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排序方式: 共有89条查询结果,搜索用时 0 毫秒
1.
Teoman Dogru Ali Kirik Hasan Gurel Ali A. Rizvi Manfredi Rizzo Alper Sonmez 《International journal of molecular sciences》2021,22(12)
Nonalcoholic fatty liver disease (NAFLD) is strongly associated to the features of metabolic syndrome which can progress to cirrhosis, liver failure and hepatocellular carcinoma. However, the most common cause of mortality in people with NAFLD is not liver-related but stems from atherosclerotic cardiovascular disease (CVD). The prevalence of NAFLD is on the rise, mainly as a consequence of its close association with two major worldwide epidemics, obesity and type 2 diabetes (T2D). The exact pathogenesis of NAFLD and especially the mechanisms leading to disease progression and CVD have not been completely elucidated. Human fetuin-A (alpha-2-Heremans Schmid glycoprotein), a glycoprotein produced by the liver and abundantly secreted into the circulation appears to play a role in insulin resistance, metabolic syndrome and inflammation. This review discusses the links between NAFLD and CVD by specifically focusing on fetuin-A’s function in the pathogenesis of NAFLD and atherosclerotic CVD. 相似文献
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Teoman Tinçer 《应用聚合物科学杂志》2016,133(17)
Polyethylene (PE) is one of the most widely produced and widely used plastics in the world. Saturated hydrocarbons cannot absorb the energy of the light reaching earth, so the degradation process is rather slow; this, in return, causes disposal problems. On the other hand, it was observed that in the presence of oxygen and impurities in the polymer matrix, the degradation could be reduced to shorter time intervals. In this study, vanadium(III) acetyl acetonate (VAc), serpentine (SE), and Cloisite 30B (CL) were used as additives, both together and alone, and we followed the photodegradation of PE. The amount of VAc was kept constant at 0.2 wt %, whereas the amounts of SE and CL were varied between 1 and 4 wt %. The samples were irradiated by UV light for up to 500 h. Mechanical and spectroscopic measurements were carried out during certain time intervals to monitor the degradation. VAc containing PE showed the fastest degradation. The elongation at break values of these samples were reduced to half of the initial value of elongation at break within five days. Combinations of the CL and SE additives were also proven to accelerate the degradation of PE; this was followed by an increase in the carbonyl index, which was observed to be at least 10 times greater than that of pure PE. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 43354. 相似文献
5.
Olga Procházková Jan Grym Ladislav Pekárek Jiří Zavadil Karel Žďánský 《Journal of Materials Science: Materials in Electronics》2008,19(8-9):770-775
We report the preparation of semi-insulating InP single crystals of p-type conductivity and intentionally undoped p-type epitaxial layers for radiation detection. We focus on (i) the growth of InP single crystals doped with copper by the Czochralski technique and their subsequent temperature annealing to convert them to a semi-insulating (SI) state of p-type conductivity, and (ii) the growth of thick (>10 μm) p-type InP layers by liquid phase epitaxy with an admixture of Pr and Dy. Grown layers and single crystals were examined by low-temperature photoluminescence spectroscopy, capacitance-voltage and temperature dependent Hall measurements. An efficient purification due to rare earth (RE) admixture has been observed and layers grown with the addition of Pr and Dy exhibit the change of electrical conductivity from n to p at certain RE concentration in the melt. Dominant acceptors responsible for conductivity conversion have been identified. Three types of detection structures exploiting the Schottky or Schottky like contacts on pure and SI p-type InP or exploiting the p–n junction were designed. 相似文献
6.
A significant proportion of extruded aluminum sections have capacities beyond yield strength. In this study, the ultimate inelastic capacity is investigated for laterally supported aluminum flexural members symmetrical about bending axis. The topics studied include ultimate compressive stresses for component plate elements of flexural members, ultimate shape factors, and improvements to the existing weighted average strength approach. A parametric study using finite element analysis as well as physical tests was conducted to validate the approaches developed in this study. The study shows that the proposed approaches predict the ultimate inelastic flexural strength of aluminum members accurately. 相似文献
7.
Ceylan Zafer Mahmut Kus Gulsah Turkmen Haluk Dincalp Serafettin Demic Baha Kuban Yildirim Teoman Siddik Icli 《Solar Energy Materials & Solar Cells》2007,91(5):427-431
We have studied the influence of the spacer alkyl chain length of perylenemonoimide (PMI) dyes on the device performance in dye-sensitized solar cells (DSSCs). We observed that the dyes with longer and brunched alkyl chains exhibit higher efficiencies in DSSCs. In line with these statements we now report the highest efficiency obtained under standard conditions for a perylene imide derivative with PMI-DA1 that performs 300 mV open circuit voltage, 9.79 mA/cm2 short-circuit current and 1.61% overall conversion efficiency. 相似文献
8.
Teoman Özer 《International Journal of Engineering Science》2003,41(18):2193-2211
In this study the symmetry groups of two-dimensional elastodynamics problems in nonlocal elasticity are identified and classified. The determining equations are found, and then the differential equations are obtained that include the kernel function and the independent term. The symmetry group classification is determined by using these differential equations and solutions of the determining equations. 相似文献
9.
Tamariz E Wan AC Pek YS Giordano M Hernández-Padrón G Varela-Echavarría A Velasco I Castaño VM 《Journal of materials science. Materials in medicine》2011,22(9):2097-2109
Chemotropic proteins guide neuronal projections to their final target during embryo development and are useful to guide axons
of neurons used in transplantation therapies. Site-specific delivery of the proteins however is needed for their application
in the brain to avoid degradation and pleiotropic affects. In the present study we report the use of Poly (ethylene glycol)-Silica
(PEG-Si) nanocomposite gel with thixotropic properties that make it injectable and suitable for delivery of the chemotropic
protein semaphorin 3A. PEG-Si gel forms a functional gradient of semaphorin that enhances axon outgrowth of dopaminergic neurons
from rat embryos or differentiated from stem cells in culture. It is not cytotoxic and its properties allowed its injection
into the striatum without inflammatory response in the short term. Long term implantation however led to an increase in macrophages
and glial cells. The inflammatory response could have resulted from non-degraded silica particles, as observed in biodegradation
assays. 相似文献
10.
In the present work, change of rod-like micelle sizes with change of amphiphile concentration in hexagonal mesophase and the effect of inorganic salt additions on the effective length of these micelles have been studied. The investigations were made by the using of electrical conductivity method in shear flow. The dependence of form factor on the anisometricity parameter of rod-like micelles were determined for investigated lyotropic systems. 相似文献