatively few spare switches     

Investigation of the stability of tablets prepared from sucrose and citric acid anhydride utilizing response surface methodology

Inversion of sucrose is a stability problem particularly of candies with acidic taste that contain sucrose and small amounts of organic acids such as citric acid, since the free d-fructose produced by hydrolysis is hygroscopic. The following possibilities were investigated for preventing the hydrolysis of sucrose in tablets containing sucrose and citric acid: Adding various amounts of tri-sodium citrate to the formulation to neutralize the citric acid, (Hot) melt coating of citric acid and tri-sodium citrate with a vegetable fat at different coating ratios, variation of the ratio of coated citric acid and tri-sodium citrate in formulations, and compressing the formulations with different compression forces. After tablet processing and storage of tablets, the concentration of d-fructose was determined on the basis of enzymatic reactions. A response surface central composite design was used. The above-mentioned variations were chosen as independent variables and the amount of d-fructose was chosen as response variable. The lowest rates of inversion could be achieved by increasing the content of tri-sodium citrate and the ratio of coating material and decreasing the ratio of coated citric acid and tri-sodium citrate in the tablet formulations. The compression force had no significant effect on the inversion of sucrose.     

Towards efficient partial evaluation in logic programming

Partial evaluation is a symbolic manipulation technique used to produce efficient algorithms when part of the input to the algorithm is known. Other applications of partial evaluators such as universal compilation and compiler generation are also known to be possible. A partial evaluator receives as input a program and partially known input to that program, and outputs a residual program which should run at least as efficient as the input program with restricted input. In this paper we study the case where both the input and residual programs are logic programs, being the partial evaluator itself a logic program. Up to now, partial evaluators have failed to process large “non=toy” examples. Here we present extensions to partial evaluators whic will allow us to produce more efficient residual programs using less computing resources, during partial evaluation. First, the introduced extensions allow the processing of large examples, which is not possible with the previous techniques. This is now possible since the extensions use less CPU time and memory consumption during the partial evaluation process. Second, the extended partial evaluator produces smaller residual programs, producing important CPU time optimizing effects. With the standard techniques, a partial evaluator will most probably act as a pessimizer, not as an optimizer. Examples are given.     

A constant-volume gas pump for gas electrodes

A pump suitable for use with gas electrodes, in which recirculation of the gas is necessary, is described. The system to which the cell with the gas electrode and the pump are connected does not change its volume when the pump is in operation. The pump works as follows: an embolus, consisting of a Tefloncoated magnetic stirring bar, placed inside a glass tube having an internal diameter slightly larger than the diameter of the bar, is moved from the outside with a permanent magnet, which in turn is moved horizontally along the tube by means of a mechanical assembly driven by an electric motor. The motion of the embolus is accompanied by the closing and opening of glass valves which allow the gas to circulate in the desired direction. The pump, used in conjunction with a vacuum line, operates from pressures as low as 60 Torr to above atmospheric pressure. The operation of the pump is unaffected by organic gases and most inorganic gases.     

Visual tracking for the recovery of multiple interacting plant root systems from X-ray $$\upmu $$CT images

We propose a visual object tracking framework for the extraction of multiple interacting plant root systems from three-dimensional X-ray micro computed tomography images of plants grown in soil. Our method is based on a level set framework guided by a greyscale intensity distribution model to identify object boundaries in image cross-sections. Root objects are followed through the data volume, while updating the tracker’s appearance models to adapt to changing intensity values. In the presence of multiple root systems, multiple trackers can be used, but need to distinguish target objects from one another in order to correctly associate roots with their originating plants. Since root objects are expected to exhibit similar greyscale intensity distributions, shape information is used to constrain the evolving level set interfaces in order to lock trackers to their correct targets. The proposed method is tested on root systems of wheat plants grown in soil.     

Influence of Unmodified and β-Glycerophosphate Cross-Linked Chitosan on Anti-Candida Activity of Clotrimazole in Semi-Solid Delivery Systems

The combination of an antifungal agent and drug carrier with adjunctive antimicrobial properties represents novel strategy of complex therapy in pharmaceutical technology. The goal of this study was to investigate the unmodified and ion cross-linked chitosan’s influence on anti-Candida activity of clotrimazole used as a model drug in hydrogels. It was particularly crucial to explore whether the chitosans’ structure modification by β-glycerophosphate altered its antifungal properties. Antifungal studies (performed by plate diffusion method according to CLSI reference protocol) revealed that hydrogels obtained with chitosan/β-glycerophosphate displayed lower anti-Candida effect, probably as a result of weakened polycationic properties of chitosan in the presence of ion cross-linker. Designed chitosan hydrogels with clotrimazole were found to be more efficient against tested Candida strains and showed more favorable drug release profile compared to commercially available product. These observations indicate that novel chitosan formulations may be considered as promising semi-solid delivery system of clotrimazole.     

The dorsolateral pre‑frontal cortex bi‑polar error‑related potential in a locked‑in patient implanted with a daily use brain–computer interface

While brain computer interfaces (BCIs) offer the potential of allowing those suffering from loss of muscle control to once again fully engage with their environment by bypassing the affected motor system and decoding user intentions directly from brain activity, they are prone to errors. One possible avenue for BCI performance improvement is to detect when the BCI user perceives the BCI to have made an unintended action and thus take corrective actions. Error-related potentials (ErrPs) are neural correlates of error awareness and as such can provide an indication of when a BCI system is not performing according to the user’s intentions. Here, we investigate the brain signals of an implanted BCI user suffering from locked-in syndrome (LIS) due to late-stage ALS that prevents her from being able to speak or move but not from using her BCI at home on a daily basis to communicate, for the presence of error-related signals. We first establish the presence of an ErrP originating from the dorsolateral pre-frontal cortex (dLPFC) in response to errors made during a discrete feedback task that mimics the click-based spelling software she uses to communicate. Then, we show that this ErrP can also be elicited by cursor movement errors in a continuous BCI cursor control task. This work represents a first step toward detecting ErrPs during the daily home use of a communications BCI.     

Carbon‐Nanotube–PDMS Composite Coatings on Optical Fibers for All‐Optical Ultrasound Imaging

Polymer–carbon nanotube composite coatings have properties that are desirable for a wide range of applications. However, fabrication of these coatings onto submillimeter structures with the efficient use of nanotubes has been challenging. Polydimethylsiloxane (PDMS)–carbon nanotube composite coatings are of particular interest for optical ultrasound transmission, which shows promise for biomedical imaging and therapeutic applications. In this study, methods for fabricating composite coatings comprising PDMS and multiwalled carbon nanotubes (MWCNTs) with submicrometer thickness are developed and used to coat the distal ends of optical fibers. These methods include creating a MWCNT organogel using two solvents, dip coating of this organogel, and subsequent overcoating with PDMS. These coated fibers are used as all‐optical ultrasound transmitters that achieve high ultrasound pressures (up to 21.5 MPa peak‐to‐peak) and broad frequency bandwidths (up to 39.8 MHz). Their clinical potential is demonstrated with all‐optical pulse‐echo ultrasound imaging of an aorta. The fabrication methods in this paper allow for the creation of thin, uniform carbon nanotube composites on miniature or temperature‐sensitive surfaces, to enable a wide range of advanced sensing capabilities.     

Optimum transmission ranges in a direct-sequence spread-spectrummultihop packet radio network

The authors obtain the optimum transmission ranges to maximize throughput for a direct-sequence spread-spectrum multihop packet radio network. In the analysis, they model the network self-interference as a random variable which is equal to the sum of the interference power of all other terminals plus background noise. The model is applicable to other spread-spectrum schemes where the interference of one user appears as a noise source with constant power spectral density to the other users. The network terminals are modeled as a random Poisson field of interference power emitters. The statistics of the interference power at a receiving terminal are obtained and shown to be the stable distributions of a parameter that is dependent on the propagation power loss law. The optimum transmission range in such a network is of the form CK^α where C is a constant, K is a function of the processing gain, the background noise power spectral density, and the degree of error-correction coding used, and α is related to the power loss law. The results obtained can be used in heuristics to determine optimum routing strategies in multihop networks     

Double Loop Network Architectures--A Performance Study

Single loop networks tend to become unreliable and suffer from poor performance when the number of nodes in the network becomes large. One approach to increasing reliability and improving performance is to use a double loop. In this paper, the performance (using analytical and simulation models) of a class of highly reliable double loop network architectures is presented. The richer topology of double loop networks allows more sophisticated routing algorithms to be used. Several routing algorithms are studied, including: fixed, adaptive to failure, and fully adaptive to failure and traffic load conditions.